Application of total saponins of American ginseng stems and leaves in the preparation of a composition for combating bone loss caused by weightlessness
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- 63919 TROOPS PLA
- Publication Date
- 2022-05-20
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Abstract
Description
technical field
[0001] The invention relates to the technical field of biomedicine, in particular to the application of total saponins from stems and leaves of American ginseng in the preparation of a composition for combating bone loss. Background technique
[0002] During long-term space flight, bone loss occurs as a result of the combined effects of increased bone resorption and decreased bone formation. In microgravity, the rate of bone loss is more than 10 times the monthly loss of bone density in postmenopausal women on the ground. Bone density lost during a 6-month space flight is largely regained about 1,000 days after returning to Earth. However, the structural changes are irreversible, similar to those that occur in senile osteoporosis. In a series of adaptive changes in the human body in the microgravity environment, most of the system changes are self-limiting, and only the changes in the skeletal system show a progressive process. The detection of the bone de...