Composition having bacterium resisting effects and application of composition having bacterium resisting effects to additive-free skin care products

A technology of antibacterial effect and composition, applied in the field of compositions with antibacterial effect, can solve problems such as sensitization, carcinogenesis, skin aging, etc., and achieve long shelf life, avoid potential harm, and good antibacterial and bacteriostatic effects.

Pending Publication Date: 2020-03-27
湖州中科金羿医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Long-term use of traditional preservatives has adverse effects on human skin. For example, formaldehyde and formaldehyde donors have the risk of

Method used

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  • Composition having bacterium resisting effects and application of composition having bacterium resisting effects to additive-free skin care products
  • Composition having bacterium resisting effects and application of composition having bacterium resisting effects to additive-free skin care products
  • Composition having bacterium resisting effects and application of composition having bacterium resisting effects to additive-free skin care products

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] A composition with antibacterial effect, by parts by weight, comprising the following components:

[0032]

[0033] The molecular weight of the polylysine is 3900-4000.

[0034] The cordycepin is derived from the extract of Cordyceps sinensis.

[0035] The pH regulator is citric acid.

[0036] A preparation method of a composition with antibacterial effect, comprising the following steps:

[0037] (1) Weigh each component according to the formula amount, add a pH regulator into water, adjust the pH to 5.2, and prepare mixture A for subsequent use;

[0038] (2) Mix p-hydroxyacetophenone and 1,2-hexanediol, heat up to 40°C, stir, then cool down to 30°C to prepare mixture B, set aside;

[0039] (3) Add the mixture B prepared in step (2) to the mixture A prepared in step (1), stir evenly, then add nisin, polylysine, cordycepin, lysozyme, stir and dissolve until the prepared The mixture is transparent, that is, a composition with antibacterial effect is obtained.

Embodiment 2

[0041] A composition with antibacterial effect, by parts by weight, comprising the following components:

[0042]

[0043] The molecular weight of the polylysine is 4000-4100.

[0044] The cordycepin is derived from the extract of Cordyceps sinensis.

[0045] The pH regulator is citric acid.

[0046] A preparation method of a composition with antibacterial effect, comprising the following steps:

[0047] (1) Weigh each component according to the formula amount, add a pH regulator into water, adjust the pH to 5.5, and prepare mixture A for subsequent use;

[0048] (2) Mix p-hydroxyacetophenone and 1,2-hexanediol, heat up to 42°C, stir, then cool down to 25°C to prepare mixture B, set aside;

[0049] (3) Add the mixture B prepared in step (2) to the mixture A prepared in step (1), stir evenly, then add nisin, polylysine, cordycepin, lysozyme, stir and dissolve until the prepared The mixture is transparent, that is, a composition with antibacterial effect is obtained.

Embodiment 3

[0051] A composition with antibacterial effect, by parts by weight, comprising the following components:

[0052]

[0053]

[0054] The molecular weight of the polylysine is 4100-4200.

[0055] The cordycepin is derived from the extract of Cordyceps sinensis.

[0056] The pH regulator is citric acid.

[0057] A preparation method of a composition with antibacterial effect, comprising the following steps:

[0058] (1) Weigh each component according to the formula amount, add the pH regulator into water, adjust the pH to 5.8, and prepare the mixture A, set aside;

[0059] (2) Mix p-hydroxyacetophenone and 1,2-hexanediol, heat up to 45°C, stir, and then cool down to 30°C to prepare mixture B for later use;

[0060] (3) Add the mixture B prepared in step (2) to the mixture A prepared in step (1), stir evenly, then add nisin, polylysine, cordycepin, lysozyme, stir and dissolve until the prepared The mixture is transparent, that is, a composition with antibacterial effect ...

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Abstract

The invention belongs to the field of cosmetics, and discloses a composition having bacterium resisting effects. The composition having bacterium resisting effects comprises the following components of 0.001-8 parts of nisin, 0.001-5 parts of polylysine, 0.001-5 parts of cordycepin, 0.001-2 parts of lysozyme, 0.1-20 parts of 1,2-hexanediol, 0.01-1 part of p-phydroxyacetophenone, 60-90 parts of water and 0.1-5 parts of a pH regulator. Compared with the prior art, the prepared composition has the advantages that through appropriate selection of the nisin, the polylysine and the cordycepin and appropriate selection of consumption, the prepared composition has favorable effects of resisting bacteria and restraining bacteria, and particularly has excellent effects of resisting bacteria and restraining bacteria on heat-resisting coliform, pseudomonas aeruginosa, streptococcus albus, aspergillus niger and microzyme, so that the composition can replace a traditional preservative when being applied to the skin care products to avoid potential damage to skin by a conventional preservative and improve the safety of the products.

Description

technical field [0001] The invention belongs to the field of cosmetics, in particular to a composition with antibacterial effect and its application in additive-free skin care products. Background technique [0002] In the field of cosmetics, formulators add preservatives in order to inhibit the growth and reproduction of microorganisms in cosmetics and prolong the shelf life of cosmetics. Traditional preservatives are divided into the following categories, formaldehyde and formaldehyde donors, parabens, isothiazolinones, phenols and acids, etc. Long-term use of traditional preservatives has adverse effects on human skin. For example, formaldehyde and formaldehyde donors have the risk of carcinogenicity, paraben esters may react with ultraviolet rays and cause skin aging, and isothiazolinones have the risk of sensitization, etc. . How to reduce or even not use these preservatives, avoid potential hazards and worries, and at the same time ensure the shelf life of cosmetics ...

Claims

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Application Information

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IPC IPC(8): A61K8/9728A61K8/88A61K8/66A61K8/64A61K8/34A61Q17/00A61Q19/00
CPCA61K8/9728A61K8/88A61K8/66A61K8/64A61K8/345A61Q19/00A61Q17/005A61K2800/524
Inventor 周守山戴稳平肖炼林晓何俭邝刘建李盈王伟邹劲峰
Owner 湖州中科金羿医药科技有限公司
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