55 results about "High amylose" patented technology

The invention discloses a molecular marker remarkably related to the amylose content of wheat and application of the molecular marker, and belongs to the technical field of wheat breeding. Three mutation sites of wheat starch branching enzyme gene SBEIIa on 2A, 2B and 2D chromosomes and two mutation sites of SBEIIb on 2A and 2B chromosomes are identified, a KASP molecular marker system closely linked with SBEIIa and / or SBEIIb is developed based on the SNP sites, the detection process is simple and convenient, the cost is low, the throughput is high, and the application prospect is wide. According to the method, the high-amylose wheat material which contains the mutant genotype and can be stably inherited can be accurately and efficiently screened out, the breeding process of wheat variety quality improvement can be accelerated, and the method has important significance on creation of the high-amylose wheat material or molecular assisted breeding of the high-amylose wheat.

The invention discloses a formaldehyde-free composite board for a cabinet and a preparation method of the formaldehyde-free composite board, and relates to the technical field of artificial board manufacturing. The preparation method of the formaldehyde-free composite board for the cabinet comprises the following steps: mixing high amylose with a choline chloride / urea deep eutectic solution, stirring, adding concentrated hydrochloric acid for reaction, adjusting the pH value, and adding ammonium persulfate to obtain pretreated oxidized starch; methacrylic acid dehydrated glyceride is added into the pretreated oxidized starch for a grafting reaction, then modified polyvinyl alcohol is added for blending, sodium metaphosphate is added for crosslinking, finally, heating and curing are conducted, modified titanium dioxide nanoparticles are added, and the formaldehyde-free starch adhesive is obtained. The wood shavings and the formaldehyde-free starch adhesive are mixed, and a core material is obtained; and arranging the core material between the formaldehyde-free veneers, and carrying out hot press molding to obtain the formaldehyde-free composite board. The formaldehyde-free composite board for the cabinet has excellent mechanical strength, bonding performance and water resistance.

The invention belongs to the technical field of wood adhesives, and particularly relates to preparation of a starch-based full-biomass green adhesive with high adhesive strength and hot water soaking resistance and application of the starch-based full-biomass green adhesive in wood processing. The method comprises the following steps: preparing a starch-based adhesive from high amylose and tannic acid, treating the surface of wood by using KH560, coating a wood board with the starch-based adhesive, pressing and drying to obtain the plywood. Even if the plywood is soaked in water of 30 DEG C or hot water of 60 DEG C for 3 hours, the plywood does not have glue failure, the shearing strength is higher than 1.0 MPa when the plywood is torn, and the use requirements of national standard II-type plywood are met.

The invention belongs to the technical field of perfumed soap preparation, and relates to a preparation method of pea starch-based transparent perfumed soap, which comprises the following steps: firstly, taking 19-20 parts by weight of pea starch and 80-90 parts by weight of water to prepare transparent starch milk; cooling the starch milk to 70-80 DEG C, adding 10-15 parts of coconut oil, 15-20 parts of beef tallow and 10-20 parts of sodium hydroxide, and stirring at constant temperature for 4-6 hours to finish emulsification; then adding glycerol, 5-10 parts of rock candy and 4-6 parts of propolis, uniformly mixing, injecting into a mold, freezing and molding, and demolding; and finally, cooling the soap block in a ventilated environment with the temperature of 25 DEG C and the humidity of 40%, controlling the water loss rate to be about 1.15% / day, and drying until the total water loss rate is about 12% to obtain a finished product. According to the invention, a stable starch oil gel system is constructed by utilizing the characteristic of high amylose content of pea starch, so that the problems of insufficient transparency, poor elasticity and poor stability of the existing starch-based transparent soap are solved.

A novel hybrid corn plant, designated A8367 is disclosed. The technology relates to the seeds of hybrid corn A8367, to the plants and plant parts of hybrid corn A8367, and to methods for producing a corn plant by crossing the hybrid corn A8367 with itself or another corn plant. The technology further relates to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other hybrid corn plants derived from the hybrid corn plant A8367. Starch from corn seed obtained from A8367 is high amylose corn starch having high total dietary fiber content.

