66 results about "Glucosidase activity" patented technology

The invention discloses a thiochromanone derivative containing a thiosemicarbazone structure and application of the thiochromanone derivative, relates to the technical field of medicines, and particularly relates to the technical field that the compound has better oxidation resistance and alpha-glucosidase resistance activity, the IC50 value of the compound 1-(7-chloro-4, 4-dioxothiochromanone-3-N-propyl) thiosemicarbazone to ABTS clearance activity is 2.86 [mu] g / mL, the IC50 value of the compound 1-(7-chloro-4, 4-dioxothiochromanone-3-N-propyl) thiosemicarbazone to alpha-glucosidase inhibition activity is 9.51 [mu] g / mL, and the effect is the best and is superior to that of a control agent vitamin E and acarbose. The thiochromanone derivative containing the thiosemicarbazone structure has a general formula shown in the specification,

In the present application, by knocking out the BG gene in Trichoderma reesei PX3 (a strain of cellulase transcription activator that can be activated continuously), the BG activity can be reduced under the condition of not reducing or even increasing the filter paper enzyme activity of the enzyme system, and a low BG enzyme activity and high filter paper enzyme activity strain is constructed. This strategy can avoid the negative impact on cellulase production after BG knockout, and the obtained strain can be used for efficient production of cellobiose or as a chassis strain for producing cellulase.

This invention belongs to the field of carbon nanomaterials technology, specifically disclosing a method for preparing and applying carbon dots from *Pu Di Lan* (a type of medicinal herb) residue. The specific steps are as follows: dried *Pu Di Lan* residue is pulverized using a cell wall breaker to obtain *Pu Di Lan* residue powder; the powder is then reacted using a hydrothermal method; the reaction solution is collected; the reaction solution is centrifuged, and the supernatant is collected; the supernatant is filtered, and the filtrate is collected; the filtrate is dialyzed, and the retaining liquid is collected; the retaining liquid is freeze-dried to obtain the *Pu Di Lan* residue carbon dots. The obtained *Pu Di Lan* residue carbon dots exhibit blue fluorescence under a 365 nm ultraviolet lamp, and their surface is rich in functional groups such as hydroxyl and carboxyl groups, showing good hydrophilicity. The *Pu Di Lan* residue carbon dots promote β-D-glucosidase activity and can be used in food processing; simultaneously, the fluorescence of the *Pu Di Lan* residue carbon dots is highly sensitive to β-D-glucosidase, and β-D-glucosidase activity can be detected by fitting a linear regression equation with a standard solution.

This invention relates to the field of soil treatment technology, specifically a method and its application for reducing compound fungicides in soil-plant systems by combining nano-silica and nitrification inhibitors. Nitrification inhibitors are used as a nitrogen management measure, and the application of nanomaterials influences soil abiotic properties and bacterial communities to drive the degradation of paclobutrazol and carbendazim. The application of nitrification inhibitors (DCD) produces multiple effects: significantly reducing carbendazim residues in soil-plant systems, paclobutrazol residues in soil, and NO3 in plants. ‑ -N and promote the content of soluble sugars and proline in plants. DCD reduces the activity of the soil electron transport system and β-glucosidase activity, while the addition of nano-SiO2 can mitigate this negative effect. Nano-SiO2 selectively enhances the performance of DCD in reducing compound fungicide residues in pak choi and reducing paclobutrazol residues, but hinders the degradation of carbendazim in pak choi.

