A rotating lensless pixel super-resolution imaging system and imaging method thereof
An imaging method and imaging system technology, applied in microscopes, analysis of materials, material analysis by optical means, etc., can solve the problems of high cost and burden, inconvenient integration and commercialization, and achieve low manufacturing and maintenance costs and low costs. , The effect of improving the level of medical testing technology
Active Publication Date: 2020-12-22
PEKING UNIV
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[0004] In terms of improving resolution, the current pixel super-resolution method requires a high-precision translation stage to move the sample by a sub-pixel displacement distance, which will bring higher costs and burdens to the experiment, and is not easy for integration and commercialization.
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[0032] The present invention will be further elaborated below through specific embodiments in conjunction with the accompanying drawings.
[0033] Such as figure 1 As shown, the rotating lensless pixel super-resolution imaging system of this embodiment includes: an illumination source 1, an optical filter 2, a lens 3, an optical fiber 4, a rotating stage, an area array detector, and a computer; wherein, the illumination source emits illumination Light, the illumination light is partially coherent light; the illumination light is filtered by the optical filter 2, converged by the lens 3 and meets the sample 0 by the optical fiber 4, a part of which is scattered, and the other part is directly transmitted through the sample and continues to propagate; the scattered light and The transmitted light interferes on the receiving surface of the area array detector; the area array detector collects the original interference image and transmits it to the computer for storage; the sample...
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The invention discloses a rotary lensless pixel super-resolution imaging system and an imaging method thereof. According to the invention, the length of a diagonal line in a frequency domain is twiceof the side length, and information in a space frequency domain in the diagonal line is the multiple of information in the horizontal and vertical directions; frequency domain images at all angles areobtained through relative rotation of a sample and an area array detector, the frequency domain images at all angles are spliced, extracted and fused, and a spatial domain is returned to so as to obtain a pixel super-resolution image. The system is simple, low in manufacturing and maintenance cost and easy to operate; the image resolution can be improved only by rotating the objective table for multiple times of measurement; and the realization of a miniaturized, low-cost and portable microscopic imaging detection system is facilitated, and the medical detection technical level of a condition-limited region is effectively improved.
Description
technical field [0001] The invention relates to lensless microscopy technology, in particular to a rotating lensless pixel super-resolution imaging system and an imaging method thereof. Background technique [0002] Lens-free microscopy is a digital microscopy technique that does not require a lens for imaging. Based on the principle of Gabor coaxial holography, it uses an area array detector to collect the original hologram, and then reconstructs the sample through digital image processing technology, so as to realize digital microscopic imaging. The resulting resolution of traditional lensless techniques is limited by the photodetector pixel size, which is close to the pixel size. [0003] Nowadays, there have been many reports on lensless microscopy, and the focus of attention is nothing more than how to obtain higher-resolution images faster: in terms of resolution improvement, the pixel super-resolution method represented by sub-pixel displacement; In terms of process...
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IPC IPC(8): G01N21/84G02B21/36G02B27/58
CPCG01N21/84G02B21/361G02B21/367G02B27/58
Inventor 席鹏姜杉
Owner PEKING UNIV