The present invention discloses a double-network gel microsphere with pH response and its preparation method and application. The preparation method comprises: reacting indolepropionic acid with 2-hydroxyethyl vinyl ether under the catalytic action of EDC and NHS to prepare indolepropionic acid-2-hydroxyethyl vinyl ether polymer; reacting the indolepropionic acid-2-hydroxyethyl vinyl ether polymer with high-amylose starch under the catalytic action of p-toluenesulfonamide to prepare indolepropionic acid grafted starch; and mixing the indolepropionic acid grafted starch, sodium alginate and water as a dispersed phase; making a solution containing at least a surfactant as a continuous phase, and then using microfluidic technology to prepare double-network gel microspheres with pH response. The double-network gel microspheres with pH response prepared by the present invention have good thermal stability and pH responsiveness, and can achieve the processing of indolepropionic acid and polyphenols and the stability of oral delivery.

The invention discloses a method for improving the starch digestibility inhibition effect of a spray drying method by using high amylose, and belongs to the technical field of food processing. According to the invention, highland barley glutelin, low-amylose-content corn starch, normal-amylose-content corn starch and high-amylose-content corn starch are selected, and a spray drying technology is used to simulate an embedding structure of protein in a natural grain structure on the surface of starch particles. The method comprises the following steps: dissolving protein in a 0.02% NaOH solution, then adding corn starch with different amylose contents, stirring for 30 minutes, then carrying out spray drying treatment, controlling the addition amount of the protein to be 10% of the total mass of the starch, setting the inlet temperature of a spray dryer to be 170 DEG C, setting the outlet temperature to be 80 DEG C, and controlling the feeding speed of a peristaltic pump to be 35 mL / min; the appearance of the prepared starch sample is similar to the spatial structure in highland barley grains, and the digestibility of the highland barley grains is reduced.

We offer multi-layered noodles that contain high-amylose wheat flour, have good shape retention and separation, and are less prone to becoming crumbly. [Solution] Multi-layer noodles having a laminated structure with layer B disposed between two layers A, wherein the content of high-amylose wheat flour in the total mass of cereal flours and starches in layer A is X% by mass, and the content of high-amylose wheat flour in the total mass of cereal flours and starches in layer B is Y% by mass, where X>Y and 5≦X≦100, and the high-amylose wheat flour is wheat flour with an amylose content of 40% by mass or more in total starch as analyzed by the Concanavalin A method.

The present application relates to electronic glass fiber sizing material technical field, disclose a kind of composite modified starch for electronic glass fiber secondary sizing and its preparation method. With deionized water, high amylose starch, sodium sulfate, sodium hydroxide solution, acrylamide, vinyl acetate and oxidant as main raw material, and introduce low ash hydroxypropyl trimethyl ammonium hydroxypropyl sulfonic acid double ion polyglycerol borate glass affinity modification compound and methoxy polyethylene glycol succinic acid monoester aminopropyl silane amide low ash flexible film-forming modification compound, by suspension dispersion, carbamoyl ethyl modification, composite esterification modification, oxidation viscosity reduction, neutralization, centrifugation, washing, drying and crushing are prepared. The obtained composite modified starch has the characteristics of low ash, good film-forming property, sizing film flexible and transparent, viscosity stability, strong affinity with electronic glass fiber surface, easy desizing and low residual.

The invention belongs to the technical field of starch structure regulation and function modification, and provides a preparation method of heat-resistant and digestion-resistant starch microspheres. The method comprises the following steps: by taking high amylose as a raw material, carrying out acidolysis and debranching treatment to obtain an amylose mixed component, and further carrying out accurate grading on the amylose according to the molecular size through volume exclusion chromatography to obtain an amylose fraction with narrow polymerization degree distribution and uniform chain length. Then recrystallization induction is carried out on the fractions, autoclaving treatment is carried out under the condition that the water content is controlled, amylose molecules are subjected to ordered rearrangement, and the starch microspheres which are compact in structure and high in crystallinity are constructed. The prepared resistant starch microspheres have excellent thermal stability and enzymolysis resistance, and still keep higher resistant starch content after being boiled. The method realizes accurate regulation and control of the chain length of the amylose and synergistic improvement of heat resistance and digestion resistance, is suitable for the fields of functional food and nutrition and health, and has a good application prospect.