The invention belongs to the field of food science and engineering, and discloses a preparation method of an active medicinal and edible composite nutrient AMCN with an anti-aging effect, and the preparation method comprises the following steps: putting a ganoderma lucidum monoclonal strain into a liquid culture medium for controllable culture to obtain supernate with beta-glucosidase activity of over 100mU / mL; and adding rhizoma polygonati powder, lucid ganoderma powder and mulberry leaf powder, carrying out enzymatic biotransformation, carrying out lactobacillus plantarum fermentation, adding a freeze-drying protective additive, carrying out freeze-drying, grinding to obtain the active medicinal and edible composite nutrient AMCN, and storing the finished product in a dry and dark place. The active medicinal and edible composite nutrient can be used for preparing anti-aging functional foods or nutritional health-care products. A D-galactose induced zebrafish aging model verifies that the active medicinal and edible composite nutrient prepared by the application plays an anti-aging role by relieving oxidative stress, inhibiting cell aging and maintaining telomere stability, can reduce beta-galactosidase activity and intracellular ROS (reactive oxygen species) level, improves telomerase protein concentration, and has a good anti-aging effect. And the telomere length can be effectively recovered by medium and high concentrations.

The invention discloses a pyrimidine derivative containing a thiosemicarbazide structure and application of the pyrimidine derivative, and relates to the technical field of medicines, the compound has good oxidation resistance and alpha-glucosidase resistance activity, and the compound is 2-(4, 4 '-difluorophenyl)-2-(4, 4'-difluorophenyl)-2-(4, 4 '-difluorophenyl)-2-(4, 4' The IC50 values of the compound 2-(4, 6-dimethyl pyrimidine-2-yl)-N-methylhydrazine-1-methylsulfamide on DPPH (1, 1-diphenyl-2-picrylhydrazyl) scavenging activity and ABTS (2, 2, 6-dimethyl pyrimidine-2-yl)-N-methylhydrazine-1-methylsulfamide are 3.96 mu g / mL and 2.01 mu g / mL respectively, the IC50 value of the compound 2-(4, 6-dimethyl pyrimidine-2-yl)-N-methylhydrazine-1-methylsulfamide on alpha-glucosidase inhibitory activity is 38.62 mu g / mL, the effect is best, and the compound 2-(4, 6-dimethyl pyrimidine-2-yl)-N-methylhydrazine-1 The pyrimidine derivative containing the thiosemicarbazide structure has a general formula shown in the specification, and is superior to control medicaments such as vitamin C, vitamin E and acarbose.

This invention discloses a low glycemic index (GI) Hericium erinaceus (monkey head mushroom) steamed bun, belonging to the field of food processing and functional food applications. By weight, it is prepared from the following raw materials: 45-55 parts all-purpose flour, 28-35 parts Hericium erinaceus extract powder, 0.3-0.35 parts yeast, 15-18 parts water, 0.3-0.6 parts oil, and 0.7-0.9 parts sugar. This invention partially replaces the flour with Hericium erinaceus extract powder, fully utilizing the multiple mechanisms of action of Hericium erinaceus polysaccharides in forming a viscous gel in the digestive tract to slow down the contact between amylase and substrate, inhibiting α-amylase and α-glucosidase activity, and improving intestinal microecology and enhancing insulin sensitivity through dietary fiber. This allows the product to meet the low-GI food standard (GI<55), effectively filling the gap in low-GI steamed buns with Hericium erinaceus functional components as the core active ingredient. It has significant application value in the fields of diabetes management, weight control, and healthy staple foods.

The application discloses a kind of complex fermentation inoculant for improving equol production, fermentation liquor and application thereof, belong to microbial fermentation technical field.The complex fermentation inoculant of the application, streptococcus thermophilus BLCC2-0025 and lactococcus lactis MP1001 have high β-glucosidase activity, and low activity glycoside form is converted into high activity daidzein;Salivary lactobacillus LS1101 and lactobacillus gregius 0010 have the activity of further converting daidzein into equol;Four strains of bacteria are used in combination, which can synergistically improve the content of equol.The fermentation liquor prepared by fermenting pueraria extract with the complex fermentation inoculant of the application can target regulate intestine-ovary axis, significantly improve the reproductive function of POF mice, relieve ovarian oxidative stress and accurately regulate intestinal flora balance, providing a safe and effective preparation and application scheme for non-hormone intervention of premature ovarian failure.

