43results about How to "Convenient qualitative analysis" patented technology

The invention discloses a method for rapidly screening active ingredients of drugs based on an ultrafiltration-liquid chromatography-mass spectrometry. The method comprises the steps of dissolving a small molecular mixture of traditional Chinese medicine extract or other sources in a buffer solution, and adding enzyme for co-incubation; filtering the solution by ultracentrifugation concentration,repeating the filtering for multiple times, merging concentrated solutions, and making up the volume by the buffer solution; and analyzing the change of a chromatographic peak after the co-incubationof the enzyme by adopting a liquid chromatography-mass spectrometry technology. The method disclosed by the invention has the advantages that the hypoglycemic activity ingredients of the traditional Chinese medicines are screened by virtue of the ultrafiltration-UPLC-MS; and an experiment result shows that the method can carry out preliminary rapid screening on active small molecule compounds of anatural source in the complex ingredients. The method has the characteristics of simple operation, rapid batch screening, good experiment repeatability, visual and reliable experiment data and the like; and a new idea and method is provided for pharmacodynamic material basis research of the traditional Chinese medicines or the compounds.

The invention discloses a method of enhancing network capacity, comprising five procedures: A. a line between two nodes which have no connections is added, the sum of Betweenness of the whole network and standard deviation of Betweenness of the whole network are counted; B. the procedure A is repeatedly carried out, with every mode of adding a line between two nodes which have no connections, the sum of Betweenness of the whole network and standard deviation of Betweenness of the whole network are respectively counted; C. whether a line-adding mode exists is judged, if exists, then a procedure D is carried out and the procedure is over; if not exists, then a procedure E is carried out; D. a line is added in the network according to the line-adding mode which has the smallest standard deviation of the Betweeness of the whole network and the sum of Betweenness of the whole network; E. a line is added in the network according to a line-adding mode which has huge practical network capacity. The invention has the advantages of enhancing network capacity, avoiding unnecessary network equipment upgrade and reducing cost of enhancing network capacity.

The invention relates to an atmospheric pressure photoionization mass spectrum device for analyzing solid fuel pyrolysis on line. The device comprises a pyrolyzing furnace, an auxiliary volatile solvent introduction mechanism, an atmospheric pressure photoionization source and a mass spectrometer. With the increasingly exhausted fossil fuel, a process of preparing various hydrocarbon fuels and petrochemical materials through solid fuel pyrolysis is gradually concerned by people. According to the invention, the species distribution and generation mechanism of solid fuel pyrolysis products such as solid wastes (such as polypropylene), biomass, coal and oil shale can be accurately and rapidly analyzed on line in real time, people can be helped to well master the internal rules of pyrolysis, effective resource utilization is comprehensively realized, and the device has great significance on sustainable development of China.

The invention provides an underwater towing cable steady-state motion multi-objective optimization method and system, and the method comprises the steps: building a mathematic model of underwater towing cable motion, and calculating a towing cable steady-state motion control equation; selecting parameters for determining the state of the towing cable, selecting a sample point within the value range of the parameters, calculating the towing depth of the tail end and the tension of the head end of the towing cable to obtain the response of the sample point, and establishing a second-order polynomial response surface model of the towing depth of the tail end and the tension of the head end; and taking the maximum tail end dragging depth and the minimum head end tension as optimization objectives, and obtaining a Pareto optimal solution set of parameters by adopting a multi-objective genetic algorithm. Through the scheme, the problem that the influence degree of the parameters on the steady-state motion of the towing cable is difficult to accurately determine is solved, and the influence of each parameter on the towing cable state can be accurately analyzed.

The invention discloses an identification method for the effective components in a ginkgo leaf preparation. The identification method comprises: (1) preparing a testing product: taking a proper amount of a ginkgo leaf preparation to be detected, adding n-butanol, extracting, filtering, evaporating the filtrate, and adding ethanol to the residue to dissolve so as to be adopted as the testing product solution; (2) preparing a reference substance solution: taking a proper amount of a ginkgo leaf reference preparation, and preparing the reference substance solution according to the step (1); and (3) carrying out thin layer chromatography: respectively sucking 1-10 [mu]lt of the testing product solution and the reference substance solution, respectively spotting on the same silica gel G plate, developing with an ethyl acetate, isopropyl alcohol, methanol and water mixture, taking out the thin plate, carrying out air drying, spraying a 1-5% aluminum chloride ethanol solution, placing in a 365 nm ultraviolet light lamp, viewing the fluorescence, and observing the spot. According to the present invention, with the identification method, the good separation effects of various effective components are good, the spots are clear, the Rf value is moderate, various effective components can be accurately identified, and the qualitative analysis and quality control are easily achieved.