The application discloses a caffeic acid-amino acid composite grafted starch and a preparation method and application thereof. The preparation method comprises the following steps: using a catalytic system comprising 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride and 4-dimethylaminopyridine to catalyze caffeic acid to be selectively grafted to primary hydroxyl groups at C6 of high amylose starch, so as to prepare caffeic acid selectively grafted starch; then, amino acid is added to continue the reaction, so as to prepare caffeic acid-amino acid composite grafted starch; and the amino acid mainly reacts with secondary hydroxyl groups at C2 and C3 of the high amylose starch. The composite grafted starch in the application has excellent emulsification stability, gelation characteristics and biological activity by using the synergistic effect between functional groups, the prepared emulsion gel has an encapsulation rate of active substances of more than 93%, a storage stability of more than 90 days, and a significant enhancement of antioxidant capacity, and the inhibition rate of pathogenic bacteria is greater than or equal to 99.9%, so that the composite grafted starch can be widely applied to high-end skin care cosmetics such as face cream and sunscreen cream.

The application provides a probiotic-loaded aerogel-hydrogel composite material and a preparation method thereof. The probiotic-loaded aerogel-hydrogel composite material comprises: a sodium alginate-gelatinized high-amylose starch aerogel; an active ingredient, wherein the active ingredient comprises probiotics, and the active ingredient is at least loaded in the pores of the sodium alginate-gelatinized high-amylose starch aerogel; and a sodium alginate-calcium chloride hydrogel coating, which is coated on the surface of the sodium alginate-gelatinized high-amylose starch aerogel loaded with the active ingredient. The probiotic-loaded aerogel-hydrogel composite material provided by the application can protect the active probiotics from passing through the stomach acid environment smoothly, and stably release the probiotics in the distal intestinal region, i.e., the colon, to achieve controllable release of the probiotics.

The invention belongs to the technical field of rice variety breeding, and particularly relates to a breeding method of a special rice variety for patients with kidney diseases and diabetes mellitus, which comprises the following specific steps: selecting a parent material: taking a low-water-soluble protein mutant variety LGC-1 introduced from a radiation breeding field of the Japanese biological resource research institute as a female parent; the Qingyou 308 rice variety bred by Institute of Rice Institute of Academy of Agricultural Sciences in Fujian Province is used as a male parent for hybridization; hybrid progenies are obtained through hybridization, selfing is carried out, progeny seeds are analyzed from F1, and seeds with low glutelin characters and high alcohol-soluble protein characters are screened out; selecting seeds with low glycemic index from the seeds with low glutelin character and high prolamin character; seeds with high amylose content are selected from the seeds with the low glycemic index. The breeding method has the advantages that the bred seeds can be suitable for kidney patients and also suitable for diabetics.

The invention discloses a rice ferritin mutant with improved thermal stability, a coding gene and application of the rice ferritin mutant, the mutant is rice ferritin, an extended peptide EP segment amino acid sequence of the mutant is replaced by an EP segment amino acid sequence of soybean ferritin, and the thermal stability of the rice ferritin is improved; after the gene encoding the mutant is introduced into rice, the head rice rate of transgenic rice grains is increased, the chalkiness degree is reduced, the total starch content and amylose content are increased, the total protein content and the soluble sugar content are reduced, the iron content of the transgenic rice grains is remarkably increased, the iron content of cooked rice is increased by 1.57-1.95 times compared with that of wild rice, and the rice quality is improved. The problem of serious iron loss of natural ferritin in the cooking process is partially solved. The thermal stability of the obtained rice ferritin is remarkably improved, and the rice ferritin can be directly used for producing high-quality polished rice, can also be used as a raw material for preparing functional foods such as high-iron high-amylose rice flour and low-glycemic-index rice products, and has important industrialization value and wide market application prospects.

The invention discloses caffeic acid-amino acid composite grafted starch as well as a preparation method and application thereof. The preparation method comprises the following steps: catalyzing caffeic acid to be selectively grafted to C6 primary hydroxyl of high amylose by adopting a catalytic system containing 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride and 4-dimethylaminopyridine, so as to prepare caffeic acid selectively grafted starch; then amino acid is added for continuous reaction, and caffeic acid-amino acid composite grafted starch is prepared; wherein the amino acid mainly reacts with secondary hydroxyl groups at C2 and C3 positions of high amylose. The composite grafted starch utilizes the synergistic effect among functional groups and has excellent emulsification stability, gelation characteristic and biological activity, the encapsulation efficiency of the prepared emulsion gel on active substances is 93% or above, the storage stability exceeds 90 days, the oxidation resistance is remarkably enhanced, the inhibition rate on pathogenic bacteria is larger than or equal to 99.9%, and the prepared emulsion gel has good stability. The composition can be widely applied to high-end skin care cosmetics such as face cream and sunscreen cream.