The application provides a compound shown in formula I or a pharmaceutically acceptable salt thereof: wherein R4 is selected from a hydroxyl group, an O-beta-D Glc group, and an O-beta-D Glc-(2-1)-alpha-L-Rha group; and R8 is selected from a hydroxyl group, an O-beta-D Glc group, and an O-beta-D Glc-(2-1)-alpha-L-Rha group; and the application provides the use of the compound in the preparation of a blood sugar reducing drug and in the inhibition of alpha-glucosidase activity, and has the beneficial effect that the application provides the use of zeylasteroside D and zeylasteroside J in the preparation of a blood sugar reducing drug and in the inhibition of alpha-glucosidase activity, and discloses the compound structure of zeylasteroside L and the use of the zeylasteroside L in the preparation of a blood sugar reducing drug and in the inhibition of alpha-glucosidase activity.

The invention discloses preparation and application of a corn polypeptide with functions of inhibiting amyloglucosidase activity and promoting GLP-1 secretion, and belongs to the technical field of functional food. And the corn polypeptide is PYPR, PPAPR and PLRP (Poly Lactic Polymerase Chain Reaction). The corn polypeptide is obtained by enzymolysis of corn protein through alkaline protease, and is novel in structure and easy to prepare. The corn polypeptide can inhibit the activity of amyloglucosidase in vitro, can significantly promote GLP-1 secretion, and can up-regulate the expression of gcg and gc3 genes related to GLP-1 synthesis and a polypeptide recognition receptor GPR93 by regulating Ca < 2 + > influx and an ATP signal channel, thereby improving the steady state of blood glucose. The invention provides reference for developing functional food or health care products with the functions of reducing blood sugar and promoting secretion of insulin.

The present application relates to the field of biotechnology, and more particularly to a cassava peptide for inhibiting alpha-glucosidase activity and a preparation method thereof. The present application recovers cassava starch wastewater protein by acid precipitation method, and obtains high-activity alpha-glucosidase inhibitory peptides by heat and ultrasonic pretreatment of cassava protein to assist enzymatic hydrolysis. The peptide sequence is analyzed, the alpha-glucosidase inhibition type is determined, four cassava peptides with alpha-glucosidase activity are obtained, and their high alpha-glucosidase inhibitory activity in vivo and in vitro is verified. A new alpha-glucosidase inhibitory peptide is given, the blank in the prior art is overcome, and a new idea for high-value utilization of cassava processing wastewater is provided.

This invention provides a type of yeast called *Saccharomyces clavatum*, characterized in that the *Saccharomyces clavatum* is: *Saccharomyces clavatum* (… Saccharomycopsis fibuligera AMCC 32248, preservation number CCTCC NO: M 20251908. Enzyme activity phenotypic screening, carbon source utilization analysis, and quantitative enzyme activity detection showed that this strain possesses highly efficient β-glucosidase activity; further analysis of key genes related to β-glucosidase... BGL1 Specific functional sequences were extracted and identified. Enzyme production conditions were optimized using response surface methodology, resulting in a significant increase in enzyme activity compared to before optimization. In a simulated fermentation system, this strain significantly promoted the production of specific acids, esters, aldehydes, alcohols, and other volatile flavor compounds. Its enzyme production characteristics and flavor regulation capabilities provide a new technical solution for addressing issues such as low hydrolysis efficiency of glycosides and insufficient flavor release in fermentation systems, showing potential applications in the food, brewing, feed, and pharmaceutical industries.

The application discloses application of a hypoglycemic peptide in preparation of a medicine for inhibiting alpha-amylase and alpha-glucosidase activity. The hypoglycemic peptide is derived from Hericium erinaceus, and the amino acid sequence is AVFPSIVGRPR. The polypeptide is extracted and purified from Hericium erinaceus fruiting body protein, the amino acid sequence of one hypoglycemic peptide is determined by LC-MS / MS, the alpha-amylase inhibition rate is 71.86%±0.08% through hypoglycemic activity detection, and the alpha-glucosidase inhibition rate is 61.52%±0.15%, so the hypoglycemic peptide can be used as a natural hypoglycemic peptide and has a potential application prospect in the field of preparation of medicines for reducing blood sugar and the like.

