Magnetic control generation method of nano reactor
A nano-reactor and magnetron technology, applied in the field of biochemistry, can solve the problems of non-uniform vesicle size and inability to precisely control the size, and achieve the effect of solving the non-uniform size of vesicles
Active Publication Date: 2020-12-01
YISHANG TOMORROW TECH
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Problems solved by technology
[0007] The inventors applied this new discovery to the preparation of nanoreactors. By controlling the strength of the magnetic field, the microvesicles obtained by the self-assembly of magnetic molecules can be divided into two, four in half, eight in four, etc. under the control of the magnetic field. Multiple magnetically controlled passive splitting process, so as to obtain nano-scale vesicles with uniform size and precise size control, so as to solve the technical problems in the prior art that the vesicle size is not uniform and the size cannot be precisely controlled
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[0029] Microvesicles self-assembled by magnetic molecules will deform under the action of an external magnetic field. If the magnetic field is strong enough, the vesicles will split. We call this splitting as passive splitting of vesicles. The minimum magnetic field strength required for passive vesicle splitting is called the splitting magnetic field strength, with B d indicated that apparently the fragmentation magnetic field strength is related to the size of the vesicle. The splitting of a microvesicle into nanovesicles is a multiple magnetically controlled passive splitting process of splitting into two, splitting into four, splitting into four, etc., and the strength of the splitting magnetic field corresponding to the i-th split is expressed as B d,i .
[0030] figure 1 The four states of vesicle splitting in two under the control of magnetic field are shown.
[0031] a is the shape of the vesicle when there is no external magnetic field; b is the shape of the vesicl...
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Abstract
The invention discloses a generation method of a nano reactor, and belongs to the field of biochemistry. The method comprises the following steps: 1, preparing a magnetic vesicle; 2, applying a magnetic field to the magnetic vesicle so that the vesicle deforms under the action of magnetic field force; 3, enabling the magnetic vesicle to have magnetic control splitting by controlling the magnetic field intensity of the magnetic field; and 4, obtaining a plurality of vesicles with the radius of less than 1 micron through one or more magnetic control splitting to be used as the nano reactor. Thetechnical problem in the prior art that the nano reactor uniform in size and capable of accurately controlling the size cannot be prepared is solved.
Description
technical field [0001] The invention belongs to the field of biochemistry, and in particular relates to a method for forming a nanoreactor, in particular to a method for obtaining a nanoreactor by using vesicles obtained by magnetic molecule self-assembly to perform magnetic control splitting. Background technique [0002] Vesicles or liposomes refer to some natural or synthetic surfactants and some phospholipids that cannot simply associate into micelles when dispersed in water, but spontaneously form a closed bilayer structure. The shape of the vesicles is mostly spherical, ellipsoidal or oblate. [0003] The important application of vesicles is to create a reaction microenvironment, so that the reaction components with different polarities have the opportunity to contact each other properly. In the microreactor, the chemical reaction is controlled in a small microspace, which is different from the conventional reaction. Compared with the reactor, it has more features, su...
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Login to View More IPC IPC(8): B01J19/00
CPCB01J19/0093B01J2219/00846B01J2219/00864
Inventor 舒咬根罗永涛
Owner YISHANG TOMORROW TECH