The invention relates to the field of food, and particularly discloses a making method of a squid-lotus root cake. The making method comprises the following steps of adding squid mince onto the upper part of a lotus root slice of a seasoned lotus root to tightly cover the lotus root slice in an arc-shaped manner, uniformly sprinkling wheat weak flour at the exterior of the squid mince, uniformly wrapping the exterior of a semi-finished product with paste, finally, uniformly sprinkling a breadcrumb, heating palm oil to 160 DEG C, adding the squid-lotus root cake obtained in the steps into the heated palm oil, frying the squid-lotus root cake, taking out a semi-finished-product squid-lotus root cake when the semi-finished-product squid-lotus root cake is golden yellow, bleeding redundant oil, then quick-freezing the semi-finished-product squid-lotus root cake to obtain the finished-product squid-lotus root cake, sub-bagging the finished-product squid-lotus root cake, and carrying out refrigerated storage. By using the making method, a squid and the lotus root are perfectly combined; the squid-lotus root cake has a quite good satiety effect and nutrient value when being used during hunger, and can have effects of improving malnutrition, eliminating pathogenic heat from the blood, reducing lipid absorption, invigorating the spleen to arrest diarrhea, relieving inappetence, promoting skeletal development, treating anemia, relieving fatigue, restoring vision, improving liver, resisting a virus and resisting a ray, and the like when being used as a snack at ordinary times.