The invention provides a Trichoderma reesei engineering bacterium for high yield of beta-glucosidase, which is characterized in that a Trichoderma reesei SN1 strain is used as a starting strain, and an expression cassette for knocking out a cre1 gene, a constitutive expression cassette of an aspergillus niger source bglA gene expressed by a promoter cbh1 and a constitutive expression cassette of a 130442 gene expressed by the promoter cbh1 are constructed in a genome of the Trichoderma reesei SN1 strain. Through the knockout of the cre1 gene, the overexpression of the aspergillus niger source bglA gene and the overexpression of the 130442 gene, the yield of the beta-glucosidase in the trichoderma reesei is improved synergistically. Glucose is taken as a raw material, a transglycosylation reaction can be catalyzed by directly utilizing a crude enzyme solution of trichoderma reesei engineering bacteria with high yield of beta-glucosidase to prepare beta-disaccharide, and the beta-disaccharide can be taken as an inducer for cellulase production; a crude enzyme liquid with higher cellulase activity and beta-glucosidase activity is obtained by supplementing an inducer and carrying out fed-batch fermentation.

The invention belongs to the technical field of tobacco strains, and particularly relates to a rhodotorula mucilaginosa H04 strain and application thereof in preparation of tobacco flavor. The rhodotorula mucilaginosa H04 provided by the invention has excellent aroma producing performance and can produce tobacco characteristic aroma substances such as alcohols, aldehydes, esters and pyrazines at high yield. The rhodotorula mucilaginosa H04 has good tolerance to nicotine, can still keep high growth activity under the condition that the nicotine concentration is as high as 8 mg / mL, and is suitable for being used for preparing tobacco flavor; the tobacco flavor prepared by the invention contains a plurality of natural aroma components, has good coordination with the original aroma of tobacco, and can significantly improve the aroma richness and comfort of tobacco products; the highest beta-glucosidase activity of the rhodotorula mucilaginosa H04 reaches 464.0 + / -24.4 U / mL, and the laccase activity reaches 60.4 + / -3.2 U / mL, so that the release of bound aroma precursor substances in tobacco is facilitated, and the aroma expression is enhanced.

The invention discloses a hesperetin derivative containing a thiosemicarbazone structure and application of the hesperetin derivative, the molecular formula of the compound is C18H19N3O5S, the biological activity determination result shows that the compound has good anti-oxidation and anti-alpha-glucosidase activity, the IC50 value of DPPH scavenging activity is 6.17 mu g / mL, and the activity of the hesperetin derivative is equivalent to that of a control agent vitamin C. The hesperetin derivative containing the thiosemicarbazone structure and the application of the hesperetin derivative containing the thiosemicarbazone structure have good anti-oxidation and anti-alpha-glucosidase activity. The IC50 value of ABTS clearance activity is 0.04 mu g / mL, and the activity is improved by 200 times compared with that of a control medicament vitamin E; the IC50 value of the alpha-glucosidase inhibitory activity is 4.53 [mu] g / mL, which is improved by 51 times compared with the activity of a control agent acarbose; the structural formula of the hesperetin derivative containing the thiosemicarbazone structure is shown in the specification.

The invention belongs to the technical field of microorganisms, and particularly relates to bacillus velezensis, a straw degradation agent, a preparation method, a straw degradation method and application. The invention provides a bacillus velezensis LLS, and the preservation number of the bacillus velezensis LLS is CGMCC (China General Microbiological Culture Collection Center) No.35634. The bacillus velezensis LLS provided by the invention is high in cellulase total activity, endo beta-1, 4-glucosidase activity, exo beta-1, 4-glucosidase activity, beta-1. 4-glucosidase activity, lignin peroxidase activity, laccase activity and manganese peroxidase activity, can tolerate low temperature, and can be used for preparing the bacillus velezensis LLS. The straw degradation effect is good under the low-temperature condition.

