Skin wounded area protecting composition and preparation method therefor

A technology for skin wounds and compositions, applied in the medical field, can solve problems such as easy peeling, high irritation, and poor film-forming performance, and achieve good adhesion and flexibility, good protection, and short film-forming time Effect

Inactive Publication Date: 2020-12-15
SHAANXI BIO REGENERATIVE MEDICINE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Aiming at the current liquid bandage products on the market, there are still several core problems. 1. The product forms a film quickly, but a large amount of volatile organic reagents are added, which is more irritating and tingling when used; 2. The film-forming perfor

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The present embodiment provides a skin wound protection composition, comprising the following materials in parts by weight:

[0032] 6.5 parts of film former, 84.5 parts of solvent, 8 parts of plasticizer, 1.0 part of humectant;

[0033] Wherein, the film-forming agent is ethyl cellulose with a content of 6.5 parts; the solvent is a mixture of ethanol, ethyl acetate and hexamethyldisiloxane, wherein the content of ethanol is 37.5 parts, and the content of ethyl acetate is 20 parts. Parts, 27 parts of hexamethyldisiloxane content; The plasticizer is a mixture of glycerin and polyphenylmethylsiloxane, wherein 2 parts of glycerin content, 6 parts of polyphenylmethylsiloxane content; The moisturizing agent is a mixture of propylene glycol and 1,3-butanediol, wherein the content of propylene glycol is 0.5 parts, and the content of 1,3-butanediol is 0.5 parts.

Embodiment 2

[0035] The present embodiment provides a skin wound protection composition, comprising the following materials in parts by weight:

[0036] 11.5 parts of film former, 80 parts of solvent, 7 parts of plasticizer, 1.5 parts of humectant;

[0037] Wherein, the film-forming agent is an acrylic acid copolymer, and its content is 11.5 parts, and the acrylic acid copolymer is butyl methacrylate, dimethylaminoethyl methacrylate and methyl methacrylate copolymer; The solvent is a mixture of isooctane and hexamethyldisiloxane, wherein the content of isooctane is 35 parts, and the content of hexamethyldisiloxane is 45 parts; the plasticizer is a mixture of glycerin and castor oil, wherein glycerin The content is 2 parts, and the content of castor oil is 5 parts; the moisturizing agent is propylene glycol, and its content is 1.5 parts.

Embodiment 3

[0039] The present embodiment provides a skin wound protection composition, comprising the following materials in parts by weight:

[0040] 8.5 parts of film former, 87 parts of solvent, 4 parts of plasticizer, 0.5 part of humectant;

[0041] Wherein, the film-forming agent is polyvinyl butyral, and its content is 8.5 parts; the solvent is a mixture of ethanol, isopropanol, and isooctane, wherein the content of ethanol is 25 parts, and the content of isopropanol is 37 parts. The content of isooctane is 25 parts; the plasticizer is a mixture of glycerin, triethyl citrate and polyphenylmethylsiloxane, wherein the content of glycerin is 1 part, the content of triethyl citrate is 1.5 parts, poly The content of phenylmethylsiloxane is 1.5 parts; the moisturizing agent is sorbitol, and its content is 0.5 parts.

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PUM

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Abstract

The invention provides a skin wounded area protecting composition and a preparation method therefor. The skin wounded area protecting composition comprises the following ingredients in parts by weight: 4-15 parts of film former, 60-90 parts of solvent, 0.5-10 parts of plasticizer and 0.2-8.0 parts of humectant, wherein the film former is selected from one or more of ethyl cellulose, hydroxyethyl cellulose, nitrocellulose, polyvinyl acetate, polyvinyl formal, polyvinyl formal acetal, polyvinyl alcohol carboxyl butyraldehyde and an acrylic copolymer. The wounded area protecting composition has excellent properties, is short in film forming time, low in irritation, uniform and elastic in film, high in degree of comfort, good in waterproofing performance and good in air permeability and can beapplied to protection and nursing of various shallow wounded areas such as scratch, incised wounds and mild burn and scald; and the preparation method is simple and easy in operation and relatively low in cost, facilitates industrialization and has a good application prospect.

Description

technical field [0001] The invention belongs to the field of medical technology, and in particular relates to a skin wound protection composition and a preparation method thereof. Background technique [0002] In daily life, human skin will be damaged by various external factors, such as abrasions, scratches, abrasions, burns, scalds, etc. Improper treatment of local injuries may cause varying degrees of inflammatory reactions, resulting in local redness and swelling, and even tissue necrosis or systemic invasive infection in severe cases, which is life-threatening. [0003] At present, care for superficial wounds or small wounds on the body surface such as abrasions, scratches, abrasions, burns, and scalds mainly includes traditional adhesive bandages and new liquid bandages. The characteristics of traditional adhesive bandages are self-evident, and liquid bandages are a new type of high-end functional medical wet dressings, mainly using biocompatible polyurethane PU film,...

Claims

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Application Information

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IPC IPC(8): A61L26/00
CPCA61L26/0061A61L26/0023A61L26/0019A61L26/0014C08L1/28C08L83/04C08L33/08C08L29/14C08L31/04
Inventor 樊杏利
Owner SHAANXI BIO REGENERATIVE MEDICINE CO LTD
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