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Effervescent preparation containing complete plant tissue and preparation technology of effervescent preparation

A plant tissue and effervescent preparation technology, which is applied in the direction of medical preparations of non-active ingredients, drug delivery, pill delivery, etc., can solve the problems of high cost, complicated production process, and great difficulty, so as to relieve pressure and make the production process simple , beautiful appearance effect

Active Publication Date: 2019-09-17
KUNMING MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But at the same time, it also has the following disadvantages: ①The production process is complicated and difficult; ②The cost is high; ③The packaging requirements are strict and moisture-proof; ④It can only be taken after dissolving, and cannot be swallowed directly.
However, more intact plant tissues are difficult to prepare pellets for tableting due to their larger size
In addition, if a large piece of plant tissue is forcibly mixed into the prepared granules for tableting, it will also hinder the normal tableting due to its poor fluidity. Unable to unload and press tablet

Method used

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  • Effervescent preparation containing complete plant tissue and preparation technology of effervescent preparation
  • Effervescent preparation containing complete plant tissue and preparation technology of effervescent preparation
  • Effervescent preparation containing complete plant tissue and preparation technology of effervescent preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] The preparation of embodiment 1 plant tissue mass

[0030] Table 1 Recipe for rose petal clumps

[0031]

[0032] In this embodiment, dry rose petals are used to prepare plant tissue lumps, which are rose petal lumps in this embodiment, and the longest diameter of the rose petals used after flattening is not greater than 2.5 cm. If the petals are too large, they can be chopped or coarsely powdered before use. Prepare according to the prescription ratio in Table 1 and follow the following steps: (1) dissolve and disperse the corresponding adhesive with purified water to prepare a glue; (2) mix the dried rose petals with the glue, and fully wet it; ( 3) kneading the rose petals wetted by the glue into a compact mass; (4) drying at room temperature or in an oven to obtain plant tissue mass. All of the above-mentioned prescriptions 1 to 9 can prepare near-spherical agglomerates with a diameter of 2-5 mm.

[0033] In this embodiment, we use gelatin, gum arabic, polyvinyl...

Embodiment 2

[0034] Embodiment 2 Various plant tissue mass preparations

[0035] Table 2 Plant tissue mass prescription

[0036]

[0037] According to the prescription ratio in Table 2 and the steps described in Example 1, various plant tissue agglomerates were prepared, and more than 70% (w / w) of the obtained various plant tissue agglomerates had a diameter less than 5 mm.

Embodiment 3

[0038] The preparation of embodiment 3 rose lump effervescent tablet (classic prescription)+expand to other petal lumps

[0039] Prescription 18:

[0040]

[0041] Prescription 19:

[0042]

[0043] Prescription 20:

[0044]

[0045] Prescription 21:

[0046]

[0047] Prescription 22:

[0048]

[0049]

[0050] Prescription 23:

[0051]

[0052] Prescription 24:

[0053]

[0054] In this example, the preparation process of prescriptions 18 to 24 is as follows, and the recipes and preparation methods of various plant tissue lumps used are shown in Example 1 and Example 2.

[0055] Preparation process: (1) Divide the starch and sucrose in the prescription into two parts evenly, one part is mixed with citric acid (i.e. sucrose, starch, citric acid), and the other part is mixed with sodium bicarbonate (i.e. bicarbonate sodium, starch, citric acid), and then use an appropriate amount of purified water as a wetting agent to prepare soft materials; (3) t...

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Abstract

The invention provides an effervescent preparation containing complete plant tissue and a preparation technology of the effervescent preparation. The effervescent preparation is prepared from the complete plant tissue, an adhesive, organic acid, alkali, a filler and the like. The effervescent preparation contains complete tissue of plant flowers, plant fruits, plant leaves and the like, the preparation technology is simple and convenient, beautiful and natural feeling can be brought to a user, and fragrance of natural plants can be better preserved.

Description

technical field [0001] The invention relates to the field of pharmaceutical preparations, in particular to an effervescent preparation containing intact plant tissues and a preparation process thereof. Background technique [0002] With the change of human living environment and the increase of life pressure, the incidence of many lifestyle-related chronic diseases has increased and the age of onset has advanced. Therefore, more and more groups realize the importance of health care and gradually integrate health care into their daily life. Among them, plant foods derived from natural flowers, fruits, leaves and other materials have long-term experience in human use and relatively systematic and in-depth basic research, so they are superior in terms of curative effect, safety and audience acceptance. Has a development advantage. It is precisely because of this that a large number of food and health products based on natural plants are more common in the consumer market and ...

Claims

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Application Information

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IPC IPC(8): A61K9/46A61K47/46
CPCA61K9/0007A61K9/2068
Inventor 佘振南翁稚颖谢磊马怡涵赵韫琦
Owner KUNMING MEDICAL UNIVERSITY
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