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Isolated organ perfusion pH online monitoring system

A technology for isolated organs and monitoring systems, applied in the field of medical devices, can solve the problems of large pH data detection errors, prevent acidic pH values, and improve perfusion effects

Inactive Publication Date: 2019-12-13
GUANGDONG SHUNDE IND DESIGN INST GUANGDONG SHUNDE INNOVATIVE DESIGN INST +1
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] Based on this, it is necessary to provide an on-line monitoring system for isolated organ perfusion pH in order to solve the problems of hysteresis in the detection of perfusate pH and large pH data detection errors in the traditional perfusion process of isolated organs.

Method used

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Embodiment Construction

[0033] In order to facilitate the understanding of the present application, the present application will be described more fully below with reference to the relevant drawings. A preferred embodiment of the application is shown in the drawings. However, the present application can be embodied in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the disclosure of this application more thorough and comprehensive.

[0034] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the technical field to which this application belongs. The terms used herein in the specification of the application are only for the purpose of describing specific embodiments, and are not intended to limit the application. As used herein, the term "and / or" includes any and all combinations of one or more of the associa...

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Abstract

The invention relates to an isolated organ perfusion pH online monitoring system, which comprises a pH sensor, a pipeline circulation subsystem, buffer solution equipment and a control subsystem. Theinput end of the pipeline circulation subsystem is communicated with the liquid outlet of an isolated organ perfusion system, and the output end of the pipeline circulation subsystem is communicated with the liquid inlet of the isolated organ perfusion system. The buffer solution equipment is used for being communicated with the output end of the pipeline circulation subsystem. The control subsystem is used for driving the pipeline circulation subsystem. The control subsystem is further used for collecting and processing pH data measured by the pH sensor to obtain the pH supplement amount of pH buffer solution and driving the buffer solution equipment to transfer the pH buffer solution to the isolated organ perfusion system based on the pH supplement amount. The pH value of perfusate in the isolated organ perfusion process can be adjusted on line, organ damage caused by slightly acidic perfusate in the isolated organ perfusion process can be prevented, the perfusion effect of isolatedorgans can be improved, and edge donor organs can be saved.

Description

technical field [0001] The present application relates to the technical field of medical devices, in particular to an on-line pH monitoring system for isolated organ perfusion. Background technique [0002] In organ transplantation, the shortage of donor organs severely limits the development of organ transplantation. At present, the organs used for transplantation are mainly donor organs in good condition, and a large number of marginal donor organs are usually discarded. However, the development of in vitro mechanical perfusion (Machine Perfusion, MP) technology makes it possible for marginal donor organs to be used clinically. . [0003] However, long-term perfusion of isolated organs will produce a large number of metabolites, such as water, lactic acid, inorganic salts and urea. During the perfusion of isolated organs, the accumulation of metabolite lactic acid in the isolated organs will make the pH of the perfusate acidic, thus causing damage to the isolated organs....

Claims

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Application Information

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IPC IPC(8): G05D21/00A01N1/02
CPCA01N1/0247G05D21/00
Inventor 唐均匀陈静瑜林祥华卫栋张勃刘峰卢艳袁景泉魏晓磊李伯贵胡艳周鹏刘强毛禹康
Owner GUANGDONG SHUNDE IND DESIGN INST GUANGDONG SHUNDE INNOVATIVE DESIGN INST
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