Traditional Chinese medicine feed additive for preventing and treating recessive mastitis of dairy stocks and preparation method of traditional Chinese medicine feed additive

A technology for recessive mastitis and feed additives, applied in animal feed, animal feed, pharmaceutical formulations, etc., can solve problems such as multi-drug resistance, and achieve the effects of preventing mastitis, promoting production, and improving milk production.

Inactive Publication Date: 2019-10-29
NORTHWEST A & F UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is often a mixed infection of multiple strains, and the isolated pathogenic bacteria have different degrees of drug resistance to commonly used clinical antibacterial drugs, and present multi-drug resistance

Method used

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  • Traditional Chinese medicine feed additive for preventing and treating recessive mastitis of dairy stocks and preparation method of traditional Chinese medicine feed additive
  • Traditional Chinese medicine feed additive for preventing and treating recessive mastitis of dairy stocks and preparation method of traditional Chinese medicine feed additive

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Example 1 Main pharmacodynamic test

[0018] 1.1 The prevention and treatment effect of traditional Chinese medicine additives on dairy cows recessive mastitis

[0019] According to the DHI test results, combined with the clinical examination of the on-site veterinarian, the chronic dairy cow mastitis was screened out (onset for a longer period of time, the milk production of dairy cows is reduced, the milk is mixed with flocs, the milk is thin or gray, and the breasts are palpated. ). A total of 240 cows in a dairy farm were divided into 2 groups, 191 cows in the normal feeding group and 49 cows in the recessive mastitis group (the cows have no obvious clinical mastitis symptoms, normal lactation, and no visible abnormalities in the milk, but the DHI is being measured If the number of somatic cells is greater than 300,000 / mL), add 100 g of Chinese herbal medicine compound additives to the diets of each group of cows for a total of 30 days. Detect milk fat percentage, prot...

Embodiment 2

[0023] Example 2 Effect of Chinese herbal medicine additives on related enzymes in whey of dairy cows with recessive mastitis

[0024] NAG is a lysozyme. During the period of latent mastitis in cattle, the increase of white blood cells in the milk will also lead to the increase of NAG activity; lactate dehydrogenase (LDH) can be used as a specific indicator for early diagnosis of mastitis. In this experiment, 30 cows of a certain breed of Holstein were selected, including: 10 healthy cows as healthy group and 20 cows with recessive mastitis (the result of CMT test and diagnosis shaking plate is +++~++++), Recessive mastitis was divided into prevention and treatment group and control group, each with 10 heads. Among them, the control group was taken with Chinese herbal medicine feed additives, 100 g / day per cow, and Chinese herbal medicine feed additives were used for 7 days. The healthy group and the control group did not use any drugs. Aseptically collect milk samples as requir...

Embodiment 3

[0028] Example 3 The preventive effect of Chinese herbal additives on latent mastitis in dairy goats

[0029] In a Shanen dairy goat farm in Shaanxi Province, the whole group selected 50 healthy dairy goats, which were added for 7 days a month for 3 months. Compared with the control group, the average milk production of the dairy goats increased, and the somatic cells in the milk Significantly reduced, the milk fat rate, protein rate, fat-to-egg ratio and urea nitrogen did not change much, meeting the requirements.

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Abstract

The invention discloses a feed additive for preventing and treating recessive mastitis of dairy stocks. The feed additive consists of the following raw material medicines by weight of 6-8g of a wholesnakegourd fruit extract, 3-4g of a rhizoma ligustici wallichii extract, 4-5g of a radix angelicae extract, 6-8g of a radix angelicae sinensis extract, 6-8g of a honeysuckle flower extract, 6-8g of afructus forsythiae extract, 4-5g of an immature tangerine peel extract, 6-8g of a Chinese thorowax extract, 8-12g of a dandelion extract, 8-12g of a herba violae extract, 6-8g of a radix paeoniae rubra extract, 8-12g of a raw milkvetch root extract, 8-12g of a radix codonopsis extract, 4-5g of a dried orange peel extract, 3-4g of a licorice root extract, 100-200g of red jujube powder and 100-300gof selenium yeast. The feed additive has the efficacy of clearing heat, removing toxicity, dispersing stagnated liver qi for relieving qi stagnation, restoring menstrual flow, promoting blood circulation, activating collaterals, promoting lactation and the like, can prevent and treat recessive mastitis of the dairy stocks, can reduce the number of somatic cells in breasts, and can increase the milk production.

Description

Technical field [0001] The invention relates to a Chinese herbal medicine feed additive for dairy animals, in particular to a Chinese herbal medicine feed additive for preventing and treating latent mastitis of dairy animals and a preparation method thereof. Background technique [0002] Mastitis is one of the main diseases that endanger the dairy industry, mainly divided into clinical mastitis and recessive mastitis. From 2015 to 2018, the incidence of dairy cow mastitis and the isolation and detection of pathogenic bacteria were conducted on cattle farms in some areas of Shaanxi. The incidence of clinical mastitis was 4.5% to 11.5%, and the incidence of recessive mastitis was 15% to 45. %. Among the pathogenic bacteria isolated from clinical mastitis, 22.2% of Staphylococcus aureus, 22.2% of Escherichia coli, 27.8% of Streptococcus, 14.8% of Pseudomonas aeruginosa, and 9.26% of Shigella were isolated from 193 cows with recessive mastitis. Among the pathogenic bacteria, Staphy...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/86A61P15/14A61P31/04A23K50/10A23K10/30A23K20/20A61K33/04
CPCA61K33/04A61K36/064A61K36/232A61K36/233A61K36/236A61K36/288A61K36/344A61K36/355A61K36/428A61K36/481A61K36/484A61K36/634A61K36/65A61K36/71A61K36/725A61K36/752A61K36/86A23K10/30A23K20/20A23K50/10A61P15/14A61P31/04A61K2300/00Y02P60/87
Inventor 张为民卿素珠张锦轩范云鹏麻武仁郭抗抗
Owner NORTHWEST A & F UNIV
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