Preparation system and method of polyglycolic acid

Abstract

The invention provides a preparation system and method of polyglycolic acid. The preparation system comprises a hydrogenation reactor, a hydrogen feeding pipeline, a hydrolysis reactor and a water vapor feeding pipeline, wherein an oxalate feeding pipeline is arranged on the side wall of the hydrogenation reactor, a micro-interface unit is arranged in the hydrogenation reactor, and the micro-interface unit is formed by sequentially arranging a plurality of micro-interface generators from top to bottom; and the hydrogen feeding pipeline penetrates through the side wall of the hydrogenation reactor and enters the micro-interface unit, so that hydrogen is crushed into micron-sized micro-bubbles in the micro-interface unit in advance before hydrogenation reaction. According to the preparationsystem disclosed by the invention, the micro-interface unit is arranged in the hydrogenation reactor, and the micro-interface generators are arranged in the hydrolysis reactor, so that hydrogen is crushed into micro-bubbles before hydrogenation reaction of hydrogen and dimethyl oxalate, and the phase boundary mass transfer area between hydrogen and dimethyl oxalate is increased; and meanwhile, thephase boundary mass transfer area in the hydrolysis reaction process is increased.

Description

technical field [0001] The invention relates to the field of preparation of polyglycolic acid, in particular to a preparation system and method of polyglycolic acid. Background technique [0002] Polyglycolic acid is a common biodegradable polyester widely used in high value-added fields such as surgical sutures, drug carriers and bone materials. Polyglycolic acid has a simple and regular linear molecular structure and is a simple linear aliphatic polyester. Polyglycolic acid with a molecular weight over 10,000 has strong mechanical strength and can be used in medical sutures. The industrial preparation of high molecular weight polyglycolic acid usually adopts the method of ring-opening polymerization of glycolide. [0003] China is a country with less oil and more coal. With the development of my country's coal-to-ethylene glycol industry, the use of intermediate product dimethyl oxalate to produce polyglycolic acid on a large scale can further promote the development of ...

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Problems solved by technology

[0007] The first object of the present invention is to provide a preparation system of polyglycolic acid, which can break hydrogen gas into micro-particles before the hydrogenation reaction between hydrogen gas and dimethyl oxalate by setting a micro-interface unit inside the hydrogenation reactor. Bubbles increase the mass transfer area of ​​the phase boundary between hydrogen and dimethyl oxalate, thereby solving the problem of high reaction pressure and large hydrogen-to-ester ratio due to the inability of hydrogen and dimethyl oxalate to be fully mixed inside the reactor in the prior art , The problem of low liquid hourly space velocity

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