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Cannabidiol-containing composition for treating muscle spasm and preparation method thereof

A technology of cannabidiol and muscle spasm, which is applied in the field of cannabidiol-containing compositions and its preparation, can solve problems such as ineffective treatment of muscle spasm, achieve the effects of promoting local blood circulation, relieving stimulation and compression, and promoting the cessation of spasm Effect

Inactive Publication Date: 2019-11-05
李卫
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to solve the problem that the above-mentioned prior art cannot effectively treat muscle spasms, the present invention provides a composition containing cannabidiol for treating muscle spasms and a preparation method thereof

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] This example provides a composition containing cannabidiol for the treatment of muscle spasm, which mainly includes the following components by mass: 10-50 parts of cannabidiol, 10-30 parts of acteoside, total flavonoids of safflower 10-30 parts, 10-20 parts of curcumin, 10-15 parts of sodium polyacrylate, 8-12 parts of polyvinylpyrrolidone, 1-5 parts of alum, 1-3 parts of EDTA, 20-30 parts of propylene glycol, 10 parts of tourmaline powder ~15 parts and 2~4 parts of sodium carboxymethylcellulose.

[0038] In this example, cannabidiol has antioxidant effect and is a natural neuroprotective agent, which can reduce oxidative stress, prevent necrosis of muscle neurons, repair muscle and nerve damage, and reduce the risk of ischemic injury; acteoside is The effective medicinal ingredients of Fangfeng have analgesic and antispasmodic effects; total flavonoids of safflower can expand blood vessels, improve the effect of blood microcirculation in the affected area, quickly res...

Embodiment 2

[0040] This embodiment provides a composition containing cannabidiol for the treatment of muscle spasm, which mainly includes the following components by mass: 30 parts of cannabidiol and 20 parts of acteoside , 20 parts of safflower total flavonoids, 15 parts of curcumin, 12 parts of sodium polyacrylate, 10 parts of polyvinylpyrrolidone, 3 parts of alum, 2 parts of EDTA, 25 parts of propylene glycol, 12 parts of tourmaline powder and 3 parts of sodium carboxymethyl cellulose .

Embodiment 3

[0042] This embodiment provides a composition containing cannabidiol for the treatment of muscle spasm, mainly including the following components by mass: 20 parts of cannabidiol, 15 parts of acteoside , 15 parts of safflower total flavonoids, 12 parts of curcumin, 13 parts of sodium polyacrylate, 8 parts of polyvinylpyrrolidone, 2 parts of alum, 1 part of EDTA, 24 parts of propylene glycol, 13 parts of tourmaline powder and 2 parts of sodium carboxymethylcellulose share.

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PUM

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Abstract

The invention relates to a cannabidiol-containing composition for treating muscle spasm and a preparation method thereof, and belongs to the technical field of pharmaceutical compositions. In order tosolve the problem that an existing technology cannot effectively treat muscle spasms, the invention provides a cannabidiol-containing composition for treating muscle spasms. Medicinal ingredients include cannabidiol, cimicifugoside, total flavonoids of safflower and curcumin. The medicinal ingredients are evenly dispersed in a gel prepared from sodium polyacrylate, polyvinylpyrrolidone, alum, EDTA and propylene glycol, and then the drug-loaded gel is applied on a substrate with tourmaline powder to obtain a gel dressing composition. The gel dressing composition is applied on the muscle spasmarea. During hot compress, the medicinal ingredients can be rapidly transdermally absorbed to infiltrate to the abnormal motor neurons in the affected area, thus promoting local blood circulation, relieving stimulate and compression applied on the motor nerve, stopping muscle spasm as soon as possible and relieving pain for patients.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical compositions, and in particular relates to a composition containing cannabidiol for treating muscle spasm and a preparation method thereof. Background technique [0002] Muscle cramps are sudden, involuntary tonic contractions of muscles, triggered by excessive exercise, or occurring spontaneously. The cause of muscle spasm is not yet clear. It may be due to a decrease in the threshold of nerve or neuromuscular stress, or the transient electrical triggering of α-motor neurons that trigger skeletal muscle contraction, causing a sudden increase in the nerve action frequency of the muscle, resulting in muscle tonic contraction. [0003] Muscle spasms are most common in the calf and foot muscles, manifested as calf muscles such as the gastrocnemius suddenly become very hard, lasting for a few seconds to tens of seconds, and the pain is unbearable. Muscle spasms often occur when sleeping at nig...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/286A61K9/70A61K47/02A61P21/02A61K31/12A61K31/05A61K31/7032
CPCA61K9/0004A61K9/7053A61K9/7061A61K31/05A61K31/12A61K31/7032A61K36/286A61K47/02A61K2236/19A61K2236/333A61K2236/51A61P21/02A61K2300/00
Inventor 李卫孟庆刚赵立涛孙宇峰卫霖陆峰李赫然孟鑫岳琦吕明明
Owner 李卫