The invention provides saccharomycopsis fibuligera, which is characterized in that the saccharomycopsis fibuligera is saccharomycopsis fibuligera AMCC 32248, and the preservation number of the saccharomycopsis fibuligera is CCTCC (China Center for Type Culture Collection) NO: M 20251908. Enzyme activity phenotype screening, carbon source utilization analysis and enzyme activity quantitative detection show that the strain has efficient beta-glucosidase activity; furthermore, the key gene BGL1 of the beta-glucosidase is called, and a specific functional sequence is excavated. The enzyme production condition is optimized through a response surface method, and the enzyme activity is remarkably improved compared with that before optimization. In a simulated fermentation system, the strain can remarkably promote generation of volatile flavor substances such as specific acids, esters, aldehydes and alcohols, and a new technical scheme is provided for solving the problems of low hydrolysis efficiency of glycoside substances, insufficient flavor release and the like in the fermentation system due to the enzyme production characteristic and flavor regulation and control capability of the strain. The method has application potential in the fields of food, brewing, feed, medicine and the like.

This invention belongs to the field of biomedical technology, specifically disclosing a blood sugar-lowering probiotic and its application. The strain is Staphylococcus xylose (S. xylose). Staphylococcus xylosus. BC100, deposited on December 12, 2025, at the China General Microbiological Culture Collection Center (CGMCC) with accession number CGMCC No. 37053, located at Institute of Microbiology, Chinese Academy of Sciences, No. 3, Courtyard 1, Beichen West Road, Chaoyang District, Beijing. Compared with existing technologies, the fermentation broth of *Staphylococcus xylose* strain BC100 provided by this invention has the effect of inhibiting α-amylase and α-glucosidase activities. Furthermore, the fermentation broth of this strain combined with fruit enzymes exhibits even better inhibitory effects, particularly when combined with lemon enzymes and apple enzymes. This strain can be used to develop oral or other products for lowering blood sugar and has significant application value.

The invention belongs to the technical field of biological medicine, and relates to sargassum polysaccharide as well as a preparation method and application thereof. The uniform acidic polysaccharide WZSP-2 is separated and purified from the Weizhou Sargassum through hot water extraction, ethanol precipitation, protein and color removal, anion exchange column and gel column chromatography and other methods, and the physicochemical properties, monosaccharide composition and structural morphology of the Weizhou Sargassum are systematically characterized. In-vitro experiments show that the WZSP-2 has remarkable DPPH, ABTS and hydroxyl radical scavenging capacity and total reducing power, can effectively inhibit the activity of alpha-amylase and alpha-glucosidase, can be combined with glycocholate and taurocholate, and has a bacteriostatic effect on methicillin-resistant staphylococcus aureus (MRSA) at the same time. The sargassum polysaccharide provided by the invention integrates antioxidant activity, hypoglycemic activity, hypolipidemic activity and antibacterial activity, provides a new source for developing multifunctional natural products, and has a good application prospect in the fields of functional food, health care products and medical auxiliary materials.

The invention relates to the technical field of biology, in particular to a zymomonas mobilis recombinant strain for producing ethanol by taking cellobiose as a raw material and application of the zymomonas mobilis recombinant strain. On the basis of recombinant zymomonas mobilis expressing beta-glucosidase, an efficient cellobiose conversion system is constructed through the synergistic effect of promoter and signal peptide optimization and gene multi-copy regulation, the activity of extracellular beta-glucosidase is remarkably improved, cellobiose is accelerated to be hydrolyzed into glucose, and the activity of beta-glucosidase is improved. The yield of ethanol is promoted to be obviously improved. Based on the fact that no linear positive correlation exists between the activity of beta-glucosidase and the yield of ethanol, the bottleneck of cellulose degradation under high substrate concentration is solved through multi-element coordinated regulation and dynamic matching of enzyme activity and substrate metabolism, and the energy efficiency and industrial application value of biomass energy conversion are remarkably improved.

