Brain function network evolution modeling method for sensorineural deafness

A technology of brain function network and modeling method, which is applied in the field of portable sharps box, can solve the problem that it is impossible to quantitatively evaluate the brain auditory network function of patients with sensorineural deafness and predict the direction of later disease progression.

Pending Publication Date: 2021-05-25
XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV
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Problems solved by technology

[0004] The purpose of the present invention is to provide a brain function network evolution modeling method for sensorineural deafness, so as to solve the problem that in the prior art, with the progress of deafness disease, i

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  • Brain function network evolution modeling method for sensorineural deafness
  • Brain function network evolution modeling method for sensorineural deafness

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[0027] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0028] Such as figure 1 As shown, the present invention provides a brain function network evolution modeling method for sensorineural deafness. Based on the dynamic characteristics of the whole brain brain region network, the state observation of the whole brain brain region at a single time sampling point is constructed. matrix, and then obtain its state set through unsupervised clustering. On this basis, the automata theory is used to establish a time model ...

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Abstract

The invention discloses a sensorineural deafness brain function network evolution modeling method, which comprises the following steps: S01, extracting brain network state data, taking a BOLD signal of a resting state fMRI as an object, analyzing and extracting the state expression of a brain network through a sliding window technology, and obtaining the high-dimensional vector expression of the brain network state; s02, acquiring a low-dimensional mapping and clustering result by using the state observation matrix; s03, analyzing a conversion mode of the brain network state, constructing a state set according to a clustering result of the state, analyzing a relationship between state switching and time, and obtaining a time sequence diagram of brain network state evolution on a time axis; s04, on the basis of the brain network evolution model of the timed automaton, according to the brain network state evolution sequence diagram, establishing an evolution process model through the timed automaton theory, a quantitative brain network dynamic description model is provided, and the state transition rule and the evolution process of the human brain network can be effectively described. The method has universality for different tested data, and abnormal evolution process of the subject can be identified.

Description

technical field [0001] The embodiment of the present invention relates to the field of medical equipment, in particular to a portable sharps box. Background technique [0002] Deafness is one of the common diseases that seriously affects human health and life. The incidence rate in adults accounts for nearly 10%, and with the increase of age, the incidence rate of deafness shows a clear upward trend. The perception of sound depends on a series of complex structures. This series of structures includes not only the collection and transmission of sound by the ear, but also the transmission and analysis of the corresponding auditory nerve and auditory nerve center. [0003] At present, although the research on the brain function network of sensorineural deafness has achieved certain results, there are still several problems that need to be solved urgently. First, as the disease progresses, the brain function of patients with sensorineural deafness is still unclear. How to evolv...

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Application Information

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IPC IPC(8): A61B5/12
CPCA61B5/121A61B5/4842A61B5/7246
Inventor 范文亮杨帆郑传胜刘定西孔祥闯刘小明
Owner XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV
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