15 results about "P-hydroxyacetophenone" patented technology

This invention relates to a highly penetrating soluble microneedle patch containing small molecule PDRN. It comprises a functional needle body and a base. The functional needle body is prepared from components comprising the following parts by weight: 4-7 parts sodium hyaluronate, 1-3 parts PDRN, 1-2 parts p-hydroxyacetophenone, 1-3 parts hydroxypropyl cellulose, 2-4 parts glutathione, 0.1-0.3 parts tranexamic acid, and 5-7 parts centella asiatica. The base is prepared from a polymer matrix material. This invention is the first to add PDRN to a soluble microneedle patch, using PDRN of different molecular weights and concentrations to prepare soluble microneedle patches with different penetration properties. This effectively solves the problems of insufficient hardness, poor penetration, and poor penetration rate of existing soluble microneedle patches, enabling it to penetrate skin with different stratum corneum thicknesses and making it applicable to various skin conditions with a wide range of applications.

This invention belongs to the field of cosmetic raw material technology, and particularly relates to a preservative and antibacterial composition, its preparation method, and its application. The preservative and antibacterial composition comprises the following components in weight percentages: 10-30% antimicrobial lipopeptide, 0.1-1% lysozyme, 0.01-0.05% capryloyl hydroxamic acid, 0.2-0.6% p-hydroxyacetophenone, and the balance being water. This invention screens and extracts natural compounds with antibacterial and preservative activities—antimicrobial lipopeptides and natural antimicrobial substances—lysozyme from natural microbial sources, and combines them with two chemical preservatives, capryloyl hydroxamic acid and p-hydroxyacetophenone, to prepare a novel preservative and antibacterial composition. This compounding method significantly reduces the amount of chemical preservatives used, thereby ensuring the safety and low toxicity of the composition. Furthermore, the components work synergistically to further enhance the preservative and antibacterial properties of the composition.

This invention relates to the field of food preservation technology, specifically to a nano-zinc oxide-chitosan composite food preservation coating and its preparation method. The coating comprises quinone-imine cross-linked modified chitosan, p-hydroxyacetophenone, nano-zinc oxide, glycerol, sodium citrate, ascorbic acid, potassium sorbate, and deionized water. By introducing a quinone-imine cross-linking structure into the chitosan molecules, the density and stability of the film are improved; further, the introduction of p-hydroxyacetophenone to generate hydrogen bonds and π-π interactions with the modified chitosan enhances intermolecular forces and promotes the uniform dispersion of nano-zinc oxide. The coating obtained through optimized process conditions exhibits high transparency, good mechanical strength and toughness, and significantly improved inhibition zone diameter and antioxidant capacity. This invention, through the synergistic effect of quinone-imine cross-linking modification and small molecules, achieves a comprehensive improvement in the transparency, stability, and antibacterial durability of the coating, demonstrating outstanding inventiveness and application value.

The application discloses a kind of composite active peptide hydrogel eye mask and preparation method thereof, it is related to hydrogel technical field.The composite active peptide hydrogel eye mask includes specific proportion water, glycerol, butanediol, gelling agent combination, 0.35-0.6% of p-hydroxyacetophenone, 0.5-1% of 1,2-hexanediol, hyaluronic acid derivative combination, 0.05-0.2% of potassium chloride, 0.05-0.2% of sodium heparin and polypeptide combination, when preparing, through three-stage low-temperature temperature control process, keep excellent formula biological macromolecule and other natural, green harmless ingredients, safe and harmless to human body, the product of the present application scheme solves the problems, such as poor adhesion of existing hydrogel eye mask, low active ingredient penetration rate, polypeptide high temperature inactivation and water retention deficiency, high strength and high adhesion of hydrogel composition, can make eye mask carrier and eye skin closely adhere, realize closely skin without sliding, polypeptide transdermal absorption rate is improved, active ingredient stability is maintained, composite active peptide has high affinity to human body and is beneficial to skin absorption, has significant advantages in the aspect of soothing wrinkle generation.

