Protein structure information prediction method, apparatus and device, and storage medium

A technology of structure information and prediction method, which is applied in the field of biological information and can solve the problems of low prediction efficiency of protein structure information and long time consumption of query operation.

Active Publication Date: 2020-01-17
TENCENT TECH (SHENZHEN) CO LTD
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

[0004] However, in the above-mentioned related technologies, in order to extract more accurate sequence features, it is necessary to perform query operations based on large-scale databases, and large-scale databases will cause query operations to take a long time, resulting in protein The prediction efficiency of structural information is low

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  • Protein structure information prediction method, apparatus and device, and storage medium
  • Protein structure information prediction method, apparatus and device, and storage medium
  • Protein structure information prediction method, apparatus and device, and storage medium

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[0050] Reference will now be made in detail to the exemplary embodiments, examples of which are illustrated in the accompanying drawings. When the following description refers to the accompanying drawings, the same numerals in different drawings refer to the same or similar elements unless otherwise indicated. The implementations described in the following exemplary embodiments do not represent all implementations consistent with this application. Rather, they are merely examples of apparatuses and methods consistent with aspects of the present application as recited in the appended claims.

[0051] It should be understood that "several" mentioned herein refers to one or more, and "multiple" refers to two or more. "And / or" describes the association relationship of associated objects, indicating that there may be three types of relationships, for example, A and / or B may indicate: A exists alone, A and B exist simultaneously, and B exists independently. The character " / " gener...

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Abstract

The invention relates to a protein structure information prediction method, apparatus and device, and a storage medium, and relates to the technical field of biological information. The method comprises the following steps of: obtaining multi-sequence alignment data by performing sequence alignment query for an amino acid sequence of protein in a first database; performing feature extraction on the multi-sequence alignment data; after obtaining initial sequence features, processing the initial sequence features by a sequence feature amplification model to obtain amplification sequence featuresof the protein; and predicting structural information of the protein according to the amplification sequence features. According to the scheme, when the structural information of the protein is predicted based on artificial intelligence, the prediction efficiency of the structural information of the protein can be improved under the condition of ensuring the prediction accuracy of the structuralinformation of the protein.

Description

technical field [0001] The present application relates to the field of biological information technology, in particular to a protein structure information prediction method, device, equipment and storage medium. Background technique [0002] The actual function of protein in organisms is closely related to its three-dimensional structure. Therefore, it is of great significance to accurately determine the three-dimensional structure of protein. [0003] Since the three-dimensional structure of a protein is essentially determined by its corresponding amino acid sequence information, in related technologies, the protein structure information can be determined through the amino acid sequence of the protein. For example, when determining the structural information of a protein based on the amino acid sequence of the protein, firstly, according to the amino acid sequence of the protein, a multi-sequence alignment data query operation is performed in an amino acid sequence database...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16B5/00G16B15/00G16B50/00
CPCG16B5/00G16B15/00G16B50/00G16B15/20G16B50/30G16B40/20G16B30/10G16B20/30
Inventor 吴家祥郭宇智黄俊洲
Owner TENCENT TECH (SHENZHEN) CO LTD
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