This invention belongs to the field of rice molecular breeding, specifically relating to a method for cultivating rice with high resistant starch content; it constructs... SS3a and SS3b Gene co-knockout vectors were created and screened using Agrobacterium-mediated methods to obtain simultaneous knockouts. SS3a and SS3b A new rice germplasm containing the gene; sequencing results of PCR amplification products showed that the target rice contained... SS3a and SS3b All genes underwent frameshift mutations, resulting in complete loss of function; digestibility and physicochemical quality analysis results showed that... SS3a and SS3b The gene co-knockout significantly increased the resistant starch content and significantly reduced the digestibility of rice, while also exhibiting significant changes in physicochemical qualities, resulting in a marked improvement in its nutritional and health benefits. Applying the method for cultivating high-resistant starch rice and related genetic materials of this invention to rice breeding practices is expected to bring new breakthroughs in the selection of nutritious and healthy new rice varieties.

The invention discloses a ternary drug loading system based on double modified high amylose and a preparation method and application thereof. The preparation method comprises the following steps: modifying high amylose by adopting medium and short chain fatty acid to prepare medium and short chain fatty acid modified high amylose; performing plasma surface treatment on the medium and short chain fatty acid modified high amylose starch to prepare double modified high amylose starch; mixing idebenone, bakuchiol, squalane and an oil substance to form an oil phase, mixing the dual-modified high-amylose starch with water to form a water phase, mixing the oil phase with the water phase, and carrying out homogenization treatment to prepare a drug-loaded Pickering emulsion; and carrying out standing and curing treatment on the drug-loaded Pickering emulsion at room temperature, so as to prepare the ternary drug-loaded system based on the double modified high amylose. According to the invention, the basic hydrophobicity is endowed through chemical modification, and the surface gradient is constructed through physical modification, so that the selective encapsulation of active components is realized.

The invention relates to the technical field of food production, and particularly discloses a method for producing a gas-containing rice fermented beverage, which comprises the following steps: raw material pretreatment, gelatinization, enzymolysis and saccharification, filtration and cooling, yeast activation and inoculation, segmented temperature control fermentation, filling and pasteurization. By adopting a closed pure yeast fermentation process, the risk that infectious microbes are introduced in traditional open solid state fermentation is avoided, and the purity of the fermentation process is ensured, so that the possibility that the product is polluted by microorganisms is reduced, and the batch-to-batch consistency of physicochemical indexes of the final product is improved; the rice with high amylose content is used as a raw material, so that the sticky mouth feeling caused by high amylose is avoided, and a refreshing and smooth mouth feel foundation of the product is laid.

To provide dried noodles that contain high-amylose wheat flour and exhibit reduced powderiness in texture.SOLUTION: A method for producing dried noodles comprises drying raw noodles at 70°C or higher, the raw noodles containing 30 to 100 mass% of high-amylose wheat flour in the total mass of cereal flour and starch, the high-amylose wheat flour being a wheat flour having an amylose content of 40 mass% or more in total starch as analyzed by the Concanavalin A method.SELECTED DRAWING: None

To provide dried noodles that contain high-amylose wheat flour and exhibit good texture.SOLUTION: A method for producing dried noodles comprises drying raw noodles containing 30 mass% or more of high-amylose wheat flour in the total mass of cereal flour and starch, the high-amylose wheat flour being a wheat flour having an amylose content of 40 mass% or more in total starch as analyzed by the Concanavalin A method, and the high-amylose wheat flour having a damaged starch amount of 4.0 to 6.3 mass% as measured by the AACC Method 76-31.SELECTED DRAWING: None

