Gamma-polyglutamic acid wound-protecting dressing

Abstract

The present invention relates to the technical fields of facial masks and a preparation method thereof, and particularly to a gamma-polyglutamic acid wound-protecting dressing. The gamma-polyglutamicacid wound-protecting dressing contains 0.05-0.1 wt% of gamma-polyglutamic acid. The gamma-polyglutamic acid is added into the facial mask dressing, can effectively increase moisturizing ability of the skin and promotes skin health; and in addition, a certain amount of the gamma-polyglutamic acid is added into the facial masks, can kill bacteria on the surface of the skin, promotes healing of skinwounds and plays a wet heating function during a facial mask applying process, and further promotes skin health.

Description

technical field

[0001] The invention relates to the technical field of facial masks and preparation thereof, in particular to a gamma-polyglutamic acid wound-protecting dressing. Background technique

[0002] γ-polyglutamic acid (γ-PGA) is a water-soluble, biodegradable, non-toxic polymer material. It is the main component of the viscous colloid of natto, a natural traditional fermented food. Homogeneous polypeptides polymerized by amide bonds can be produced on a large scale through microbial fermentation and can be naturally degraded. It is a safe and environmentally friendly biopolymer. γ-PGAγ-polyglutamic acid is a special anionic natural polymer, which is composed of amide linkage between α-amino and γ-caboxyl The molecular weight of the homopolyamide (homo-polyamide) γ-PGA ranges from 50,000 to 2 million Daltons. Since γ-PGA is the main component of natto viscous colloid, it has the effect of promoting mineral absorption. , Japan has included γ-PGA in its list of hea...

Examples

Embodiment 1

[0027] A gamma-polyglutamic acid wound dressing, comprising 0.06wt% of gamma-polyglutamic acid (relative average molecular weight range is 150-200kDa, its molecular weight distribution coefficient is 1.9-2.1), plant extract 3.24wt% (by Snow lotus extract, safflower extract, lily candidum extract, licorice extract are composed of 5:2:2:1 by weight), polypeptide 0.02wt% (composed of hexapeptide-9, palmitoyl pentapeptide-4, Palmitoyl tripeptide-1, palmitoyl tetrapeptide and sheep placenta peptide in a weight ratio of 5:2:1:1:2), methylparaben 0.32wt%, seaweed polysaccharide 0.05wt%, hydrolyzed collagen 15wt %, chitosan 0.12wt%, humectant 10wt% (composed of 1,3-propanediol, glycerin, butanediol and propylene glycol in a weight ratio of 10:5:1:2), monoglyceryl laurate 0.07wt%, Ascorbic acid 1.2wt%, the rest is water.

Embodiment 2

[0029]A gamma-polyglutamic acid wound dressing, comprising 0.06wt% of gamma-polyglutamic acid (relative average molecular weight range is 150-200kDa, its molecular weight distribution coefficient is 1.9-2.1), plant extract 2.5wt% (by Snow lotus extract, safflower extract, white lily flower extract, licorice extract are composed of 5:2:2:1 by weight), polypeptide 0.03wt% (composed of hexapeptide-9, palmitoyl pentapeptide-4, Palmitoyl tripeptide-1, palmitoyl tetrapeptide and sheep placenta peptide in a weight ratio of 5:2:1:1:2), methylparaben 0.25wt%, seaweed polysaccharide 0.06wt%, hydrolyzed collagen 12wt %, chitosan 0.1wt%, humectant 12wt% (composed of 1,3-propanediol, glycerin, butanediol and propylene glycol in a weight ratio of 10:5:1:2), monoglyceride laurate 0.06wt%, Ascorbic acid 0.8wt%, the rest is water.

Embodiment 3

[0031] A gamma-polyglutamic acid wound dressing, comprising 0.08wt% of gamma-polyglutamic acid (relative average molecular weight range is 150-200kDa, its molecular weight distribution coefficient is 1.9-2.1), plant extract 4.56wt% (by Snow lotus extract, safflower extract, candidum lily flower extract, and licorice extract are composed according to the weight ratio of 5:2:2:1), polypeptide 0.04wt% (composed of hexapeptide-9, palmitoyl pentapeptide-4, Palmitoyl tripeptide-1, palmitoyl tetrapeptide and sheep placenta peptide in a weight ratio of 5:2:1:1:2), methylparaben 0.45wt%, seaweed polysaccharide 0.08wt%, hydrolyzed collagen 12wt %, chitosan 0.15wt%, humectant 16wt% (composed of 1,3-propanediol, glycerol, butylene glycol and propylene glycol in a weight ratio of 10:5:1:2), monoglyceryl laurate 0.06wt%, Ascorbic acid 1.8wt%, the rest is water.

