The invention provides skin care emulsion containing cannabidiol (CBD) nanoemulsion, and a preparation method of the skin care emulsion. The skin care emulsion is characterized by being prepared fromthe following components in percentage by mass: 10%-50% of CBD nanoemulsion, 0.5%-3% of a seville orange flower extract, 0.5%-3% of a flos gossampini extract, 0.3%-5% of a herba moslae extract, 1%-5%of hydrogenated lecithin, 1%-10% of silicone, 1%-5% of collagen, 1%-8% of carbamide, 0.01%-0.03% of potassium sorbate, 0.01%-0.05% of guar gum, 0.1%-0.5% of cholesterol, 0.5%-3% of 1,2-hexanediol, andthe balance of deionized water, wherein the sum of all the components is 100%. The surface effect and the small size effect of the nanoemulsion are achieved, the solubility of the skin care emulsioncan be changed, the drug efficacy can further be improved, and especially after the CBD nanoemulsion, the seville orange flower extract, the flos gossampini extract and the herba moslae extract are added, through synergy of the effects of skin whitening, inflammation resisting, oxidation resisting and free radical removing of the CBD nanoemulsion, the effects of fading spots, whitening, replenishing water, promoting skin metabolism, timely replenishing nutrients and blocking damage of the external environment to skin are achieved.