Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

New application of caveolin-1

A technology of caveolin and new use, applied in the field of new use of caveolin-1, which can solve the problem of not finding caveolin and other problems

Inactive Publication Date: 2019-12-10
HUZHOU CENT HOSPITAL
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no relevant report on the relationship between caveolin-1 and ALI.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • New application of caveolin-1
  • New application of caveolin-1

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0009] Materials and Methods

[0010] Main instruments and reagents

[0011] PCR instrument (Biometra, Germany), microtome (Leica, Germany), biological microscope (Nikon 80i, Japan), JD80l gel imaging and analysis system and morphological image analysis system (Jetta, Jiangsu), arteriovenous needle BD0.7 mm (Suzhou BD Medical Instrument Company). LPS (0lll:B4, Sigma, USA), DEX (Jiangsu Hengrui Pharmaceutical Company, batch number: 16060132), TrizoI reagent (Invitrigen, USA), ELISA kit (Hangzhou Lianke Biotechnology Company, batch number: 70-EK3822 / 2) , RIPA lysate (Beyond Institute of Biotechnology, Shanghai), AMV reverse transcription kit, Taq enzyme, dNTP (Promega, USA), Cav-1 PCR primer, TLR-4 PCR primer, P38MAPK primer, internal reference GAPDH primer ( Shanghai Sangong Technology Co., Ltd., Shanghai), rabbit anti-mouse Cav-1 polyclonal antibody Abcam, UK), immunohistochemistry kit (Zhongshan Jinqiao, Beijing), and other reagents are domestic analytical reagents.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the technical field of biomacromolecules, and relates to a new application of caveolin-1. The caveolin-1 is used for prognosis evaluation of lung protection of ALI, and is more particularly used for preparing an ALI prognosis evaluation reagent or kit. A foundation is provided for diagnosis and treatment of acute lung injury.

Description

technical field [0001] The invention belongs to the technical field of biological macromolecules and relates to a new application of caveolin-1. Background technique [0002] Acute lung injury (Acute lung injury, ALI) is caused by a variety of reasons, based on diffuse lung cell damage, characteristic pathological changes in lung tissue structure, pulmonary edema and pulmonary atelectasis as pathological features, rapidly affecting gas Exchange function is the clinical hallmark of pulmonary inflammation and increased permeability syndrome. Its pathological features are alveolar capillary endothelial cells and alveolar epithelial cell damage, manifested as extensive pulmonary edema and tiny atelectasis. The pathophysiological changes are mainly increased intrapulmonary shunt and decreased lung compliance. Clinically, hypoxemia, rapid respiratory rate, and diffuse infiltration of both lungs appeared on chest X-ray. [0003] Caveolin-1 (cav-1) includes two isoforms, cav-1a a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C12Q1/6883G01N33/68
CPCC12Q1/6883C12Q2600/118G01N33/6893G01N2800/12
Inventor 孟志鹏刘静陆蕴红童飞胡四平宋鹏涛曹小飞黄新华
Owner HUZHOU CENT HOSPITAL
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com