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Oil-control anti-inflammatory plant combined extract and preparation method and application thereof

A technology of extracts and plants, which is applied in the field of oil control and anti-inflammatory plant combination extracts and its preparation, can solve the problems of unsatisfactory oil control and anti-inflammation effects, air permeability and pro- Poor skin and other problems, to achieve long-term oil control effect, the oil control time is not easy to repeat, and the oil control time is long

Active Publication Date: 2021-03-30
山东花物堂生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Currently, existing oil-controlling skin care products on the market often use oil-absorbing powders (such as silicon dioxide, titanium dioxide, talc, etc.) or plant extracts as oil-controlling active ingredients. The former uses powder particles to quickly fill pores and absorb excess oil. This can improve the problem of oily skin. However, the use of oil-absorbing powder can only temporarily reduce the skin’s shine, and it cannot treat both symptoms and root causes, and even excessive addition may cause problems such as pore clogging; and currently commonly used oil-controlling plant extracts, such as witch hazel Plum, calendula, aloe, viola, etc. have less side effects, but there are also problems such as slow effect, short effective time, easy to repeat, etc. The oil control and anti-inflammatory effect is not ideal
[0006] Patent CN110538088A provides a skin care composition. The skin care composition is aimed at the problem that the functional ingredients of acids or proteases with strong hydrophilicity can only act on the surface of the skin, but the effect of penetrating into the hair follicle is weak, so the oil control effect is poor. A pure oil skin care product
However, this skin care composition is prepared by mixing multiple functional ingredients, which does not have the naturalness and broader-spectrum efficacy of plant extracts, and the air permeability and skin affinity of lipophilic skin care products are worse than those of hydrophilic functional ingredients. , which is not conducive to improving the user experience

Method used

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  • Oil-control anti-inflammatory plant combined extract and preparation method and application thereof
  • Oil-control anti-inflammatory plant combined extract and preparation method and application thereof
  • Oil-control anti-inflammatory plant combined extract and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0078] This example provides a plant composition extract for oil control and anti-inflammation, which is prepared by the following method:

[0079] Step (1): Weigh 40g of olive leaves, 30g of gallbladder and 20g of Ligustrum privet respectively, after the above-mentioned raw materials are crushed into 100 mesh at high speed, sieved, and mixed evenly to obtain a mixed powder; mix the mixed powder with a volume concentration of 70% The ethanol solution is mixed according to the ratio of solid-liquid ratio of 1g: 10ml, and extracted twice, wherein the first extraction is extracted by heating and reflux for 3h, the filtrate and the filter residue are separated by filtration, and the filter residue and the ethanol solution with a volume concentration of 70% The second extraction is carried out by mixing according to the ratio of solid-liquid ratio of 1g: 10ml. The second extraction is extracted by heating and reflux for 1 hour, filtered, and the filtrates obtained by the two extract...

Embodiment 2

[0085] This example provides a plant composition extract for oil control and anti-inflammation, which is prepared by the following method:

[0086] Step (1): Weigh 30g of olive leaves, 25g of gallbladder green leaves and 25g of privet fruit respectively, after the above-mentioned raw materials are crushed into 100 meshes at high speed, sieve, and mix uniformly to obtain a mixed powder; mix the mixed powder with a volume concentration of 70% The ethanol solution is mixed according to the ratio of solid-liquid ratio of 1g: 10ml, and extracted twice, wherein the first extraction is extracted by heating and reflux for 3h, the filtrate and the filter residue are separated by filtration, and the filter residue and the ethanol solution with a volume concentration of 70% The second extraction is carried out by mixing according to the ratio of solid-liquid ratio of 1g: 10ml. The second extraction is extracted by heating and reflux for 1 hour, filtered, and the filtrates obtained by the ...

Embodiment 3

[0092] This example provides a plant composition extract for oil control and anti-inflammation, which is prepared by the following method:

[0093] Step (1): Weigh 25g of olive leaves, 20g of gallbladder and 40g of Ligustrum privet respectively, after the above-mentioned raw materials are crushed into 100 mesh at high speed, sieved, and mixed uniformly to obtain a mixed powder; mix the mixed powder with a volume concentration of 80% The ethanol solution is mixed according to the ratio of solid-liquid ratio of 1g: 10ml, and extracted twice, wherein the first extraction adopts heating and reflux extraction for 3h, and the filtrate and the filter residue are separated by filtration, and the filter residue and the ethanol solution with a volume concentration of 80% The second extraction is carried out by mixing according to the ratio of solid-liquid ratio of 1g: 10ml. The second extraction is extracted by heating and reflux for 1 hour, filtered, and the filtrates obtained by the tw...

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Abstract

The invention provides an oil-control anti-inflammatory plant combined extract. The plant combined extract is prepared from the following raw materials in parts by mass: 15-45 parts of olive leaves, 15-45 parts of swertia pseudochinensis, 15-45 parts of ligustrum lucidum fruits, 4-25 parts of coptis chinensis, 4-25 parts of angelica sinensis and 4-25 parts of liquorice. The invention further provides a preparation method and application of the plant combined extract. According to the plant combined extract, component raw materials of specific types and dosage ratios are mixed and extracted, and when the obtained product is applied to skin care products, the instant oil control effect and the long-acting oil control effect are obviously improved, oil control takes effect quickly and is notprone to relapse, and compared with common oil control plant extracts, the plant combined extract has the remarkable oil control advantage; moreover, I-type 5 alpha-reductase and II-type 5 alpha-reductase can be effectively inhibited, IL-1beta, TNF-alpha and COX-2 inflammatory factors which are over-expressed due to breeding of anaerobic bacteria acnes in skin hair follicles are inhibited, and theeffect of treating both symptoms and root causes is achieved.

Description

technical field [0001] This application relates to the technical field of fine chemical daily necessities, in particular to a plant combination extract for oil control and anti-inflammation, its preparation method and application. Background technique [0002] Oily skin is caused by exuberant secretion of sebaceous glands and dysfunction of sebaceous glands. The sebaceous gland is an important gland attached to the skin and is an important part of sebum production. For people with oily skin, the sebaceous glands secrete more oil than normal. Excessive oil will make the skin surface shiny and easy to be contaminated with pollutants in the environment. At the same time, it is also prone to some corresponding skin diseases, such as skin sensitivity and allergies, acne and seborrheia Sexual dermatitis, etc., can also cause seborrheic alopecia and so on. Scientific research has found that the causes of sebaceous gland dysfunction are complex, and the lesions formed are also div...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/34A61Q19/00A61Q17/00A61Q7/00A61K36/718A61K47/10A61P29/00A61P17/18A61P17/10A61P17/14
CPCA61K8/9789A61K8/345A61Q19/008A61Q17/005A61Q19/00A61Q7/00A61K36/63A61K36/51A61K36/638A61K36/718A61K36/232A61K36/484A61K47/10A61P29/00A61P17/18A61P17/10A61P17/14A61K2800/782A61K2800/5922A61K2800/592A61K2236/331A61K2236/53A61K2236/333A61K2236/39A61K2236/51A61K2300/00Y02A50/30
Inventor 亓云吉
Owner 山东花物堂生物科技有限公司
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