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Graph dyeing and recombination method of addressable DNA polyhedron topological structure

A topology and polyhedron technology, applied in informatics, computer material science, instruments, etc., to achieve the effects of easy operation, conflict avoidance, and accurate and credible results

Pending Publication Date: 2021-03-26
CHANGAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] While more hierarchies can lead to larger structures, successive rounds of assembly procedure optimization can be prohibitively challenging

Method used

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  • Graph dyeing and recombination method of addressable DNA polyhedron topological structure
  • Graph dyeing and recombination method of addressable DNA polyhedron topological structure
  • Graph dyeing and recombination method of addressable DNA polyhedron topological structure

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Such as figure 1 As shown, taking the DNA regular tetrahedron as an example, the DNA regular tetrahedron is composed of 4 regular triangles, and each regular triangle is decomposed into 3 sides, and the 4 regular triangles are decomposed into 12 sides in total.

[0035] Use color A and color B to color 12 edges, the number of edges corresponding to color A and color B is equal, color A has 6 edges, color B also has 6 edges, and color A corresponds to the first addressable component , color B corresponds to the second addressable component;

[0036] Such as figure 2 As shown, using a plurality of first addressable components and / or a plurality of second addressable components to synthesize a DNA dyeing strand, the DNA dyeing strand corresponds to a number; multiple DNA dyeing strands correspond to multiple numbers one by one , wherein the numbering can be a number, letter, etc., because a mark for identifying the dyed chain, the present invention does not limit the sp...

Embodiment 2

[0043] Take the DNA dodecahedron as an example. The DNA dodecahedron is composed of 12 regular pentagons. Each regular pentagon is decomposed into 5 sides, and the 12 regular pentagons are decomposed into 60 sides in total.

[0044] Use color A and color B to dye 60 edges, the number of edges corresponding to color A and color B is equal, color A has 30 edges, and color B has 30 edges, wherein color A corresponds to the first addressable component, Color B corresponds to the second addressable component;

[0045] Using a plurality of first addressable components and / or a plurality of second addressable components to synthesize a DNA dyeing chain, the DNA dyeing chain corresponds to a number; multiple DNA dyeing chains correspond to multiple numbers one by one;

[0046] Further, multiple DNA dyeing chains are optimized to obtain standard DNA dyeing chains, wherein there are 8 standard DNA dyeing chains.

[0047] DNA polyhedrons are recombined using DNA dyed strands to obtain m...

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Abstract

The invention relates to the technical field of DNA polyhedron dyeing and recombination, in particular to a graph dyeing and recombination method of an addressable DNA polyhedron topological structure, which can solve the problem of conflict between repeatability and addressability in the DNA polyhedron topological structure consisting of repeated components. The graph dyeing method of the addressable DNA polyhedron topological structure comprises the steps that 1, each edge of a DNA polyhedron is dyed through two colors, the number of the edges of the two colors is equal, the edge of each color corresponds to one addressable assembly, and the addressable assemblies comprise the first addressable assembly and the second addressable assembly; 2, a plurality of first addressable assemblies and / or a plurality of second addressable assemblies are / is utilized to synthesize a DNA staining chain, and the DNA staining chain corresponds to a serial number, wherein the plurality of DNA stainingchains are in one-to-one correspondence with a plurality of numbers; and 3, the plurality of DNA staining chains are optimized to obtain a standard DNA staining chain. The method is used for graph dyeing and recombination of the addressable DNA polyhedron topological structure.

Description

technical field [0001] The invention relates to the technical field of DNA polyhedron dyeing and recombination, in particular to a graph dyeing and recombination method of an addressable DNA polyhedron topology. Background technique [0002] DNA nanotechnology refers to a method of using DNA as a synthetic material to design and construct complex structures and precisely control their nanometer properties. Its purpose is to use DNA chains as raw materials to synthesize three-dimensional or two-dimensional nanostructures. The reason DNA is suitable for creating nanoscale structures is that the binding between nucleic acid strands follows the known simple rules of base pairing, resulting in unique double-helical nanostructures. Taking advantage of this property, the assembly of structures can be easily controlled by the design of nucleic acid strands. [0003] Due to the special nature of DNA's own complementary base pairing, DNA nanostructures can exhibit good addressabilit...

Claims

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Application Information

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IPC IPC(8): G16C60/00
CPCG16C60/00
Inventor 段金伟王莹马蕾崔林
Owner CHANGAN UNIV
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