Detection system based on Mueller matrix imaging
A detection system and imaging technology, applied in the direction of polarization influence characteristics, etc., can solve the problems of long imaging time, large errors introduced into the system, and many polarization devices, etc., to optimize the response time, shorten the detection time, and facilitate automatic control.
Pending Publication Date: 2020-11-17
CHINA JIUYUAN HI TECH EQUIP
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Problems solved by technology
[0005] However, this method needs to control a large number of rotating polarization devices, which is inconvenient for automatic programming control, and the single imaging time is longer and the system introduces larger errors
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Embodiment 1
[0023] Such as figure 1 As shown, a detection system based on Mueller matrix imaging includes: a light source 1, 2 groups of collimating lenses, a polarizer, an analyzer, an image acquisition device 11 and a PLC control module 13;
[0024] The light source 1 is used to generate LED light; the 2 groups of collimating lenses are used to collimate the LED light, and the 2 groups of collimating lenses include: a collimating lens 2 arranged in sequence along the illumination direction of the LED light and a light appendix3.
[0025] In this embodiment, the polarizing device is used to modulate the collimated LED light into polarized light and irradiate the tissue section 7 to be tested; the polarizing device includes The first linear polarizing plate 4 and the first electrically controlled rotating platform 5 are installed secondly, and the first 1 / 4 wave plate 6 is arranged on the first electrically controlled rotating platform 5 .
[0026] The polarization analyzer is used to a...
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Abstract
The invention discloses a detection system based on Mueller matrix imaging, and belongs to the technical field of biological tissue optics. The detection system comprises a light source which is usedfor generating LED light; a collimating lens group, wherein the collimating lens group is used for collimating the LED light; a polarizing device which is used for modulating the collimated LED lightinto polarized light and irradiating the polarized light onto a tissue slice to be detected; a polarization analyzing device which is used for analyzing the polarized light scattered by the tissue slice to be detected; and an image acquisition device which is used for acquiring the light intensity images passing through the polarization analysis device in different polarization states and uploading the acquired light intensity images to the computer. By directly observing a Mueller matrix image of an unstained canceration tissue pathological section measured by a system, the canceration tissueand the normal tissue are distinguished.
Description
technical field [0001] The invention relates to the technical field of biological tissue optics, in particular to a detection system based on Mueller matrix imaging. Background technique [0002] Polarization imaging technology has great development prospects in the field of biomedicine. Based on the idea and method of the early polarization "gating" technology, it has been developed to use polarization difference and degree of polarization imaging and rotational linear polarization imaging technology to achieve auxiliary detection of superficial cancerous tissue to a certain extent. The polarization characteristics are relatively simple. [0003] Rapid pathological detection has become an important application point of clinical pathological detection. Since ordinary optical microscopes can only judge the difference between cancerous tissue and normal tissue by observing the stained slices, the staining of pathological slices will increase the time of pathological detection...
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IPC IPC(8): G01N21/21
CPCG01N21/21
Inventor 田博文张明磊闫鹏宇云宇
Owner CHINA JIUYUAN HI TECH EQUIP