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External preparation for treating leuconychia and preparation method thereof

A technology of onychomycosis and medicament, which is applied in the field of external medicament for the treatment of onychomycosis and its preparation, which can solve the problems of long treatment period of external medicament, need to improve the cure rate, and severe pain, so as to shorten the treatment cycle and shorten the treatment cycle , to avoid the effect of allergies

Inactive Publication Date: 2020-02-25
安徽世龙生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the preparation process of the external medicament requires heating and decocting, which takes a long time and wastes energy; the external medicament has a long treatment cycle, and the cure rate still needs to be improved; there is severe pain during the process of removing nails.

Method used

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  • External preparation for treating leuconychia and preparation method thereof
  • External preparation for treating leuconychia and preparation method thereof
  • External preparation for treating leuconychia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Embodiment 1: the preparation of A cream

[0042] The ratio of each raw material is as follows:

[0043] raw material name parts by mass mass (g) Clove Basil Oil 3％ 3 sodium sulfide 3％ 3 urea 8％ 8 Tween 80 5％ 5 vaseline 3％ 3 stearic acid 4％ 4 Fatty alcohol polyoxyethylene ether 3％ 3 glycerin 3％ 3 Edetate Disodium 0.5％ 0.5 purified water 67.5％ 67.5

[0044] Preparation:

[0045] (1) Water item: heat the purified water to 90°C, keep the temperature constant for half an hour, add glycerin and disodium edetate, and stir well;

[0046] (2) Oil item: heat fatty alcohol polyoxyethylene ether, stearic acid, vaseline, and Tween 80 to 90°C at the same time, keep the temperature constant for half an hour, add clove basil oil and stir evenly;

[0047] (3) Pump the water item obtained in step (1) into the emulsification tank through the vacuum pump, then pump the oil item obtained in the step (...

Embodiment 2

[0049] Embodiment 2: the preparation of A cream

[0050] The ratio of each raw material is as follows:

[0051]

[0052]

[0053] Preparation:

[0054] (1) Water item: heat the purified water to 90°C, keep the temperature constant for half an hour, add glycerin and disodium edetate, and stir well;

[0055] (2) Oil item: heat fatty alcohol polyoxyethylene ether, stearic acid, vaseline, and Tween 80 to 90°C at the same time, keep the temperature constant for half an hour, add clove basil oil and stir evenly;

[0056] (3) Pump the water item obtained in step (1) into the emulsification tank through the vacuum pump, then pump the oil item obtained in the step (2) into the emulsification tank through the vacuum pump, extract the air in the emulsification tank, and start to Stir at 40-45 minutes per minute, and at the same time pass in cooling water for emulsification;

[0057] (4) When the emulsification drops to 60°C, add urea and sodium sulfide, and keep stirring until a...

Embodiment 3

[0058] Embodiment 3: the preparation of A cream

[0059]

[0060]

[0061] Preparation:

[0062] (1) Water item: heat the purified water to 90°C, keep the temperature constant for half an hour, add glycerin and disodium edetate, and stir well;

[0063] (2) Oil item: heat fatty alcohol polyoxyethylene ether, stearic acid, vaseline, and Tween 80 to 90°C at the same time, keep the temperature constant for half an hour, add clove basil oil and stir evenly;

[0064] (3) Pump the water item obtained in step (1) into the emulsification tank through the vacuum pump, then pump the oil item obtained in the step (2) into the emulsification tank through the vacuum pump, extract the air in the emulsification tank, and start to Stir at 40-45 minutes per minute, and at the same time pass in cooling water for emulsification;

[0065] (4) When the emulsification drops to 60°C, add urea and sodium sulfide, and keep stirring until a paste is formed.

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PUM

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Abstract

The invention belongs to the technical field of medicines, and particularly relates to an external preparation for treating leuconychia and a preparation method thereof. The external preparation comprises two or more than two of an ointment A, a gel B and liquid C, and the treatment period of the external preparation is short; the preparation process is simple, the steps of heating, water circulation and the like are not needed, energy conservation and emission reduction are achieved, and industrialization is easy to achieve; loss of effective components and nutrition of the traditional Chinese medicines is effectively prevented in the preparation process; the treatment period is greatly shortened; the cure rate is increased, and recurrence is avoided after curing.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an external medicament for treating onychomycosis and a preparation method thereof. Background technique [0002] Onychomycosis, commonly known as "onychomycosis", is often caused by various fungi such as Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton flocculus. A few are caused by other filamentous fungi and yeasts. In severe cases, the nail plate can be deformed, thickened, hollow, and brittle. If it takes a long time, it can lead to nail bed atrophy, osteomyelitis, etc. Moreover, the fungi are highly contagious and can be transmitted to family members or friends around them through direct or indirect contact, often bringing physical and mental pain to patients in life and work. [0003] Chinese patent CN1319563C discloses a kind of external medicament for treating onychomycosis, which is composed of A paste, B paste and C liquid, wherein, A...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/53A61K38/39A61K36/808A61K9/06A61P17/00A61P31/10A61K31/17A61K36/886A61K36/896
CPCA61K9/0014A61K9/06A61K31/17A61K36/15A61K36/185A61K36/53A61K36/808A61K36/886A61K36/896A61K38/39A61K47/12A61K47/183A61K2236/333A61P17/00A61P31/10A61K2300/00
Inventor 汪世龙
Owner 安徽世龙生物医药科技有限公司
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