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Traditional Chinese medicine composition for preventing and controlling novel coronavirus pneumonia, preparation, preparation method and application

A technology of traditional Chinese medicine preparations and compositions, applied in the field of traditional Chinese medicine compositions for the prevention and control of new coronary pneumonia, can solve the problems of inconvenient transfer of Indigo Naturalis, increased impurity content of leachate, and incomplete separation of leachate and Indigo Naturalis.

Pending Publication Date: 2021-04-09
成都晶博生物科技有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] During the diafiltration process of Indigo Naturalis in production and preparation, incomplete separation of leachate and Indigo Naturalis often occurs, which increases the impurity content in the leachate, and at the same time it is inconvenient to transfer the indigo naturalis that has been diafiltered from the infiltration tank, increasing the Indigo Naturalis is difficult to infiltrate, reducing production

Method used

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  • Traditional Chinese medicine composition for preventing and controlling novel coronavirus pneumonia, preparation, preparation method and application
  • Traditional Chinese medicine composition for preventing and controlling novel coronavirus pneumonia, preparation, preparation method and application
  • Traditional Chinese medicine composition for preventing and controlling novel coronavirus pneumonia, preparation, preparation method and application

Examples

Experimental program
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Effect test

Embodiment 1

[0089] Such as Figure 1-Figure 3 According to the following weight proportions, take the six-flavored Chinese herbal medicines respectively: 800g of Sanyinhua, 350g of Trichosanthes peel, 30g of Qingdai, 4g of bear bile powder, 450g of Platycodon grandiflorum, and 150g of licorice, and then according to the following formula: figure 1 The capsule preparation process shown is prepared:

[0090] (1) Take Indigo Naturalis, use 5 times the amount of 60% ethanol as a solvent, and use the Indigo Naturalis percolation device, soak for 18 hours and then percolate, collect the leachate, and use the dregs for later use;

[0091] (2) Take mountain silver for redistillation, soak mountain silver flower with 6 times drinking water for 0.3h, heat and boil and keep slightly boiling to realize redistillation; collect 200ml of aromatic water; filter the medicinal liquid in the tank with 50 mesh to obtain The distilled aqueous solution is stored in another container, and the medicinal residue...

Embodiment 2

[0098]Weigh the six flavors of Chinese herbal medicines according to the following weight proportions: 900g of Sanyinhua, 450g of Trichosanthes peel, 80g of Qingdai, 6g of bear bile powder, 550g of Platycodon grandiflorum, and 250g of licorice, and then figure 2 The procedure shown for capsule preparation:

[0099] (1) Take Indigo Naturalis, use 5 times the amount of 90% ethanol as a solvent, and use the Indigo Naturalis percolation device, soak for 36 hours and then percolate, collect the leachate, and use the dregs for later use;

[0100] (2) Take mountain silver for redistillation, soak mountain silver flower with 10 times drinking water for 1 hour, heat and boil and keep slightly boiling to realize redistillation; collect 300ml of aromatic water; filter the medicinal liquid in the tank with 100 mesh to obtain distillation The final aqueous solution is stored in another container, and the medicinal residues are used for subsequent use;

[0101] (3) Soak Platycodon grandif...

Embodiment 3

[0107] Weigh the six flavors of Chinese herbal medicines according to the following weight proportions: 850g of Sanyinhua, 400g of Trichosanthes bark, 50g of Qingdai, 5g of bear bile powder, 500g of Platycodon grandiflorum, 200g of licorice, and then follow the steps as follows: image 3 The process shown for oral solution preparation:

[0108] (1) Take Indigo Naturalis, use 5 times the amount of 80% ethanol as a solvent, and use the Indigo Naturalis infiltration device, soak for 24 hours, then infiltrate, collect the leachate, and use the dregs for later use;

[0109] (2) Take mountain silver for redistillation, soak mountain silver flower with 8 times of drinking water for 0.5h, heat and boil and keep slightly boiling to realize redistillation; collect 250ml of aromatic water; filter the medicinal liquid in the tank with 200 mesh to obtain The distilled aqueous solution is stored in another container, and the medicinal residue is used for subsequent use;

[0110] (3) Soak P...

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Abstract

The invention discloses a traditional Chinese medicine composition for preventing and controlling novel coronavirus pneumonia, a preparation, a preparation method and application. The traditional Chinese medicine composition is prepared from the following raw materials in weight ratio: 850g of flos lonicerae, 400g of trichosanthes peel, 50g of indigo naturalis, 5g of bear gall powder, 500g of platycodon grandiflorum and 200g of radix glycyrrhizae, 1000ml of the preparation is prepared, the preparation is orally taken, is taken 10ml each time and is taken 3-4 times a day, and the dosage of the preparation is increased for severe cases, is reduced for children or follows doctor's orders. Animal experiments show that the preparation is wide in application, has a remarkable antipyretic effect on rabbit fever caused by typhoid fever and paratyphoid fever vaccine, and has a certain antipyretic effect on rat fever caused by carrageenan; acute inflammation with exudation and edema as main symptoms is inhibited through multiple ways; and immunity is enhanced, and growth and propagation of part of pathogenic microorganisms are inhibited. Clinical tests show that the traditional Chinese medicine composition is relatively good in fever abatement effect, the average cooling time is obviously shorter than that of a Yinhuang oral liquid group, and the traditional Chinese medicine composition has the effects of clearing away heat and toxic materials, ventilating the lungs, relieving exterior syndromes, relieving sore throat and reducing phlegm, can be used for treating accumulation of pathogenic heat in the lung caused by novel coronavirus and is free of toxic and side effects.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition, preparation, preparation method and application for the prevention and control of COVID-19. Background technique [0002] Novel coronavirus pneumonia is mainly manifested by fever, dry cough, fatigue, etc., and a small number of patients are accompanied by upper respiratory tract and digestive tract symptoms such as nasal congestion, runny nose, and diarrhea. In the field of traditional Chinese medicine, fever, runny nose, stuffy nose, cough, expectoration, headache, general malaise, sweating, thirsty mouth, poor spirits, etc. can be summarized as the syndrome of pathogenic heat obstructing the lung. The syndrome of pathogenic heat obstructing the lungs refers to the clinical manifestations of exogenous evils invading the lungs, stagnation and heat transformation, heat injury to the lungs and fluid, phlegm formed by...

Claims

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Application Information

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IPC IPC(8): A61K36/704A61K36/484A61P31/14A61P11/00A61K35/413
CPCA61K36/355A61K36/428A61K36/704A61K36/315A61K36/195A61K35/413A61K36/346A61K36/484A61P31/14A61P11/00A61K2236/333A61K2236/331A61K2236/53A61K2236/51A61K2236/39A61K2300/00Y02A50/30
Inventor 王芹胡义新
Owner 成都晶博生物科技有限责任公司
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