The invention discloses a high-yield beta-glucosidase strain and application of the high-yield beta-glucosidase strain in efficient conversion of genistin, and belongs to the technical field of microbial fermentation and enzyme engineering. In order to solve the problems of low enzyme activity and low conversion efficiency of a beta-glucosidase production strain in the prior art, the invention provides the lactobacillus mucus DQ7-1 of which the preservation number is CGMCC (China General Microbiological Culture Collection Center) No.36230, and the lactobacillus mucus DQ7-1 has the advantages that the lactobacillus mucus DQ7-1 has the preservation number of CGMCC No.36230; the strain is obtained through natural fermentation with soybean whey as a raw material in combination with aesculin color development and p-nitrobenzene-beta-D-glucopyranoside quantitative enzyme activity screening methods, and the beta-glucosaccharase activity of the strain is remarkably higher than that of common lactic acid bacteria. The strain is mainly used for catalyzing efficient conversion of soybean isoflavone glycoside, especially genistin, to genistein in the aglycone form, and has important application value in the fields of functional food, medicine and feed.

The invention relates to the field of microorganisms, in particular to a plant lactobacillus and application thereof. The invention provides lactobacillus plantarum, and the preservation number of the lactobacillus plantarum is GDMCC 66229. The lactobacillus plantarum has the advantages that the preservation number is CGMCC 66229, and the preservation number is CGMCC 66229; the lactobacillus plantarum SCUT732 provided by the invention has excellent acid resistance and bile salt resistance, has good beta-glucosidase activity, and has excellent capability of degrading uric acid precursor inosine and guanosine.

This invention belongs to the field of biotechnology, specifically relating to an α-glucosidase inhibitory peptide and its applications. The invention uses oat bran as raw material to extract protein, prepares oat bioactive peptides through enzymatic hydrolysis, and uses bioinformatics analysis to screen for the α-glucosidase inhibitory peptide RELGGFF, which exhibits an IC50 value of 531.90±5.23 μg / mL against α-glucosidase. Furthermore, the inhibitory effect of the combined use of the α-glucosidase inhibitory peptide RELGGFF and oat β-glucan on α-glucosidase activity is investigated, and its application can be explored in the preparation of products that inhibit α-glucosidase activity, in the preparation of hypoglycemic products, or in the preparation of products for treating diabetes.

This invention discloses a strain of Aspergillus oryzae AspG1 and its application in Pu-erh tea fermentation, belonging to the field of microbial strain resource development and deep processing technology of tea. The method provided by this invention includes: mixing sun-dried Pu-erh tea raw materials with water at a 1:1 ratio, sterilizing to obtain a solid tea base, inoculating with AspG1 strain, and then carrying out solid-state fermentation under staged temperature control conditions. Experiments showed that the fermentation product exhibited sweet and fruity aroma characteristics on day 14, and purified to floral aroma on day 21; the protease activity of AspG1 strain was increased by 229.42% compared with the control, and the β-glucosidase activity was increased by 58.21%; gas chromatography-mass spectrometry analysis showed that the cis-linalool OAV value in the AspG1 fermentation product reached 275.41 (approximately 31.8 times higher than the control), and 1-octen-3-one was specifically detected (OAV reached 228967.43). This invention provides microbial resources and process solutions for the targeted regulation of aroma in the solid-state fermentation of Pu-erh tea.

This invention discloses the application of tauroursodeoxycholic acid (TUDCA) in inhibiting α-glucosidase activity, belonging to the field of biotechnology. The invention utilizes porcine bile salts and bear bile powder for in vitro α-glucosidase inhibition experiments, performs molecular docking simulations on the components, and screens multiple bile acids for α-glucosidase inhibition, ultimately identifying TUDCA as the experimental material. Furthermore, in vivo and in vitro experiments were conducted to study the effects of TUDCA on α-glucosidase, revealing that TUDCA can significantly inhibit α-glucosidase activity and alleviate insulin resistance, classifying it as an anti-competitive inhibitor. This invention provides a novel raw material for inhibiting α-glucosidase activity, which can be applied to α-glucosidase activity inhibitors or drugs for alleviating insulin resistance.

