Kidney-protecting probiotic composition

A probiotics and composition technology, applied in the field of kidney-protecting probiotics composition, can solve the problems of no cure or prevention strategy, lack of treatment methods for end-stage renal disease, etc. Effect

Pending Publication Date: 2020-12-01
上海泓商生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no cure or prevention strategy for CKD, and timely treatment is extremely challenging due to the lack of symptoms in the early stages of

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Kidney-protecting probiotics composition, including Lactobacillus acidophilus, Bifidobacterium longum, Bifidobacterium bifidum combined with xylo-oligosaccharide powder, said Lactobacillus acidophilus, Bifidobacterium longum, Bifidobacterium bifidum combined with oligomer The effective amount of xylose powder is a daily supplement of 15 billion, that is, 0.5*10 10 Lactobacillus acidophilus cfu / day, 0.5*10 10 cfu / day of Bifidobacterium longum and 0.5*10 10 cfu / day of Bifidobacterium bifidum and 0.5 grams of xylo-oligosaccharide powder per day.

Embodiment 2

[0018] Kidney-protecting probiotics composition, including Lactobacillus acidophilus, Bifidobacterium longum, Bifidobacterium bifidum combined with xylo-oligosaccharide powder, said Lactobacillus acidophilus, Bifidobacterium longum, Bifidobacterium bifidum combined with oligomer The effective amount of xylose powder is a daily supplement of 30 billion, that is, 1.0*10 10 Lactobacillus acidophilus cfu / day, 1.0*10 10 cfu / day of Bifidobacterium longum and 1.0*10 10 cfu / day of Bifidobacterium bifidum and 1.0 g of xylo-oligosaccharide powder per day.

Embodiment 3

[0020] Kidney-protecting probiotics composition, including Lactobacillus acidophilus, Bifidobacterium longum, Bifidobacterium bifidum combined with xylo-oligosaccharide powder, said Lactobacillus acidophilus, Bifidobacterium longum, Bifidobacterium bifidum combined with oligomer The effective amount of xylose powder is a daily supplement of 45 billion, that is, 1.5*10 10 Lactobacillus acidophilus cfu / day, 1.5*10 10 cfu / day of Bifidobacterium longum and 1.5*10 10 cfu / day of Bifidobacterium bifidum and 1.5 grams of xylo-oligosaccharide powder per day.

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PUM

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Abstract

The invention discloses a kidney-protecting probiotic composition, and belongs to the field of all related food industries of probiotics. The composition comprises lactobacillus acidophilus, bifidobacterium longum, bifidobacterium bifidum and xylooligosaccharide powder. The kidney-protecting probiotic composition disclosed by the invention is a composition of probiotics and prebiotics, and can beused for effectively regulating blood pressure and relieving kidney blockage. Meanwhile, the yield of short-chain fatty acid is increased, the levels of blood urea nitrogen, serum creatinine and urinary albumin are reduced, the condition of renal fibrosis is improved, the inflammatory reaction of the kidney is inhibited, and the progress of kidney diseases is further relieved. Through the combination of the probiotics and the prebiotics, the composition can help a human body to regulate intestinal flora, and is a food supplement or medicine which can be safely taken for a long time and can effectively improve chronic kidney diseases.

Description

technical field [0001] The invention relates to a kidney-protecting probiotic composition, which belongs to all relevant food industry fields of probiotics. Background technique [0002] Chronic kidney disease (CKD) affects about 10% of the world's population and causes an annual economic impact of about $48 billion in the United States alone (Jha V, 2013). Hypertension is an important risk factor for CKD, and approximately 85% - 90% of CKD stage 3 patients have hypertension (Rao M V, 2008). Chronic hypertension leads to high intra-glomerular pressure, which in turn impairs glomerular filtration (Taler S J, 2013). Therefore, lowering blood pressure is an important and widely used approach to slow the progression of CKD. At present, the early treatment of CKD mainly focuses on controlling blood pressure, reducing protein and salt intake, preventing acute kidney injury and controlling blood sugar (Inker L A, 2014). There is no cure or prevention strategy for CKD, and timely...

Claims

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Application Information

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IPC IPC(8): A61K35/747A61K35/745A61K31/702A61P13/12A23L33/135A23L33/125
CPCA61K35/747A61K35/745A61K31/702A61P13/12A23L33/135A23L33/125A23V2002/00A61K2300/00A23V2200/30A23V2200/3202A23V2200/3204A23V2250/28
Inventor 潘逸萱
Owner 上海泓商生物科技有限公司
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