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Application of longan shell extract for preparing compositions regulating and controlling SREBP-1c, ACC and SCD-1 protein

A technology of SCD-1, longan shell, applied in the direction of drug combination, medical preparations containing active ingredients, food science, etc., can solve a large number of longan shell by-products and other problems, achieve liver protection, inhibit lipogenesis, reduce GPT index Effect

Inactive Publication Date: 2020-02-14
百岳特生物技术(上海)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, after longan is processed, a large number of longan shell by-products will be produced

Method used

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  • Application of longan shell extract for preparing compositions regulating and controlling SREBP-1c, ACC and SCD-1 protein
  • Application of longan shell extract for preparing compositions regulating and controlling SREBP-1c, ACC and SCD-1 protein
  • Application of longan shell extract for preparing compositions regulating and controlling SREBP-1c, ACC and SCD-1 protein

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Embodiment Construction

[0016] The invention provides the use of a longan shell extract for preparing a composition regulating SREBP-1c, ACC and SCD-1 protein. The longan shell extract of the present invention is extracted at different temperatures, and the longan shell is extracted with a solvent Obtained by extraction and centrifugation, it can be used to inhibit the formation of fatty liver, prevent liver damage, reduce the value of GTP (glutamate pyruvatetransaminase) and reduce the genes related to the synthesis of liver fat.

[0017] The longan shell extract of the present invention is obtained by an extraction method, and the extraction method comprises the following steps: (a) extracting the longan shell with an extraction solvent, wherein the extraction is carried out at 50-100°C, and the extraction solvent The volume ratio to the longan shell is 5-20: 1-5; (b) the obtained product is centrifuged; (c) the centrifuged supernatant is filtered to obtain a filtrate; (d) the filtrate is heated at ...

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Abstract

The invention relates to applications of longan shell extract, and especially relates to an application of a longan shell extract for preparing composition regulating and controlling SREBP-1c, ACC andSCD-1 protein. The application of the longan shell extract for preparing the composition which can reduce the expression of the SREBP-1c, ACC and SCD-1 protein is provided, wherein the longan shell extract is obtained through the extraction of water, alcohol or hydroalcoholic solvents. The longan shell extract can significantly inhibit the generation of fat, reduce GPT index and protect the liver.

Description

technical field [0001] The present invention relates to the use of the longan shell extract, in particular to the use of the longan shell extract for preparing a composition regulating SREBP-1c, ACC and SCD-1 proteins. Background technique [0002] The causes of liver disease among the Taiwanese population include viral infection, drug abuse, and long-term alcoholism. According to the 2015 statistics from the Department of Health of the Taiwan Executive Yuan, liver diseases such as chronic liver disease and cirrhosis rank tenth among the top ten causes of death in Taiwan. [0003] In recent years, the consumption of alcoholic beverages in Taiwan has increased significantly, and the incidence of alcoholic liver disease has also increased relatively. After long-term alcohol intake, the biochemical and pathological damage caused in the human body is very complex, and the most deeply affected tissue is the main tissue of alcohol metabolism-the liver. Liver damage caused by lon...

Claims

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Application Information

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IPC IPC(8): A61K36/77A61P1/16A23L33/17A61K131/00
CPCA61K36/77A23L33/17A61P1/16
Inventor 林咏翔陈怡卉甘恺雯
Owner 百岳特生物技术(上海)有限公司