The present application provides a dandruff-removing and itching-relieving essence liquid with anti-inflammatory and antibacterial effects, and relates to the field of cosmetics.The present application provides an essence liquid, components of which comprise spironolactone, 1,2-hexanediol, ethanol, propylene glycol, butanediol, p-hydroxyacetophenone, citric acid, sodium citrate, pyridoxine hydrochloride, sophora alkaloid, menthol lactate, PEG-40 hydrogenated castor oil, dipotassium glycyrrhizinate, sodium hyaluronate, essence and quaternary ammonium salt-73; the essence liquid has significant anti-inflammatory and itching-relieving effects when used for scalp care, and also has antibacterial and dandruff-removing effects, and has great application potential in the field of cosmetics.

This invention discloses a skin repair dressing containing ectoine and its preparation method, relating to the field of skin care technology. By weight, it comprises the following components: ectoine: 2-5 parts, panthenol: 1-3 parts, sodium hyaluronate: 0.05-0.1 parts, glycerin: 5.0-8.0 parts, trehalose: 0.5-1.5 parts, squalane: 3.0-5.0 parts, caprylic / capric triglyceride: 4.0-6.0 parts, cetyl ethylhexanoate: 3.0-5.0 parts, Montanov L: 2.0-4.0 parts, carbomer: 0.1-0.3 parts, and p-hydroxyethylhexanoate. Acetophenone: 0.3-0.5 parts, 1,2-hexanediol: 0.8-1.2 parts, triethanolamine: 0.1-0.3 parts, polyhexamethylene biguanide (PHMB): 0.01-0.03 parts, ceramide: 0.05-0.1 parts, with purified water as the balance, and the total weight of all components is 100 parts. This invention combines active ingredients such as ectoine to repair the skin in multiple dimensions, is suitable for various skin types, and adds antibacterial ingredients to make the effect more lasting. Standardized preparation process is adopted to control the parameters of each step, ensuring uniform and stable dressing, ensuring hygiene and safety, and achieving stable product quality and consistent effect.

This invention belongs to the field of dressing preparation technology, specifically relating to a mussel protein dressing with anti-inflammatory, antibacterial, moisturizing, repairing, and wound-healing effects, and its preparation method. The invention comprises the following raw materials by weight: 15-25 parts mussel adhesive protein ferment, 2-5 parts reed extract, 6-10 parts geranium extract, 4-8 parts mannitol, 10-15 parts glycerin, 0.6-1 part sodium chloride, 0.2-0.5 parts p-hydroxyacetophenone, 1-2 parts 1,2-hexanediol, 0.05-0.1 parts ectoine, and 100-200 parts water. This invention utilizes a specific combination of mussel adhesive protein ferment, reed extract, and geranium extract to facilitate the synergistic effect of each active substance and fully release its efficacy. Therefore, the technical solution of this invention has the advantages of more comprehensive functions and more significant effects, enabling anti-inflammatory, antibacterial, moisturizing, repairing, and wound-healing effects.

This invention provides a method for synthesizing p-hydroxyacetophenone, comprising the following steps: simultaneously introducing phenyl acetate and a solution containing anhydrous hydrogen fluoride into a microchannel reactor to carry out a rearrangement reaction, wherein the rearrangement reaction is carried out at a temperature of 40-140°C and a pressure of 1-2 MPa, to obtain crude p-hydroxyacetophenone. This invention helps to improve the conversion rate of phenyl acetate and the selectivity of p-hydroxyacetophenone.

This invention provides a method for synthesizing p-hydroxyacetophenone, comprising the following steps: introducing a solution containing anhydrous hydrogen fluoride into a reaction vessel containing phenyl acetate to carry out a rearrangement reaction, wherein the rearrangement reaction is carried out at a temperature of 80-140°C and a pressure of 1-2 MPa, to obtain crude p-hydroxyacetophenone. This invention helps to improve the conversion rate of phenyl acetate and the purity of p-hydroxyacetophenone.

