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Zhuang and Yao pharmaceutical preparation for treating diabetes

A technology for Zhuangyao medicine and diabetes, applied in the field of Zhuangyao medicine preparations, can solve problems such as severe side effects, liver and kidney dysfunction, etc., and achieve the effects of convenient taking, safe clinical use, and significant effects.

Inactive Publication Date: 2020-06-26
李德潮
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The drugs currently used clinically to treat diabetes are mostly insulin secretagogues (sulfonylureas, glinides), biguanides, thiazolidinedione insulin sensitizers, α-glucosidase inhibitors, diyl peptidase- Ⅳ (VDPP-Ⅳ) inhibitors, etc. These drugs have relatively large side effects, biguanides and α-glucosidase inhibitors cause severe gastrointestinal reactions, sulfonylureas cause severe liver and kidney dysfunction, thiazolidine two Ketone use also linked to increased risk of fractures and heart failure

Method used

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  • Zhuang and Yao pharmaceutical preparation for treating diabetes
  • Zhuang and Yao pharmaceutical preparation for treating diabetes

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0029] Get 750 Kg of poplar leaves, 150 Kg of guava leaves, and 300 Kg of konjac. Peel the dry product, cut into 0.5cm thick slices, add water to decoct twice, add water for the first time, decoct for 3 hours; 1000L, let it cool, add 1500L of 60% ethanol, stir evenly, keep it airtight for 24 hours, filter, recover ethanol from the filtrate, condense into a thick paste, use spray drying method to obtain the dried product of medicinal materials; crush the dry paste, add appropriate amount of konjac Fine powder, using gum arabic as a binder, granulating in a fluidized bed granulator, passing the granules through a 18-mesh sieve, filling the prepared granules into empty capsules, and filling the capsules to obtain capsules, packaging, and passing the inspection. That is the product (about 500,000 tablets).

example 2

[0030] Production Example 2: Get 750 Kg of leaves of Populus japonica, 150 Kg of guava leaves, and 300 Kg of konjac. Peel the dry product, cut into 0.5cm thick slices, add water to decoct twice, add water for the first time, decoct for 3 hours; 1000L, let cool, add 1500L of ethanol, stir evenly, airtightly stand for 24 hours, filter, the filtrate recovers ethanol, concentrates into a thick paste, and obtains the dried product of the medicinal material by spray drying method; the dry paste is crushed, and an appropriate amount of konjac fine powder is added, Use gum arabic as a binder, granulate in a fluidized bed granulator, pass the granules through a 18-mesh sieve, press the prepared granules into tablets, coat with film, pack, and pass the inspection to obtain the product (about 500,000 tablets ).

[0031] Typical cases:

[0032] 1. Li, male, 58 years old, went to the outpatient clinic for polydipsia, polyphagia, polyuria, weight loss, shortness of breath, and was diagnos...

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Abstract

The invention provides a Zhuang and Yao pharmaceutical preparation for treating diabetes. The Zhuang and Yao pharmaceutical preparation for treating diabetes comprises raw medicines in parts by weightof 1500 parts of adinandra nitida leaves, 300 parts of psidium guajava L and 600 parts of amorphophallus rivieri. The Zhuang and Yao pharmaceutical preparation is prepared through the steps of decocting the raw materials, performing concentration, performing ethanol precipitation with ethanol of 60%, performing drying by a spray drying method, performing crushing, performing granulation, adding an appropriate amount of amorphophallus rivieri fine powder, and preparing capsules or film coated tablets. According to a traditional traditional Chinese medicine and pharmacy theory and experience, the prepared Zhuang and Yao pharmaceutical preparation has the efficacy of supplementing qi, nourishing yin, clearing heat-fire and promoting the production of body fluid to quench thirst, is used fortreating type II diabetes, and is notable in effects, convenient to take, safe in clinical application, free from bad reactions and free from toxic and side effects.

Description

technical field [0001] The invention relates to a Zhuang Yao medicine preparation, in particular to a Zhuang Yao medicine preparation for treating diabetes. Background technique [0002] Diabetes mellitus is a metabolic disease characterized by hyperglycemia due to defects in insulin secretion or insulin action. Sustained high blood sugar and long-term metabolic disorders can lead to damage, dysfunction and failure of tissues and organs throughout the body, especially the eyes, kidneys, cardiovascular and nervous systems. Severe cases can cause acute complications such as dehydration, electrolyte disturbance and acid-base imbalance, ketoacidosis and hyperosmolar coma. Diabetes is a chronic disease that cannot be cured but can be controlled. It is characterized by high blood sugar, polyuria, polydipsia, polyphagia, and weight loss, that is, three more and one less. Diabetic complications are very dangerous. Eye disease, kidney disease and neurological disorders are the thre...

Claims

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Application Information

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IPC IPC(8): A61K36/888A61P3/10
CPCA61K36/61A61K36/82A61K36/888A61K2236/331A61K2236/51A61K2236/53A61P3/10A61K2300/00
Inventor 李德潮
Owner 李德潮
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