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Skin care emulsion containing cannabidiol (CBD) nanoemulsion, and preparation method of skin care emulsion

A technology of cannabidiol nano and cannabidiol, which is applied in medical preparations containing active ingredients, skin care preparations, skin diseases, etc., can solve low bioavailability, slow medicinal efficacy, and poor transdermal absorption effect To achieve the effect of promoting metabolism, increasing the curative effect of drugs, and maintaining the curative effect of drugs

Inactive Publication Date: 2019-12-27
云南辰锦威生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing cannabidiol skin care milks directly add cannabidiol CBD extract to the formula, which will lead to low drug efficacy, a large loss of active ingredients, low bioavailability, and poor transdermal absorption effect
However, other Chinese herbal skin care milks often have poor transdermal absorption effects, slow or poor medicinal efficacy, and cannot solve problems such as poor skin condition.

Method used

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  • Skin care emulsion containing cannabidiol (CBD) nanoemulsion, and preparation method of skin care emulsion
  • Skin care emulsion containing cannabidiol (CBD) nanoemulsion, and preparation method of skin care emulsion
  • Skin care emulsion containing cannabidiol (CBD) nanoemulsion, and preparation method of skin care emulsion

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] A skin care lotion containing cannabidiol CBD nanoemulsion, prepared through the following steps:

[0040] (1) Prepare materials according to the following mass ratio:

[0041]

[0042]

[0043](1) After fully mixing guar gum and deionized water, place it in a refrigerator at 4°C overnight to fully swell to obtain a swelling liquid, add cholesterol and 1,2-hexanediol, and ultrasonicate in an ice bath at 4°C. The ultrasonic power is 10%, the ultrasonic on time is 5s, the ultrasonic off time is 5s, and the ultrasonic duration is 15min. After the ultrasonic is finished, return to room temperature, add potassium sorbate and CBD nanoemulsion, and stir at a constant temperature of 45°C and 600r / min for 5min. , get material A;

[0044] (2) Mix collagen, urea, silicone, hydrogenated lecithin and appropriate amount of deionized water evenly, stir at 50°C and 500r / min until dissolved, and obtain material B;

[0045] (3) After adding material B in step (2) to material A in...

Embodiment 2

[0056] A skin care lotion containing cannabidiol CBD nanoemulsion, prepared through the following steps:

[0057] (1) Prepare materials according to the following mass ratio:

[0058]

[0059]

[0060] (1) After fully mixing guar gum and deionized water, place it in a refrigerator at 4°C overnight to fully swell to obtain a swelling liquid, add cholesterol and 1,2-hexanediol, and ultrasonicate in an ice bath at 4°C. The ultrasonic power is 15%, the ultrasonic on time is 10s, the ultrasonic off time is 5s, and the ultrasonic duration is 15min. After the ultrasonic is finished, return to room temperature, add potassium sorbate and CBD nanoemulsion, and stir at a constant temperature of 40°C and 400r / min for 10min. , get material A;

[0061] (2) Mix collagen, urea, silicone, hydrogenated lecithin and an appropriate amount of deionized water evenly, stir at 50°C and 300r / min until dissolved, and obtain material B;

[0062] (3) After adding material B in step (2) to materia...

Embodiment 3

[0073] A skin care lotion containing cannabidiol CBD nanoemulsion, prepared through the following steps:

[0074] (1) Prepare materials according to the following mass ratio:

[0075]

[0076]

[0077] (1) After fully mixing guar gum and deionized water, place it in a refrigerator at 4°C overnight to fully swell to obtain a swelling liquid, add cholesterol and 1,2-hexanediol, and ultrasonicate in an ice bath at 4°C. The ultrasonic power is 20%, the ultrasonic on time is 8s, the ultrasonic off time is 5s, and the ultrasonic duration is 10min. After the ultrasonic is finished, return to room temperature, add potassium sorbate and CBD nanoemulsion, and stir at a constant temperature of 50°C and 500r / min for 15min. , get material A;

[0078] (2) Mix collagen, urea, silicone, hydrogenated lecithin and an appropriate amount of deionized water evenly, and stir until dissolved at 65°C and 600r / min to obtain material B;

[0079] (3) After adding material B in step (2) to materi...

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Abstract

The invention provides skin care emulsion containing cannabidiol (CBD) nanoemulsion, and a preparation method of the skin care emulsion. The skin care emulsion is characterized by being prepared fromthe following components in percentage by mass: 10%-50% of CBD nanoemulsion, 0.5%-3% of a seville orange flower extract, 0.5%-3% of a flos gossampini extract, 0.3%-5% of a herba moslae extract, 1%-5%of hydrogenated lecithin, 1%-10% of silicone, 1%-5% of collagen, 1%-8% of carbamide, 0.01%-0.03% of potassium sorbate, 0.01%-0.05% of guar gum, 0.1%-0.5% of cholesterol, 0.5%-3% of 1,2-hexanediol, andthe balance of deionized water, wherein the sum of all the components is 100%. The surface effect and the small size effect of the nanoemulsion are achieved, the solubility of the skin care emulsioncan be changed, the drug efficacy can further be improved, and especially after the CBD nanoemulsion, the seville orange flower extract, the flos gossampini extract and the herba moslae extract are added, through synergy of the effects of skin whitening, inflammation resisting, oxidation resisting and free radical removing of the CBD nanoemulsion, the effects of fading spots, whitening, replenishing water, promoting skin metabolism, timely replenishing nutrients and blocking damage of the external environment to skin are achieved.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to a skin care emulsion containing cannabidiol CBD nanoemulsion and a preparation method thereof. Background technique [0002] With the growth of age, the probability of skin pigmentation also increases significantly. The main manifestations are different spots on the surrounding skin. Although it does not cause pain to people, it affects the appearance to a certain extent. Moreover, as people's pursuit of beauty becomes increasingly fierce, more and more people focus on basic skin care. Among many cosmetics, lotion, as a basic skin care product, is widely used by more people because of its unique advantages. . [0003] Emulsion is a liquid cream cosmetic with good emollient and moisturizing, whitening and antioxidant effects. Soft and shiny, elastic. However, at present, the lotion contains a large amount of chemical components and hormones, and the natural components are few, so the ...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/34A61K8/04A61Q19/08A61P29/00A61Q19/02A61P17/18A61K36/752
CPCA61K8/046A61K8/347A61K8/9789A61K36/185A61K36/53A61K36/752A61K2800/5922A61P17/18A61P29/00A61Q19/02A61Q19/08A61K2300/00
Inventor 李映波冯红宋小雪孙笠雯罗凡雅
Owner 云南辰锦威生物科技有限公司
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