The invention relates to the technical field of plant extraction, and discloses a loquat peel alcohol extract as well as a preparation method and application thereof. In the loquat peel alcohol extract, the total flavonoid content is greater than or equal to 6.3 wt%, the polyphenol content is greater than or equal to 3.3 wt%, and the total content of 24 common phenols is greater than or equal to 2.5 mg / g. The loquat peel alcohol extract with high biological activity is obtained through process optimization, and particularly, it is found that the loquat peel alcohol extract has a more remarkable inhibition effect on alpha-glucosidase activity for the first time; furthermore, ingredients in the loquat peel alcohol extract are identified through LC-MS, and specific active ingredients capable of inhibiting the activity of alpha-glucosidase in the loquat peel alcohol extract are clarified through molecular docking.

The invention designs a preparation method of an active medicinal and edible composite nutrient, and the method comprises the following steps: carrying out initial culture on a ganoderma lucidum monoclonal isolate through a potato dextrose agar plate, and then transferring the ganoderma lucidum monoclonal isolate to a specific liquid culture medium for shake culture; after detecting that the activity of beta-glucosidase reaches 100 mU / mL, centrifuging to take supernatant, and adding rhizoma polygonati, lucid ganoderma and mulberry leaf powder for biotransformation; and inoculating lactobacillus plantarum, adding a freeze-drying protective additive, freeze-drying, and sieving to obtain the active medicinal and edible composite nutrient. According to the method, macromolecular active components of lucid ganoderma, rhizoma polygonati and folium mori are decomposed into small molecules through biotransformation, the problem that a traditional material is poor in intestinal absorption is solved, the prepared active medicinal and edible composite nutrient can restore the number of neutrophils, macrophages and T cells, meanwhile, tnf-alpha, il-12a and ifn-gamma proinflammatory gene expression is up-regulated, and the effect of improving the intestinal absorption rate is achieved. In addition, the natural source is high in safety, and can be used for an immune function regulation scene.

The invention relates to the technical field of microorganisms, and discloses a plant lactobacillus IMAUJBP6 strain and application thereof. The plant lactobacillus IMAUJBP6 is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation number is CGMCC No.36779, and the preservation date is November 26, 2025. The plant lactobacillus IMAUJBP6 obtained by screening can play an anti-oxidation role by inhibiting the activity of alpha-amylase and alpha-glucosidase and improving the DPPH free radical scavenging rate, the superoxide anion free radical scavenging rate and the hydroxyl free radical scavenging rate at the same time, so that the effect of reducing blood sugar is synergistically achieved. When the strain is applied to preparation of fermented milk, a fermented milk product with excellent quality can be obtained, especially when camel milk is used as a raw material for fermentation, the product shows a remarkable potential probiotic effect in the aspects of reducing blood sugar and resisting oxidation, and a new strain and a technical support are provided for development of functional fermented milk products and products for reducing blood sugar and resisting oxidation.

The invention provides a plant lactobacillus capable of producing lactic acid and beta-glucosidase at high yield and application thereof, and belongs to the technical field of microbial fermentation. According to the lactobacillus plantarum HW-3, the lactobacillus plantarum HW-3 is screened from grape mash in the middle and later periods of natural fermentation in the Hexi Corridor production area in Gansu Province, the lactobacillus plantarum HW-3 is better than a commercial strain WCFS1 in lactic acid production capacity, meanwhile, the lactobacillus plantarum HW-3 has high beta-glucosidase activity, when the lactobacillus plantarum HW-3 is inoculated into grape juice for fermentation, the good flower and fruit aroma capacity of a fermented product can be improved, and the yield of the fermented product is increased. The sensory evaluation acceptability is higher; the strain not only can better adapt to the characteristics of raw materials and improve the fermentation efficiency and flavor expression, but also can show the flavor potential of special fruits and vegetables in China, endows products with regional characteristics and unique styles, and has important strategic significance for promoting the high-quality and special development of the fermented fruit and vegetable beverage industry in China.