Compound macleaya cordata composition used for treating animal diarrheal diseases

A technology of Boluohui and composition, which is applied in the field of compound Boluohui composition preparation, which can solve problems affecting the clinical efficacy of drugs, achieve the effect of solving the problem of high residues, increasing quality and safety, and improving the efficacy of drugs

Active Publication Date: 2018-01-26
四川吉星动物药业有限公司
View PDF7 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Long-term human consumption of animal foods and Chinese patent medicine health foods containing low concentrations of

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Compound macleaya cordata composition used for treating animal diarrheal diseases
  • Compound macleaya cordata composition used for treating animal diarrheal diseases
  • Compound macleaya cordata composition used for treating animal diarrheal diseases

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0055] Examples 1-10.

[0056] The prescription (5 mL) of compound boluohui injection for treating diarrheal diseases in animals of the present invention is:

[0057] Table 3. Examples 1-10 recipes.

[0058]

[0059] Note: q.s. means appropriate amount, sufficient amount.

[0060] The preparation method includes the following steps.

[0061] (1) Dissolve antioxidant, metal ion chelating agent, bacteriostatic (analgesic) agent and freezing point regulator in water for injection saturated with carbon dioxide or nitrogen, then add quinolones and stir to dissolve.

[0062] (2) Another extraction method of acid extraction, alkali precipitation and alcohol reflux collection is adopted, that is, the fruit pods are taken and returned to the fruit pods, extracted with 20 times the amount of 0.5% acid aqueous solution, and then the pH is adjusted to 8-10 with alkali, and after separation and precipitation, Extracted with 90% ethanol again, the total alkaloids of Bo Luohui can be o...

Example Embodiment

[0064] Examples 11-20.

[0065] The prescription of compound Boluohui injection for treating yellow and white dysentery of piglets of the present invention (emulsion type injection, 100 mL) is as follows.

[0066] Table 4. Examples 11-20 recipes.

[0067]

[0068] Note: q.s. means an appropriate amount, a sufficient amount.

[0069] The preparation method includes the following steps.

[0070] (1) The extraction method of acid extraction and alkali precipitation and alcohol reflux collection is adopted, and the extraction method of acid extraction and alkali precipitation and alcohol reflux collection is adopted, that is, the fruit pods are collected and extracted with 20 times the amount of 0.5% acid aqueous solution, and then Adjust the pH to 8-10 with alkali, and then extract with 90% ethanol after separation and precipitation to obtain the total alkaloids of Boluohui, the extraction rate of which is not less than 60%; (2) Preparation of oil phase: extract Boluohui Th...

Example Embodiment

[0075] Examples 21-30.

[0076] The prescription of compound boluohui injection for treating yellow and white dysentery of piglets of the present invention (suspension injection or sterile powder for injection, 20 mL) is as follows.

[0077] Table 5. Examples 21-30 recipes.

[0078]

[0079] The preparation method includes the following steps.

[0080] (1) The extraction method of acid extraction and alkali precipitation and alcohol reflux collection is adopted, and the extraction method of acid extraction and alkali precipitation and alcohol reflux collection is adopted, that is, the fruit pods are collected and extracted with 20 times the amount of 0.5% acid aqueous solution, and then Adjust the pH to 8-10 with alkali, and then extract with 90% ethanol after separation and precipitation to obtain the total alkaloids of Bo Luohui, the extraction rate of which is not less than 60%.

[0081] (2) Add antioxidant, metal ion chelating agent, bacteriostatic (analgesic) agent, ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a compound macleaya cordata composition used for treating animal diarrheal diseases, and belongs to the field of veterinary drug. The compound macleaya cordata composition contains macleaya cordata total alkaloids extract and quinolone compounds, and contains following active components, by mass, 1 to 1000 parts of macleaya cordata total alkaloids extract, and 1 to 2000 parts of quinolone compounds. The compound macleaya cordata composition can be prepared into solid preparations including liquid preparations such as injections, syrup, and oral solution, tablets, dispersing tablets, sustained release tablets, capsules, particles, and powder, and semi-solid preparations such as ointment, paste, and gel. Obvious synergistic effects are achieved in treatment of animaldiarrheal diseases using the compound macleaya cordata composition, infection of diseases can be controlled effectively, curative effect is obvious, quality is stable, safety is high, the preparationmethod is simple, and the preparation method is suitable for industrialized production.

Description

technical field [0001] The invention relates to a veterinary compound preparation for treating animal diarrhea and its application. It belongs to the field of veterinary medicine. Background technique [0002] "The country is based on the people, and the people depend on food." At present, due to the continuous emergence and mutation of various animal pathogens, the development of my country's livestock and poultry industry has caused serious harm, which has a potential impact on national life and health to a certain extent. A variety of pathogens, such as bacteria, can cause diarrheal diseases in animals. The main target organs of such diseases are the digestive tract and gastrointestinal tract, resulting in impaired nutrient absorption in animals, increased intestinal content, and clinical symptoms such as vomiting, diarrhea, and dehydration. The mortality rate of older animals is extremely high. [0003] Among them, piglet yellow and white scour is a common and frequent...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K36/66A61K47/02A61K47/10A61K47/26A61P1/12A61P31/04A61K31/496A61K31/5383A61K31/4709
Inventor 张凌
Owner 四川吉星动物药业有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap