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A kind of Lactobacillus rhamnosus lr863 and Lactobacillus rhamnosus lr519 that synergistically inhibit Helicobacter pylori and their application

A technology of Lactobacillus rhamnosus and LR863, applied in the field of microorganisms, can solve the problem of single inhibitory effect of Helicobacter pylori, etc., and achieve the effects of improving the vitality of gastric mucosa, improving the inhibitory effect, and inhibiting gastric acid.

Active Publication Date: 2022-07-29
河北一然生物科技股份有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The present invention proposes a kind of Lactobacillus rhamnosus LR863 and Lactobacillus rhamnosus LR519 that synergistically inhibit Helicobacter pylori and their application, which solves the problem that the inhibitory effect of the Helicobacter pylori inhibiting composition on Helicobacter pylori in the prior art is relatively single The problem

Method used

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  • A kind of Lactobacillus rhamnosus lr863 and Lactobacillus rhamnosus lr519 that synergistically inhibit Helicobacter pylori and their application
  • A kind of Lactobacillus rhamnosus lr863 and Lactobacillus rhamnosus lr519 that synergistically inhibit Helicobacter pylori and their application
  • A kind of Lactobacillus rhamnosus lr863 and Lactobacillus rhamnosus lr519 that synergistically inhibit Helicobacter pylori and their application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A mixed probiotic for inhibiting Helicobacter pylori, comprising Lactobacillus rhamnosus LR863 and Lactobacillus rhamnosus LR519 in a mass ratio of 1:1.

Embodiment 2

[0035] A mixed probiotic for inhibiting Helicobacter pylori, comprising Lactobacillus rhamnosus LR863 and Lactobacillus rhamnosus LR519 in a mass ratio of 3:2.

Embodiment 3

[0037] A mixed probiotic for inhibiting Helicobacter pylori, comprising Lactobacillus rhamnosus LR863 and Lactobacillus rhamnosus LR519 in a mass ratio of 2:1.

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PUM

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Abstract

The invention belongs to the technical field of microorganisms, and provides Lactobacillus rhamnosus LR863 and Lactobacillus rhamnosus LR519 that synergistically inhibit Helicobacter pylori and applications thereof, including Lactobacillus rhamnosus LR863 and Lactobacillus rhamnosus LR519. Mixed probiotics are used to prepare food that inhibits Helicobacter pylori in the oral cavity and stomach and improves intestinal tract. The food includes component A and component B, and component A is Lactobacillus rhamnosus with a mass ratio of 1-2:1 Mixed probiotics composed of LR863 and Lactobacillus rhamnosus LR519, component B includes the following components by weight: 15 parts of Hericium erinaceus powder, 3 parts of galactooligosaccharide, 15 parts of Poria powder, 10 parts of Spirulina, Seabuckthorn 20 servings of powder also include component C, wherein component C is one or more of Bifidobacterium, Lactobacillus acidophilus, and Lactobacillus plantarum. The above technical solution solves the problem that the composition for inhibiting Helicobacter pylori in the prior art has a relatively single inhibitory effect on Helicobacter pylori.

Description

technical field [0001] The invention belongs to the technical field of microorganisms, and relates to Lactobacillus rhamnosus LR863 and Lactobacillus rhamnosus LR519 that synergistically inhibit Helicobacter pylori and applications thereof. Background technique [0002] Helicobacter pylori (Hp) is a helical, unipolar, polyflagellated, Gram-negative, microaerophilic bacterium that colonizes the stomach and duodenum. The presence of Helicobacter pylori was also detected in the oral cavity and feces. Hp is closely related to a variety of digestive system diseases. Hp infection is an important cause of many digestive tract diseases such as chronic gastritis, peptic ulcer and gastric cancer. The World Health Organization has listed Hp as a class I carcinogen. [0003] Human itself is a complex living body, and there are a large number of microbial communities with complex structures on the body surface and the mucous membranes in the body. With the deepening of Hp research, Hel...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12N1/20A23L33/135A23L33/10A23L33/125A23L19/00A23L31/00C12R1/225
CPCC12N1/20A23L33/135A23L33/10A23L33/125A23L19/01A23L31/00A23V2002/00A23V2400/113A23V2400/175A23V2400/169A23V2400/51A23V2200/32A23V2200/3204A23V2250/28
Inventor 赵林森高景伟路江浩张士成刘明月贾晓蒙杨玲孙新凯孙策
Owner 河北一然生物科技股份有限公司
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