technical field

[0001] The invention relates to the technical field of facial masks and preparation thereof, in particular to a gamma-polyglutamic acid wound-protecting dressing. Background technique

[0002] γ-polyglutamic acid (γ-PGA) is a water-soluble, biodegradable, non-toxic polymer material. It is the main component of the viscous colloid of natto, a natural traditional fermented food. Homogeneous polypeptides polymerized by amide bonds can be produced on a large scale through microbial fermentation and can be naturally degraded. It is a safe and environmentally friendly biopolymer. γ-PGAγ-polyglutamic acid is a special anionic natural polymer, which is composed of amide linkage between α-amino and γ-caboxyl The molecular weight of the homopolyamide (homo-polyamide) γ-PGA ranges from 50,000 to 2 million Daltons. Since γ-PGA is the main component of natto viscous colloid, it has the effect of promoting mineral absorption. , Japan has included γ-PGA in its list of hea...

Examples

Embodiment 1

[0027] A gamma-polyglutamic acid wound dressing, comprising 0.06wt% of gamma-polyglutamic acid (relative average molecular weight range is 150-200kDa, its molecular weight distribution coefficient is 1.9-2.1), plant extract 3.24wt% (by Snow lotus extract, safflower extract, lily candidum extract, licorice extract are composed of 5:2:2:1 by weight), polypeptide 0.02wt% (composed of hexapeptide-9, palmitoyl pentapeptide-4, Palmitoyl tripeptide-1, palmitoyl tetrapeptide and sheep placenta peptide in a weight ratio of 5:2:1:1:2), methylparaben 0.32wt%, seaweed polysaccharide 0.05wt%, hydrolyzed collagen 15wt %, chitosan 0.12wt%, humectant 10wt% (composed of 1,3-propanediol, glycerin, butanediol and propylene glycol in a weight ratio of 10:5:1:2), monoglyceryl laurate 0.07wt%, Ascorbic acid 1.2wt%, the rest is water.

Embodiment 2

[0029]A gamma-polyglutamic acid wound dressing, comprising 0.06wt% of gamma-polyglutamic acid (relative average molecular weight range is 150-200kDa, its molecular weight distribution coefficient is 1.9-2.1), plant extract 2.5wt% (by Snow lotus extract, safflower extract, white lily flower extract, licorice extract are composed of 5:2:2:1 by weight), polypeptide 0.03wt% (composed of hexapeptide-9, palmitoyl pentapeptide-4, Palmitoyl tripeptide-1, palmitoyl tetrapeptide and sheep placenta peptide in a weight ratio of 5:2:1:1:2), methylparaben 0.25wt%, seaweed polysaccharide 0.06wt%, hydrolyzed collagen 12wt %, chitosan 0.1wt%, humectant 12wt% (composed of 1,3-propanediol, glycerin, butanediol and propylene glycol in a weight ratio of 10:5:1:2), monoglyceride laurate 0.06wt%, Ascorbic acid 0.8wt%, the rest is water.

Embodiment 3

[0031] A gamma-polyglutamic acid wound dressing, comprising 0.08wt% of gamma-polyglutamic acid (relative average molecular weight range is 150-200kDa, its molecular weight distribution coefficient is 1.9-2.1), plant extract 4.56wt% (by Snow lotus extract, safflower extract, candidum lily flower extract, and licorice extract are composed according to the weight ratio of 5:2:2:1), polypeptide 0.04wt% (composed of hexapeptide-9, palmitoyl pentapeptide-4, Palmitoyl tripeptide-1, palmitoyl tetrapeptide and sheep placenta peptide in a weight ratio of 5:2:1:1:2), methylparaben 0.45wt%, seaweed polysaccharide 0.08wt%, hydrolyzed collagen 12wt %, chitosan 0.15wt%, humectant 16wt% (composed of 1,3-propanediol, glycerol, butylene glycol and propylene glycol in a weight ratio of 10:5:1:2), monoglyceryl laurate 0.06wt%, Ascorbic acid 1.8wt%, the rest is water.

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