Mesenchymal stem cell preparation and preparing method and application thereof
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- 山东佰鸿干细胞生物技术有限公司
- Publication Date
- 2019-10-25
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
technical field
[0001] The invention belongs to the field of biomedicine, and in particular relates to a mesenchymal stem cell preparation for treating rheumatoid arthritis and a preparation method thereof. Background technique
[0002] Rheumatoid arthritis (RA) is a chronic, inflammatory synovitis-based systemic disease of unknown etiology. It is characterized by polyarticular, symmetrical, and aggressive arthritis of the small joints of the hands and feet, often accompanied by involvement of extra-articular organs and positive serum rheumatoid factor, which can lead to joint deformities and loss of function. RA is more common in women, and the incidence rate is 2 to 3 times that of men. It can occur at any age, and the high incidence age is 40 to 60 years old. The pathogenesis of RA may be related to heredity, infection, and sex hormones. The pathology of RA arthritis mainly includes the proliferation of synovial lining cells, the infiltration of a large number of infla...