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Screening method and application of serum metabolic markers for combined diagnosis of low bone density in laying hens

A technology of metabolic markers and bone mineral density is applied in the combined diagnosis of low bone density of laying hens and the detection of serum metabolic markers, and the screening of serum metabolic markers of combined diagnosis of low bone density of laying hens. Large impact, prone to fractures and other problems, to achieve the effect of improving animal welfare and economic benefits

Active Publication Date: 2021-02-26
HUAZHONG AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Osteoporosis in caged laying hens has a greater impact on laying hens. On average, laying hens are artificially inseminated once every 5-6 days. Every time they grab the legs of breeders for artificial insemination, it is very easy to cause fractures in laying hens. Complete loss of seed performance
In addition, when layer hens suffer from osteoporosis, they are not only prone to fractures, but the quality of eggshells in the middle and late stages of egg production will also drop significantly, resulting in a significant increase in egg breaking rate, as well as a decrease in egg production rate and an increase in the death rate. huge economic losses to the industry
[0003] Many methods have been applied to the prevention and control of osteoporosis in caged layer hens, such as nutritional regulation, strengthening exercise and drug treatment, etc., but these methods have not yet achieved satisfactory results
Osteoporosis in caged laying hens has no obvious characteristic changes before the onset, and it is difficult to return to normal levels after the onset

Method used

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  • Screening method and application of serum metabolic markers for combined diagnosis of low bone density in laying hens
  • Screening method and application of serum metabolic markers for combined diagnosis of low bone density in laying hens
  • Screening method and application of serum metabolic markers for combined diagnosis of low bone density in laying hens

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Embodiment 1

[0030] Example 1 Screening serum metabolic markers for combined diagnosis of low bone density in laying hens

[0031] 1. Materials and reagents

[0032] Table 1 Instruments

[0033]

[0034] Table 2 Reagents

[0035]

[0036]

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Abstract

The invention discloses a method for screening serum metabolic markers of low bone density in laying hens, and a group of serum metabolic markers for combined diagnosis of low bone density screened from aged caged laying hens, the markers include Seven metabolites positively correlated with BMD and one metabolite negatively correlated with BMD. The present invention can jointly predict the risk of low bone density of caged laying hens by detecting these eight metabolic markers in the serum or plasma of laying hens, and then realize the effective prevention of osteoporosis in caged laying hens, and improve the economic efficiency in the laying hen breeding industry. It is of great significance in terms of economic efficiency and animal welfare.

Description

technical field [0001] The invention belongs to the field of biological detection and diagnosis, and in particular relates to a screening method for serum metabolic markers for combined diagnosis of low bone density of laying hens, and the invention also relates to a set of serum metabolic markers for joint diagnosis of low bone density of laying hens and its detection method. Background technique [0002] Osteoporosis in caged layer hens is a common bone metabolic disease in high-yielding caged layer flocks, characterized by increased bone fragility, decreased bone strength and bone density. Osteoporosis in caged laying hens has a greater impact on laying hens. On average, laying hens are artificially inseminated once every 5-6 days. Every time they grab the legs of breeders for artificial insemination, it is very easy to cause fractures in laying hens. Total loss of seed performance. In addition, when layer hens suffer from osteoporosis, they are not only prone to fractu...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N30/02G01N30/86
CPCG01N30/02G01N30/8675G01N30/8679G01N2030/047Y02T90/167Y04S30/12
Inventor 周忠新黄杰戴小方
Owner HUAZHONG AGRI UNIV