Systems and methods to determine patient's responsiveness to alveolar recruitment maneuver

A lung recruitment and patient technology, applied in the fields of application, drug equipment, medical science, etc., can solve the problems of hemodynamic weakening in expiratory pause, long inhalation, etc.

Pending Publication Date: 2020-09-25
TIMPEL MEDICAL BV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, CT provides only static images, requires the use of excess radiation (the entire lung must be scanned at at least two different PEEP levels), and it requires long inspiratory / expiratory pauses (with hypercapnia and hemodynamic risk of weakening)
Finally, patients must be transported from the ICU to the radiology department, which presents well-known risks

Method used

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  • Systems and methods to determine patient's responsiveness to alveolar recruitment maneuver
  • Systems and methods to determine patient's responsiveness to alveolar recruitment maneuver
  • Systems and methods to determine patient's responsiveness to alveolar recruitment maneuver

Examples

Experimental program
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Effect test

Embodiment approach 1

[0129] Embodiment 1. A method for determining a potential lung recruitment value in a patient, the method comprising: measuring a first end-expiratory lung pressure in at least one region of the lung during an applied first positive end-expiratory pressure Impedance; during the applied second positive end-expiratory pressure, measuring a second end-expiratory lung impedance in the at least one region of the lung; a change in end-expiratory lung impedance between said impedance measurements obtained at a positive end-expiratory pressure and said second positive end-expiratory pressure; according to Obtaining impedance measurements to determine a first chordal compliance of said at least one region of said lung; determined from pixels of a second electrical impedance tomography image of said patient at said second positive end-expiratory pressure a second chord compliance of the at least one lung of the patient; and determining the at least one region of the lung from impedance ...

Embodiment approach 2

[0130] Embodiment 2. The method of embodiment 1, further comprising: determining said at least one chord representative of said lung based on said first chord compliance observed during said first positive end-expiratory pressure. A first index of the end-tidal lung impedance change in the region.

Embodiment approach 3

[0131] Embodiment 3. The method of embodiments 1 and 2, further comprising: based on the pressure difference between the first positive end-expiratory pressure and the second positive end-expiratory pressure and based on describing elastic lung behavior The above-predicted or below-predicted second index representing a change in lung compliance in the at least one region of the lung is determined using the equation of the lung.

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Abstract

A system and method for determining a potential lung recruitment value for a patient that includes during an applied first positive end expiratory pressure (PEEP) to the lungs of the patient, measuring a first end expiratory lung impedance (EELZ) of the lungs at the first PEEP; during an applied second PEEP, measuring a second EELZ at the second PEEP, determining a change in EELZ between the firstPEEP and the second PEEP, determining a first chord-compliance of the lungs from pixels of a first electrical impedance tomography (EIT) image of the patient at the first PEEP, determining a second chord-compliance from a second EIT image of the patient at the second PEEP, determining a first index representing the change in EELZ, determining a second index representing a change in compliance, and based on the first index and the second index, determining a potential lung recruitment value for the patient.

Description

[0001] priority claim [0002] This application claims the benefit of U.S. Provisional Patent Application Serial No. 62 / 629,466, filed February 12, 2018, the disclosure of which is hereby incorporated by reference in its entirety under 35 U.S.C. § 119(e) way incorporated into this article. technical field [0003] The present disclosure relates to systems and methods for determining a patient's recruitment potential of a patient's lung volume through an alveolar recruitment procedure. In particular, the present disclosure relates to systems and methods that include and utilize electrical impedance tomography (EIT) systems to determine a patient's recruitment potential. Background technique [0004] Treatment of acute respiratory distress syndrome ("ARDS") includes an appropriate strategy of mechanical ventilation. Alveolar Recruitment Manipulation ("ARM") is an intervention applied in cases of moderate to severe ARDS. ARM is a temporary and controlled increase in mechanic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M16/00A61B5/053A61B5/08
CPCA61B5/6831A61B5/087A61B2562/0247A61M2205/50A61M2230/46A61M2230/65A61M16/026A61B5/085A61B5/0536A61B5/6823A61M16/205A61M2016/0036A61M2016/0027A61M2016/102A61B5/7275A61M2205/3327A61M16/0003A61M16/024A61B5/0803
Inventor 拉斐尔·霍扎克
Owner TIMPEL MEDICAL BV
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