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A method for measuring the similarity of retinal vascular networks based on topology and atlas

A retinal blood vessel and topology technology, applied in the field of target feature description and comparison, can solve problems such as poor accuracy and insufficient information, and achieve the effect of improving accuracy and similarity

Active Publication Date: 2021-10-29
BEIJING INSTITUTE OF TECHNOLOGYGY
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Problems solved by technology

[0004] The purpose of the present invention is to propose a method for measuring the similarity of the retinal vascular network based on topological structure and atlas in view of the technical defects such as poor accuracy and insufficient information in the existing methods for measuring the similarity of the retinal vascular network

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  • A method for measuring the similarity of retinal vascular networks based on topology and atlas
  • A method for measuring the similarity of retinal vascular networks based on topology and atlas
  • A method for measuring the similarity of retinal vascular networks based on topology and atlas

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Embodiment 1

[0060] figure 1 It is a flow chart of the method for measuring the similarity of the retinal vascular network in a specific embodiment of the present invention, specifically comprising the following steps:

[0061] Step A: Retinal blood vessel tracking; select two color fundus images provided by Beijing Anzhen Hospital as the samples to be compared, named picture a and picture b respectively, and compare the similarity of the two blood vessel networks; Track and measure relevant parameters, including the following sub-steps:

[0062] Step A.1: For the two color fundus images a and b for similarity comparison, respectively determine the center of the optic disc and the radius of the optic disc;

[0063] Step A.2: Determine the tracking starting position of each vascular tree at k times the radius of the optic disc from the center of the optic disc, where k is set to 1.5;

[0064] Step A.3: Carry out blood vessel tracking from the starting position, determine the topological s...

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Abstract

The invention relates to a method for measuring the similarity of a retinal blood vessel network based on a topological structure and an atlas, and belongs to the technical field of target feature description and comparison. It includes the following steps: Step 1: retinal blood vessel tracking; Step 2: Calculate the topological distance between the vascular trees, that is, the tree edit distance, and match the vascular trees accordingly to generate a matched vascular tree pair; Step 3: Calculate the distance between the vascular trees The spectral distance between each pair of vascular trees matched in step 2 is sampled, and then the sampled data is spectrally mapped, and the spectral distance of the pair of vascular trees is calculated according to the spectrally mapped data; step 4: weighted integration topology distance and spectral distance. The method compares vascular parameters of vascular trees with similar topological geometric shapes through local vascular tree matching, and realizes a more accurate measurement of the similarity of vascular networks; uses the clustering characteristics of spectral mapping to make the parameter differences of vascular trees more obvious , effectively improving the accuracy of similarity measurement.

Description

technical field [0001] The invention relates to a method for measuring the similarity of a retinal blood vessel network based on a topological structure and an atlas, and belongs to the technical field of target feature description and comparison. Background technique [0002] The retinal vascular network is the only blood circulation system in the human body that can be observed non-immersively, which can provide a lot of meaningful medical research information. The morphological changes of retinal blood vessels are related to many major diseases, such as hypertension and diabetes. By observing the changes of the retinal vascular morphology and parameters in the same patient, the correlation between the disease and the vascular morphology and parameters can be analyzed; by comparing the differences in the retinal vascular morphology and parameters of different patients, it can assist doctors in diagnosing the disease and the extent of the disease. Therefore, it is of great...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T7/00G06K9/62G16H50/20
CPCG06T7/0012G16H50/20G06T2207/10024G06T2207/30041G06T2207/30101G06F18/22
Inventor 李慧琦吴冠男
Owner BEIJING INSTITUTE OF TECHNOLOGYGY
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