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Application of Amaronol A in control of infection of 2019-nCoV

A virus infection and amygdalin technology, which is applied in the field of medicine, can solve the problems of no efficient and specific protective equipment for blocking virus infection, lack of effective antiviral drugs for pathogens, etc.

Pending Publication Date: 2020-07-03
YUNNAN AGRICULTURAL UNIVERSITY +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is a lack of effective antiviral drugs against pathogens for the disease caused by the new coronavirus, and isolation treatment and symptomatic and supportive treatment are the main methods
At the same time, for the vast number of susceptible people, the current protective products such as masks and alcohol-containing disinfection products are all broad-spectrum protection, and there is no protective product on the market that is highly effective and specific for blocking virus infection

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0015] The disinfection gel after adding Amaronol A within the effective concentration range to the disinfection gel can effectively reduce the residue of the new coronavirus on the skin surface, thereby reducing the risk of infection.

example 2

[0017] Amaronol A within the effective concentration range is added to the interlayer of the mask to effectively isolate the new coronavirus from the outside of the mask from entering the respiratory system through breathing.

example 3

[0019] Compounds within the effective concentration range are added to the aerosol to effectively remove the infection of the new coronavirus in the respiratory system on the cells of the lungs and prevent respiratory infections.

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PUM

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Abstract

The invention relates to an efficient specific compound for controlling infection of 2019-nCoV and application of the efficient specific compound for controlling infection of the 2019-nCoV, and belongs to the technical field of medicines. Effective components of the compound comprise Amaronol A and Amaronol A derivatives (include but are not limited to analogues of Amaronol A methylates, modifiedAmaronol A and the like), and an effective use concentration range is between 10 ng / ml and 1000 [mu]g / ml or is between 10 ng / g and 1000 [mu]g / g. The compound is used for developing products, and the developed products are used for controlling infection of the 2019-nCoV, and can specifically weaken the invading capability of the 2019-nCoV, so that infection of the 2019-nCoV is controlled, and the human-to-human risk is reduced.

Description

technical field [0001] The invention belongs to the technical field of medicine, in particular, it relates to a class of high-efficiency and specific compounds for preventing and treating novel coronavirus infection and applications thereof. Background technique [0002] Novel coronavirus pneumonia, referred to as "new coronary pneumonia", is a type of acute infectious disease caused by 2019 novel coronavirus (2019-nCoV) infection. After a person is infected with the new coronavirus, the main symptoms include respiratory symptoms, fever, cough, shortness of breath, and dyspnea. In more severe cases, the infection can lead to pneumonia, severe acute respiratory syndrome, kidney failure, and even death. At present, there is a lack of effective antiviral drugs against pathogens for the disease caused by the new coronavirus, and isolation treatment and symptomatic and supportive treatment are the main methods. At the same time, for the vast number of susceptible people, the cur...

Claims

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Application Information

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IPC IPC(8): A61K31/343A61P31/14A61P11/00A61K8/49A61Q19/10
CPCA61K31/343A61P31/14A61P11/00A61K8/4973A61Q19/10
Inventor 盛军王宣军徐欢欢黄业伟朱强强吴晓云
Owner YUNNAN AGRICULTURAL UNIVERSITY