Preparation method of hypoglycemic oral liquid

An oral liquid and hypoglycemic technology, applied in the field of health-care oral liquid, can solve problems such as pain treatment, and achieve the effects of convenient drinking, suitable taste and reasonable ratio

Inactive Publication Date: 2020-08-18
盐城康林达生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, if diabetic patients take hypoglycemic drugs for a long time, the drug resistance of their islets will continue to increase, and patients will continue to increase the amount of drugs taken, which will eventually not only bring huge economic pressure to patients, but also cause pain in the treatment process, eventually leading to complications , such as foot gangrene, renal failure, heart disease, cerebrovascular disease, uremia and other diseases

Method used

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  • Preparation method of hypoglycemic oral liquid
  • Preparation method of hypoglycemic oral liquid
  • Preparation method of hypoglycemic oral liquid

Examples

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preparation example Construction

[0035] The preparation method of a preferred embodiment of the present invention for lowering blood sugar oral liquid includes the following steps:

[0036] Step 1: First weigh the raw materials according to the following parts by weight, 15g tartary buckwheat, 10g sea buckthorn, 7.2g kudzu root, 5g polygonatum, 5g cinnamon, 2.8g cabbage, and 2g mulberry leaves;

[0037] Step 2: Wash the tartary buckwheat, sea buckthorn, kudzu root, polygonatum, cinnamon, cabbage and mulberry leaves, and then dry them at a constant temperature at a constant temperature of 75℃-85℃ for a total of 3-5 Times

[0038] Step 3: Grind tartary buckwheat, sea buckthorn, kudzu root, polygonatum, cinnamon, cabbage and mulberry leaves respectively, with a particle size of 80 mesh to 100 mesh;

[0039] Step 4: Add 7 kinds of raw materials of tartary buckwheat, sea buckthorn, kudzu root, polygonatum, cinnamon, cabbage and mulberry leaves into 7 beakers containing 900 mL of deionized water, put them in an ultrasonic ...

Embodiment 1

[0052] The raw materials in this example are washed with water and placed in a drying box, dried at 75°C for 6 hours, dried at a constant temperature for 3 times, then mechanically crushed, passed through an 80-mesh sieve after crushing, ultrasonically extracted twice, and water extracted once at 90°C , Then transfer to an autoclave for 10 minutes at 100°C for sterilization. The oral liquid consists of 30 mL of Polygonatum water extract, 30 mL of cinnamon water extract, 15 mL of tartary buckwheat water extract, 1 mL of sea buckthorn water extract, and 1 mL of Chinese cabbage water extract. The mulberry leaf water extract 0.5mL and the kudzu root water extract 0.5mL are prepared. The filling is packed in a disposable brown bayonet bottle, each bottle is 10mL, and it is packed in a plastic oral liquid packaging box. The ratio of the oral liquid has a half inhibitory concentration IC50 for α-glucosidase of 1.322 mg / mL, and the taste is bitter.

Embodiment 2

[0054] The raw materials in this example are washed with water and placed in a drying oven, dried at 80°C for 7 hours, dried at a constant temperature for 4 times, then mechanically crushed, passed through a 90-mesh sieve after crushing, ultrasonically extracted 3 times, and 90°C water extracted once , Then transfer to an autoclave for sterilization at 115°C for 20 minutes. The oral liquid consists of Rhizoma Polygonatum water extract 40mL, Cinnamon water extract 40mL, Tartary buckwheat water extract 25mL, Seabuckthorn water extract 10mL, Chinese cabbage water extract 5mL, The mulberry leaf water extract 2mL and the kudzu root water extract 2mL are prepared. The filling is packaged in a disposable brown bayonet bottle, 10mL per bottle, and packed in a plastic oral liquid packaging box for external use. The oral liquid with this ratio has a half-inhibitory concentration IC50 for α-glucosidase of 0.947 mg / mL, and the taste is bitter.

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Abstract

The invention relates to a hypoglycemic oral liquid, which is prepared from the following raw materials (by weight): 34.52%-43.87% of tartary buckwheat, 1.84%-11.02% of sea-buckthorn, 0.05%-2.21% of radix puerariae, 20.47%-27.65% of rhizoma polygonati, 20.64%-27.65% of cortex cinnamomi, 0.52%-2.15% of gynura divaricata, 0.15%-0.61% of folium mori and the balance deionized water. The health tea belongs to a medicinal and edible product, is reasonable in proportion, proper in taste and convenient to take, can reduce blood sugar on the basis of not injuring liver and kidney organs of diabetic patients, and is suitable for people with hyperglycemia and diabetic patients; and the hypoglycemic oral liquid can effectively improve pathological changes of liver tissues, inhibit activity of alpha-glucosidase in a body, reduce generation of glucose and reduce blood sugar concentration, and achieves the effect of repairing liver injury by improving the free radical scavenging capacity of the body.

Description

Technical field [0001] The invention relates to the field of a health-care oral liquid, in particular to a preparation method of a hypoglycemic oral liquid. Background technique [0002] As we all know, diabetes is a metabolic disease characterized by high blood sugar due to insufficient insulin secretion capacity of patients and the gradual decrease of the body's sensitivity to insulin. In the past few decades, the process of urbanization in China has developed rapidly, and the development of urbanization is related to changes in residents’ lifestyles. Environmental factors such as lack of exercise, unhealthy diet, and obesity are all related to the pathogenesis of diabetes. Lead to a significant increase in the number of diabetes in my country. [0003] At present, there is no cure for diabetes at home and abroad, and it can only rely on taking hypoglycemic drugs or insulin injections to temporarily control and stabilize blood sugar levels. However, if diabetic patients take hyp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K36/8969A61P3/10
CPCA61K9/0095A61K36/185A61K36/28A61K36/488A61K36/54A61K36/605A61K36/70A61K36/8969A61P3/10A61K2300/00
Inventor 程德林葛小东黄从军黄丽杰
Owner 盐城康林达生物科技有限公司
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