The invention provides an aerogel-hydrogel composite material loaded with probiotics and a preparation method of the aerogel-hydrogel composite material. The aerogel-hydrogel composite material loaded with the probiotics is prepared from sodium alginate-gelatinized high amylose aerogel, and the probiotics are prepared from sodium alginate-gelatinized high amylose aerogel, sodium alginate-gelatinized high amylose aerogel and sodium alginate-gelatinized high amylose aerogel. The active component comprises probiotics, and the active component is at least loaded in a pore channel of the sodium alginate-gelatinized high amylose aerogel; the surface of the sodium alginate-gelatinized high amylose aerogel loaded with the active component is coated with the sodium alginate-calcium chloride hydrogel coating. According to the aerogel-hydrogel composite material loaded with the probiotics, the active probiotics can be protected to smoothly pass through the acid environment of the stomach, the probiotics are stably released at the colon part of the far-end area of the intestinal tract, and controllable release of the probiotics is achieved.

The present application relates to a method for increasing the amylose content and stress resistance of corn by overexpressing sucrose synthase gene, the method is to overexpress sucrose synthase gene ZmSUS1 in corn to obtain transgenic corn with high amylose content and high stress resistance, the nucleotide sequence of the sucrose synthase gene ZmSUS1 is shown as SEQ ID NO. 1. The present application overexpresses sucrose synthase gene ZmSUS1 in corn, effectively provides precursor substances for the biosynthesis of amylose, so that the corn overexpressing sucrose synthase gene ZmSUS1 has 41.1-69.2% higher amylose content than normal corn kernels, significantly increasing the amylose content in corn kernels. And the transgenic corn obtained by the method of the present application shows obvious drought resistance, confirming that the method of the present application is a green, efficient and sustainable effective way to solve the stable yield or less yield of corn under drought and water stress, and has a wide application prospect.

This application relates to the field of oil drilling fluid treatment agents, and in particular to a modified starch filtration loss reducer for drilling fluids and its preparation method. A method for preparing a modified starch filtration loss reducer for drilling fluids includes the following steps: S1. Pre-crosslinking activation: High amylose starch is formulated into an emulsion, a composite crosslinking agent is added for reaction, and the mixture is dried under negative pressure; S2. Nano-inorganic hybrid composite: A nano-reinforcing phase and layered bimetallic hydroxide are added, and high-speed dispersion is performed to form a three-phase rigid network; S3. Slow-release low-temperature negative pressure alkalization: A slow-release composite alkali is added, and water is removed under controlled temperature and negative pressure; S4. Double etherification modification: An anionic etherifying agent and a cationic etherifying agent are combined for etherification; S5. Directional grafting polymerization: AMPS-type monomers are added for grafting, and the mixture is dried, pulverized, and sieved to obtain the finished product. Through five synergistic modifications, an organic-nano-inorganic three-phase rigid network is progressively constructed on the starch molecules, enabling the product to maintain structural integrity at high temperatures and significantly reducing high-temperature and high-pressure filtration loss.

The invention provides application of indolepropionic acid (IPA) in preparation of a product for preventing and treating alcoholic liver injury, and relates to the technical field of medicines. The invention discloses indolepropionic acid or starch ester indolepropionylated high amylose corn starch (HAMSIPA) for the first time, which can be used for remarkably relieving alcoholic liver injury, improving liver functions, liver fatty degeneration and liver oxidative stress of individuals with alcoholic liver injury, protecting intestinal barrier injury of the individuals with alcoholic liver injury, and improving the intestinal barrier injury of the individuals with alcoholic liver injury. And intestinal lipopolysaccharide (LPS) is prevented from leaking out and entering the hepatic portal vein, so that the activation of a liver inflammatory pathway is inhibited, and finally, the intestinal liver axis homeostasis is maintained. The indolepropionic acid has a wide application prospect in the aspect of alcoholic liver injury, and the application scene of indolepropionic acid is widened.

The invention discloses an Etch1 protein related to plant resistant starch as well as a coding gene and application thereof. The Etch1 protein is a protein with the following amino acid sequence: 1) a protein with an amino acid sequence as shown in SEQ ID NO: 1; results show that the coding gene of the Etched1 protein can increase the content of resistant starch and the content of amylose in grains and change the structure of starch, and a new gene resource is provided for breeding of corn with high resistant starch or high amylose; the coding gene of the Etched1 protein can be used for breeding corn varieties with high resistant starch and high amylose through molecular marker-assisted breeding, gene editing breeding and a genetic engineering method, and a powerful means is provided for starch improvement and grain traits improvement of corn seeds.

