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A kind of oral care composition containing probiotics and its application

A technology for oral care and composition, applied in the field of daily chemicals, can solve the problems of yellowing of toothpaste, increase product instability, weak antibacterial activity, etc., and achieves improvement of inhibitory ability, avoidance of paste quality decline, and good curative effect. Effect

Active Publication Date: 2022-03-25
江苏新申奥生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, probiotics still have the following defects as biological antibacterial agents: ①The antibacterial activity is weaker than that of chemical antibacterial agents, and a large amount of addition is often required to ensure its antibacterial effect, which increases the instability of the product; Metabolites can easily cause yellowing of toothpaste paste

Method used

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  • A kind of oral care composition containing probiotics and its application
  • A kind of oral care composition containing probiotics and its application
  • A kind of oral care composition containing probiotics and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment 1, the preparation of microcapsule

[0031] S1. Dissolving shellac resin in an aqueous sodium carbonate solution with a concentration of 0.1mol / L at 65°C to prepare a saturated shellac resin sodium salt solution, freeze-drying, and grinding to obtain shellac resin sodium salt for later use;

[0032] S2, dissolving carboxymethyl chitosan in water to prepare an aqueous carboxymethyl chitosan solution with a concentration of 0.5 mg / mL; dissolving shellac resin sodium salt in water to prepare a concentration of 3 mg / mL sodium shellac resin Saline solution; the above-mentioned carboxymethyl chitosan aqueous solution and shellac resin sodium salt aqueous solution were mixed, and at room temperature, magnetically stirred for 12 minutes to obtain a shellac resin sodium salt-chitosan complex; the carboxymethyl chitosan and The mass ratio of lac resin sodium salt is 0.22:1;

[0033] S3. Weigh the lac resin sodium salt-chitosan complex, dissolve it in water, add probi...

Embodiment 2

[0035] Embodiment 2, the preparation of microcapsule

[0036] S1. Dissolving the shellac resin in an aqueous solution of sodium carbonate with a concentration of 0.2 mol / L at 60° C. to prepare a saturated sodium shellac resin solution, freeze-drying, and grinding to obtain the sodium shellac resin for later use;

[0037] S2, dissolving carboxymethyl chitosan in water to prepare an aqueous carboxymethyl chitosan solution with a concentration of 0.1 mg / mL; dissolving shellac resin sodium salt in water to prepare a concentration of 1 mg / mL sodium shellac resin Saline solution; the above-mentioned carboxymethyl chitosan aqueous solution and shellac resin sodium salt aqueous solution were mixed, and at room temperature, magnetically stirred for 10 minutes to obtain a shellac resin sodium salt-chitosan complex; the carboxymethyl chitosan and The mass ratio of lac resin sodium salt is 0.1:1;

[0038] S3. Weigh the lac resin sodium salt-chitosan complex, dissolve it in water, add p...

Embodiment 3

[0040] Embodiment 3, the preparation of microcapsule

[0041] S1. Dissolving the shellac resin in an aqueous solution of sodium carbonate with a concentration of 0.3 mol / L at 60° C. to prepare a saturated sodium shellac resin salt solution, freeze-drying, and grinding to obtain the shellac resin sodium salt for later use;

[0042] S2, dissolving carboxymethyl chitosan in water to prepare an aqueous carboxymethyl chitosan solution with a concentration of 1 mg / mL; dissolving shellac resin sodium salt in water to prepare a concentration of 3 mg / mL shellac resin sodium salt aqueous solution; the above-mentioned carboxymethyl chitosan aqueous solution and lac resin sodium salt aqueous solution were mixed, and at room temperature, magnetically stirred for 10 minutes to obtain a shellac resin sodium salt-chitosan complex; the carboxymethyl chitosan and violet The mass ratio of gum resin sodium salt is 0.35:1;

[0043] S3. Weigh the lac resin sodium salt-chitosan complex, dissolve it...

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Abstract

The invention belongs to the technical field of daily chemicals, and in particular relates to an oral care composition containing probiotics and an application thereof. The toothpaste provided by the invention is added with various probiotics capable of inhibiting oral pathogenic bacteria, which can secrete various antibacterial substances, maintain the micro-ecological balance in the oral cavity, and have good curative effect on gingivitis and halitosis.

Description

technical field [0001] The invention belongs to the technical field of daily chemicals. More specifically, it relates to an oral care composition containing probiotics and a preparation method thereof. Background technique [0002] The human oral cavity is a complete ecosystem, in which a variety of microorganisms such as bacteria, fungi, mycoplasma, protozoa and viruses are colonized. In the oral cavity, the oral cavity can only maintain a healthy state if a good ecological balance is maintained between the microorganisms and the oral tissue of the host. If the proportion increases, the original oral ecological balance will be broken, and flora imbalance will appear. Therefore, the oral micro-ecological balance has a very close relationship with the health and diseases of the oral cavity. For example, the occurrence of dental caries is mainly related to the significant increase in the proportion of bacteria on the enamel surface of Streptococcus mutans or Streptococcus ma...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/99A61K8/73A61K8/11A61Q11/00A61P31/04A61P1/02
CPCA61K8/99A61K8/11A61K8/736A61K8/73A61Q11/00A61P31/04A61P1/02A61K2800/84A61K2800/5922
Inventor 钟达金
Owner 江苏新申奥生物科技有限公司
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