9 results about "Lung protection" patented technology

The invention relates to the technical field of medical prediction, in particular to a digital twinborn prediction method for patient lung protective ventilation supported by ECMO, which comprises the following steps: extracting flow velocity change and jump points under the support of ECMO, constructing a ventilation fluctuation trend map, identifying fluctuation sections by combining compliance and pressure value ratio, delimiting lung partitions and analyzing oxygenation ratio trend. And generating an oxygenation capability classification graph, sequencing ventilation path effects, and outputting a pulmonary protective ventilation digital twinborn prediction scheme. According to the method, dynamic response mapping of ventilation behaviors is established on the basis of timing sequence changes of breathing flow velocity jump characteristics and compliance pressure value ratios, the lung regional ventilation state is accurately recognized, lung function zoning division is achieved by combining oxygenation ratio waveform classification, ventilation path utility sorting is completed through oxygenation descending characteristics under path coverage, and the lung function evaluation accuracy is improved. And a path state prediction sequence is constructed by fusing the change relationship between the tensile stress and the ventilation pressure, so that the dynamic adaptability of the ventilation strategy to the lung mechanics and oxygenation state and the region matching precision are improved.

The invention discloses chest surgery lung protection equipment which comprises a neck sleeve, two connecting ropes are connected to the outer side of the neck sleeve, a hard rod is installed at one end of each connecting rope, a protection plate is slidably installed on the outer sides of the two connecting ropes, two grooves are formed in one side of the protection plate, and pressing assemblies used for pressing the connecting ropes are arranged in inner cavities of the grooves. Elastic blocks are installed on the two sides of the protection plate, an attaching belt is connected between the two elastic blocks, a plurality of connecting strips are connected to the middle of one side of the attaching belt, a pull rope is connected to one ends of the connecting strips, a mounting groove is formed in the middle of the protection plate, and an adjusting assembly used for driving the pull rope to move is arranged in an inner cavity of the mounting groove. The binding belt can be detached by detaching the threaded assembly, so that the number of the protective plates on the outer side of the connecting rope is conveniently changed, the positions of the protective plates can be conveniently changed through the pressing assembly, and the protective plates are adjusted according to the size and position of a wound of a patient.

The invention discloses a lung protection function exosome based on resveratrol-astragalus membranaceus-ginseng induction, an inhalation preparation and application, and belongs to the technical field of biology. The exosome is obtained by inducing lung fibroblasts by active ingredients containing resveratrol, an astragalus extract and a ginseng extract and then secreting the lung fibroblasts; wherein the content of astragaloside in the astragalus extract is not less than 2.0%, and the total content of ginsenoside Rg1 and Rb1 in the ginseng extract is not less than 5.0%. The invention also provides a dry powder inhalant or an aerosol inhalation solution containing the exosome. The exosome and the preparation thereof play a lung protection role through multiple mechanisms such as inflammation regulation and control, oxidative stress resistance and repair promotion, can be used for preventing and / or treating various lung injury diseases such as acute lung injury and pneumonia, and have the advantages of good biocompatibility and strong targeting property.

The utility model discloses a thoracic surgery clinical lung protection equipment belongs to thoracic surgery technical field, a thoracic surgery clinical lung protection equipment, including fixed part one and setting in hand fixed part one fixed part two, the both sides between fixed part one and fixed part two are fixedly connected with the buckle belt, fixed arm no.

The present application relates to the application of Huangjing polysaccharide in the preparation of products for preventing and / or treating lung injury, and belongs to the technical field of traditional Chinese medicines. The application of Huangjing polysaccharide in the preparation of products for preventing and / or treating lung injury, wherein the products are drugs or health products. The present application is based on the traditional Chinese medicine theory of treating disease before it occurs, comprehensively analyzes the clinical application characteristics of traditional Chinese medicines in treating lung injury, selects yin-nourishing and qi-tonifying traditional Chinese medicines that enter the lung meridian as the research object, and uses the constructed in-vivo lung injury chemical prevention evaluation system to screen different lung protection activities of Huangjing polysaccharide. Experimental research shows that Huangjing polysaccharide can obviously improve lung injury and has a protective effect on the lung, especially for acute lung injury.

The invention belongs to the technical field of biological medicine, and particularly relates to application of a short peptide entrapped by lung-targeted liposome and used for blocking combination of PKM2-FOXO3A in preparation of a medicine for treating stroke-related lung injury, the amino acid sequence of the short peptide is shown as SEQ ID NO.1, the SEQ ID NO.1 RKGEDREGKR and Pe (at) P-Lipo can be used for remarkably relieving MCAO mouse lung tissue pathological injury, and can be used for preparing a medicine for treating stroke-related lung injury. According to the present invention, with the application of the cerebral ischemia injury in the lung, the total reactive oxygen species (ROS) level in the lung tissue and the mitochondrial ROS level, the reduction of the ATP content can be reversed, the level of the lung tissue inflammation-related protein can be reduced, and the enrichment of PKM2, FOXO3A and TXNIP in the mitochondria can be reduced so as to alleviate the lung tissue oxidative stress and the mitochondrial injury caused by the cerebral ischemia injury, and provide the lung protection effect;

The invention relates to the field of medicines, in particular to application of Noregenin to treatment of acute lung injury or acute respiratory distress syndrome. According to the application disclosed by the invention, NLRP3 inflammasome activation and downstream inflammatory factor release are remarkably reduced by utilizing an inhibition effect of Noregenin on Nur77, so that lung inflammatory response, macrophage proinflammatory polarization and tissue damage in acute lung injury and acute respiratory distress syndrome are effectively relieved; and the pharmaceutical composition shows a definite lung protection effect in various dosage forms and administration modes.

The invention relates to the technical field of biological medicine, in particular to application of procyanidine B2 in preparation of a product for relieving animal lung injury caused by chronic cold exposure. The procyanidine B2 is found to be capable of relieving oxidative stress injury of the lung and enhancing the oxidation resistance of the lung. Technical support is provided for application of procyanidine B2 as a natural lung protection medicine under the condition of chronic cold exposure of animals, and a new thought is provided for comprehensive treatment of animal lung injury caused by chronic cold exposure.