The invention discloses an antibacterial degradable meal box material and a preparation method thereof, and belongs to the field of degradable materials. The antibacterial degradable meal box material comprises the following raw materials in parts by mass: 25-40 parts of polylactic acid, 30-60 parts of high amylose, 10-15 parts of modified bamboo powder fibers, 1-3 parts of a plasticizer, 0.5-2 parts of an antioxidant and 0.5-2 parts of a lubricant, and polydopamine-epoxy silane is compounded on the modified bamboo powder fibers. Wherein the linear structure of the high amylose can help molecular chains to be better oriented and arranged, improve the tightness of molecular arrangement and help to improve the heat resistance and mechanical strength of the material. The bamboo powder fiber as a reinforcing phase can improve the impact resistance and tensile strength of the composite material, and after modification, the bamboo powder fiber can be used as a bridge of a matrix material, so that the compatibility and binding force between the bamboo powder fiber and the matrix and between the matrixes are improved, and the mechanical strength of the degradable material is improved.

This invention belongs to the field of starch processing, specifically relating to a method for improving the intestinal microbial utilization rate of high amylose. The method is achieved through the following steps: high amylose pretreatment; low-temperature plasma treatment; spraying with a hydrophobicating agent; washing and centrifuging drying. This invention, by immersing high amylose in the plasma, allows divalent metal ions to be retained on the surface and inside the high amylose granules, enhancing the etching effect of the low-temperature plasma on the high amylose granules and significantly improving the surface roughness of the high amylose granules, thereby promoting the residence time of intestinal microorganisms on the high amylose granules. The low-temperature plasma treatment, using a mixed gas, introduces fluorinated ethane groups onto the starch surface, providing initial hydrophobicity. It also provides reaction sites for subsequent hydrophobication. Shorter-range hydrophobic groups can improve the adhesion and fixation ability of proteins on the surface of intestinal microbial cells, thus improving the utilization rate of intestinal microorganisms.

This invention relates to the field of food preservation technology, specifically to a starch-chlorogenic acid-xanthan gum composite preservative coating liquid, its preparation method, and its application. The starch-chlorogenic acid-xanthan gum composite preservative coating liquid comprises the following components by mass percentage: high amylose; chlorogenic acid; xanthan gum; glycerol; and the balance being water. The beneficial effects of this invention are: the coating liquid of this invention specifically uses lotus seed starch with high amylose content as a matrix, chlorogenic acid as a functional active molecule, and xanthan gum as a freeze-thaw stabilizer, and is prepared through a multi-stage pressure-progressive high-pressure homogenization technology, effectively overcoming technical difficulties such as the easy aging and retrogradation of high amylose, the easy deactivation of polyphenolic active substances during processing, and the poor freeze-thaw stability of the composite system. It is particularly suitable for the preservation of perishable foods such as seafood, and can effectively extend shelf life.

The invention belongs to the technical field of batteries, and particularly relates to a preparation method of an iodine positive electrode protection material in a battery and application of the iodine positive electrode protection material in a zinc-iodine battery. According to the invention, high amylose is used as a raw material, and the recombinant high amylose is prepared through the processes of dissolution, alcohol precipitation, drying and the like and is used as a positive electrode protection material of a battery. After being mixed with iodine, sodium carboxymethyl cellulose, ketjen black and the like, the zinc-iodine compound can be prepared into a positive plate of a battery, and the positive plate and other battery parts are assembled into a zinc-iodine rechargeable battery, so that the shuttle effect of multiple iodine ions when iodine is used as the positive electrode of the battery is inhibited. According to the zinc-iodine battery prepared by the method disclosed by the invention, the charge-discharge cycle stability and the rate stability are remarkably improved.

The invention belongs to the field of biochemical engineering and food engineering, and particularly relates to a method for preparing high-purity amylose with different molecular weights from high amylose based on enzymolysis regulation and control in a directional high-yield manner. The method comprises the following steps: deproteinization primary purification, fat removal primary purification, debranching treatment, pullulanase regulation and control, amylose crude separation and amylose purification. And finally, the amylose with the purity of more than or equal to 95% and controllable molecular weight can be obtained, and the method has high yield and industrial feasibility, and has wide application prospects.