Anti-wrinkle composition for skin around eyes
A composition and skin technology, applied in the direction of drug combination, skin care preparations, cosmetic preparations, etc., can solve the problems of not obvious anti-wrinkle effect, easy to grow fat particles, poor absorption, etc., to reduce eye puffiness, Irritation-reducing, structural and functional effects
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Embodiment 1
[0134] Example 1 provides an anti-wrinkle composition for skin around the eyes, comprising the following components in parts by weight: 0.1 part of retinoid aldehyde, 0.2 part of complex polypeptide, 0.2 part of white birch extract, 0.2 part of steroid, and 20 parts of solvent ;
[0135] The retinoid aldehyde is a compound of 0.04 part of 3-dehydroretinol and 0.06 part of retinyl palmitate;
[0136] The composite polypeptide is a complex of 0.04 parts of N16 polypeptide, 0.08 parts of myristoyl pentapeptide-17, and 0.08 parts of palmitoyl tetrapeptide-7;
[0137] The preparation method of the N16 polypeptide is:
[0138] (1) Put 2.0g of 2-chlorotrityl chloride resin in the solid-phase synthesis column, process the solid-phase synthesis column with DMF and dichloromethane, add 3.0g tetradiisopropylethylamine, 1.5g methyl sulfide Amino acid, 5.0g benzotriazole-N,N,N',N'-tetramethyluronium hexafluorophosphate, 3.5g 1-hydroxybenzotriazole, 100mL DMF, stirred for 2h, Exclude the...
Embodiment 2
[0152] Example 2 provides an anti-wrinkle composition for skin around the eyes, comprising the following components in parts by weight: 0.5 parts of retinoid aldehyde, 2 parts of compound polypeptide, 5 parts of white birch extract, 1.5 parts of steroid, and 40 parts of solvent ;
[0153] The retinoid aldehyde is a compound of 0.15 parts of 3-dehydroretinol and 0.35 parts of retinyl palmitate;
[0154] The composite polypeptide is a complex of 0.2 parts of N16 polypeptide, 0.8 parts of myristoyl pentapeptide-17, and 1.0 part of palmitoyl tetrapeptide-7;
[0155] The preparation method of the N16 polypeptide is the same as that in Example 1.
[0156] The birch extract is betulin;
[0157] The steroid is cholesta-3,5-diene;
[0158] The solvent is water;
[0159] The preparation method of the anti-wrinkle composition for the skin around the eyes is the same as in Example 1;
[0160] An eye cream, comprising 5 parts of the anti-wrinkle composition for skin around the eyes, 0...
Embodiment 3
[0166] Example 3 provides an anti-wrinkle composition for skin around the eyes, comprising the following components in parts by weight: 0.3 parts of retinoid aldehyde, 1.5 parts of compound polypeptide, 3 parts of white birch extract, 1.2 parts of steroid, and 30 parts of solvent ;
[0167] The retinoid aldehyde is a compound of 0.1 part of 3-dehydroretinol and 0.2 part of retinyl palmitate;
[0168] The composite polypeptide is a complex of 0.24 parts of N16 polypeptide, 0.6 parts of myristoyl pentapeptide-17, and 0.66 parts of palmitoyl tetrapeptide-7;
[0169] The preparation method of the N16 polypeptide is the same as in Example 1;
[0170] The birch extract is betulin;
[0171] The steroid is cholesta-3,5-diene;
[0172] The solvent is water;
[0173] The preparation method of the anti-wrinkle composition for skin around the eyes is the same as in Example 1.
[0174] An eye cream, comprising 2.8 parts of the anti-wrinkle composition for skin around the eyes, 0.3 par...
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