This invention discloses a perming composition based on thermosensitive regulation, comprising the following components: an aqueous phase including disodium EDTA, urea, glycerin, methylparaben, propylparaben, and phenoxyethanol; a reducing buffer phase including cysteine ​​hydrochloride, cysteine, sodium bicarbonate, ammonium carbonate, and ammonia; an emulsified oil phase including caprylic / capric triglyceride, polydimethylsiloxane, sodium lauroyl glutamate, cocamidopropyl betaine, and PEG-40 hydrogenated castor oil; an active repair phase including phosphatidylcholine, hydrogenated lecithin, ceramide, tocopherol, ascorbyl palmitate, ethoxydiethylene glycol, p-hydroxyacetophenone, and 1,2-hexanediol; a conditioning and repair phase including hydrolyzed keratin, arginine, methylisothiazolinone, and a daily fragrance; and the remainder being deionized water. This invention simplifies the judgment and operation process of softening through the synergistic effect of thermosensitive regulation and the cysteine-based reducing system. This invention also includes a method for preparing the perming composition.

The application provides a powder foundation and a preparation method thereof, and relates to the field of cosmetics, and comprises the following steps: crushing and mixing a filler, a titanium dioxide colorant, an inorganic colorant, an adsorbent and a film-forming agent, and sieving to obtain a powder phase; adding deionized water and glycerol into a container 1, stirring to form a vortex, keeping the rotating speed, and then adding carbomer 940 powder at the edge of the vortex; after the powder is added, the rotating speed is increased to stir until the powder is completely dispersed; after stirring and swelling, tromethamine solution is added while stirring until a hydrogel is formed; after the gel is formed, the rotating speed is reduced and continuous stirring is performed; butanediol, 1,2 pentanediol and p-hydroxyacetophenone are added into a container 2 and dissolved, and then the hydrogel is added and stirred; the powder phase is added into the container 2, stirred and discharged, and then sieved through a 20-mesh sieve; after sieving, the material is poured into the container 2, stirred, discharged and sieved through a 40-mesh sieve. The application is a two-in-one product of a loose powder and a foundation, and a user can complete the foundation makeup by pressing and applying.

This invention discloses a skincare gel for multi-functional synergistic repair of sun damage and its preparation process, relating to the field of cosmetic technology. The method is as follows: Loofah fermentation broth is prepared under sterile conditions; allantoin, *Alternaria alterniflora* fermentation product extract, aloe vera gel, and panthenol are added to the loofah fermentation broth and stirred to dissolve, obtaining mixture A; sodium polyacrylamide dimethyl taurate and trehalose are dry-mixed and sprinkled into mixture A, followed by the addition of sugar isomers, p-hydroxyacetophenone, and water-soluble silica elastomers. After standing and swelling, homogenization is performed to obtain mixture B; Phalaenopsis orchid extract and menthol lactate are added dropwise to mixture B, followed by the addition of Centella asiatica extract, and mixed to obtain mixture C. The mixture is then degassed under vacuum and allowed to stand to defoam, yielding the skincare gel. This invention achieves four effects—immediate soothing, anti-inflammatory and antioxidant, barrier repair, and microecological stabilization—through multi-dimensional ingredient synergy, rapidly and effectively repairing sun damage in the long term, and solving the problem of insufficient synergy between various functional ingredients.

This invention discloses a skin repair dressing containing Pro-Xylane and its preparation method, relating to the field of skin care technology. By weight, it comprises the following components: Pro-Xylane: 0.8-1.2 parts, Sodium hyaluronate: 0.05-0.1 parts, Glycerin: 6.0-10.0 parts, Carbomer: 0.2-0.4 parts, Trehalose: 0.8-1.2 parts, p-hydroxyacetophenone: 0.3-0.5 parts, Caprylic / Capric triglyceride: 4.0-6.0 parts, Montanov L: 2.5-3.5 parts, Cetyl ethylhexanoate: 4.5 parts. The total weight of the components is 100 parts: 5.5 parts squalane, 2.5-3.5 parts 1,2-hexanediol, 0.8-1.2 parts triethanolamine, and the remainder is purified water. This invention creates a dressing system suitable for skin repair, combining active ingredients and functional excipients. Multiple components work synergistically to balance efficacy and skin feel, adapting to various skin repair conditions. At the same time, a standardized preparation process is designed to control parameters at each stage, ensuring uniformity and stability of each phase, protecting active ingredients, removing impurities and ensuring sterility, thereby improving product safety and stability.