Absorbable anti-adhesion dressing and preparation method thereof

Abstract

The invention provides an absorbable anti-adhesion dressing. The absorbable anti-adhesion dressing sequentially comprises a hydrophobic layer, a hydrophilic layer and a protective layer from the sideclose to the skin, wherein the hydrophobic layer is a microsphere-loaded polycaprolactone/chitosan porous film; the hydrophilic layer is made of one or more selected from the group consisting of hyaluronic acid, gelatin, sodium alginate and keratin; and the protective layer is prepared by compounding an egg shell film and a modified polyurethane film. The invention also provides a preparation method for the absorbable anti-adhesion dressing. The absorbable anti-adhesion dressing prepared by using the preparation method provided by the invention can be degraded and absorbed, does not to be frequently replaced, maintains a moist environment beneficial to wound repair, has excellent mechanical properties and high antibacterial effect, can promote one-way absorption of a medicine, is improvedin utilization rate, does not generate the problem of wound adhesion when being replaced, and prevents secondary injury.

Description

technical field [0001] The invention belongs to the field of biological materials, in particular to an absorbable anti-adhesion dressing and a preparation method thereof. Background technique [0002] The skin is the largest organ of the human body and has the functions of retaining moisture in the body, preventing excessive heat dissipation, ventilating and preventing bacterial invasion. In daily life, wounds, abrasions, skin ulcers, burns and other wounds inevitably appear on the skin surface of the human body. If these wounds are not treated effectively, they may lead to a wider range of injuries, such as: infection, loss of body fluids, and various complications disease etc. [0003] If only a superficial layer or a small area of ​​the skin is damaged, the new skin will regenerate itself, but if it is severely traumatized, the skin cannot repair itself, and medical dressings are usually attached to promote wound healing. Traditional dressings such as absorbent cotton g...

AI Technical Summary

Problems solved by technology

Traditional dressings such as absorbent cotton gauze, cotton pads, and Vaseline gauze have a net-like weaving structure. Although they are cheap, the manufacturing process is relatively simple, the source of raw materials is wide, the texture is soft, and they have strong absorption capacity, they can prevent the accumulation of exudate on the wound surface. It also has a certain degree of protective effect on wound healing, but it cannot keep the wound mo...

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