The invention discloses preparation of a three-dimensional SiO2-Ag porous structure and application of the three-dimensional SiO2-Ag porous structure in detection of volatile organic compounds. The preparation method comprises the following steps: firstly, preparing a SiO2 gas adsorption carrier with high specific surface area and high porosity through an acid-base two-step catalysis method, and then doping silver nanoparticles with a certain size into silicon dioxide to prepare the three-dimensional SiO2-Ag porous structure material. The structure has a large surface area; the porosity is high; high-concentration silicon hydroxyl (Si-OH) on the surface is realized; under the dual effects of physical adsorption and chemical bonding, the substrate has good gas adsorption and capture effects, can be used as a substrate material for enhancing Raman spectra for detection of volatile organic compounds, has excellent signal reproducibility and good stability, and has great application potential in field detection.

The invention provides a Blue Dream white liquor aroma component concentrating method. Blue Dream white liquor is measured and is added into a container, then a saturated salt solution is added, mixing is performed to obtain a solution to be extracted, wherein the volume ratio of the Blue Dream white liquor to the salt solution is 1:3-7; a mixed solution of dichloromethane, diethyl ether and hexane is added into the solution to be extracted, continuous extraction is performed to obtain an upper-layer organic phase, moisture in the organic phase is removed, and then filtration is performed by adopting a filter membrane; the mixed solution obtained after filtration by adopting the filter membrane is added into an impalement type fractionation device, the fractionation device is put into a constant-temperature water bath kettle of 45-55 DEG C to perform impalement type fractionation and concentration, and the mixed solution subjected to impalement type fractionation and concentration is concentrated by using a pressure blowing concentrator to obtain a Blue Dream white liquor aroma component. The Blue Dream white liquor aroma component concentrating method is simple and convenient to operate, capable of saving time and effort and low in cost, can play enrichment and concentration roles on minor components, facilitates qualitative and quantitative analysis on extremely trace amounts of substance, meanwhile effectively reduces loss of volatile components and improves the recovery rate of aroma substance.

The invention relates to a probe for efficiently detecting mercury ions and a preparation method and application thereof. Specifically, the probe provided by the invention is a fluorescent probe basedon coumarin compounds as fluorophores and mercaptan as a recognition receptor, can realize high-selectivity and ultra-sensitive analysis of mercury ions, and can determine the concentration of mercury ions in a sample. The probe can realize at least one of the following technical effects: high selectivity, strong anti-interference capability, quick response, convenient qualitative analysis, strong anti-interference capability, high sensitivity and wide detection range.

The invention discloses a method for rapidly detecting a compound with an instable structure and belongs to the technical field of analysis chemistry, solving the problem that the existing method can not accurately and rapidly detect the compound with the instable structure. The method comprises the following steps of: accurately weighing 10 mu L of compound with the instable structure on a screen, naturally drying the compound in the air; and placing the compound between a real-time direct analysis mass spectrometer ion source gas outlet and a linear ion trap mass spectrometer ion inlet, wherein when the ion source is in a positive or negative ion mode, the spray point voltage is 3kV, the grid voltage is 250 to 500V, the working gas is high-purity argon, the temperature is 200 to 500 DEG C and the pressure is 0.3 to 0.8MPa, and when the mass spectrometer is in a positive or negative ion mode, the capillary voltage is respectively 10 to 50V and 10 to 50V below zero, the lens voltage is respectively 50 to 150V and 50 to 150V below zero, the capillary temperature is 250 to 300 DEGC, and the mass-to-charge ratio in a scanning range is 60 to 700Da. The method is accurate, quick and high in sensitivity.

The invention relates to a method for qualitatively measuring nonionic surfactants of a compounded system. According to the method, a C18 adsorbent and 11 eluents with gradually enhanced elution capabilities are adopted, researches on 11 eluates of 5 nonionic surfactants with similar structures, polarities and molecular weights are made by virtue of simple methods of pH test paper, visual measurement, infrared spectrums and the like, pH values, elution amounts and principal component parameters of the 11 eluates of each surfactant form a group of data with strong characteristics, and the nonionic surfactants in the compounded system can be qualitatively analyzed conveniently according to the data of the surfactants. The qualitative method is convenient, no time is required to be consumed in exploring and selecting various chromatographic separation conditions, and the qualitative analysis efficiency is greatly improved; such a concept can not only be used for qualitative analysis overthe compounded system with the 5 surfactants but also be suitable for qualitative analysis over nonionic surfactants in other compounded systems.