Enhanced nitrate compositions and methods of use

Abstract

The disclosure is directed to methods of reducing blood pressure, treating hypertension, improving athletic performance, and increasing aerobic capacity, stamina, muscle strength, endurance, and / or time to exhaustion in a subject comprising co-administering to the subject elemental metal and a source of nitrate anion (NO<3->). The disclosure is also directed to related compositions comprising elemental metal and a source of nitrate anion (NO<3->).

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit and priority of U.S. Provisional Patent Application 62 / 800,361, filed February 1, 2019, and U.S. Provisional Patent Application 62 / 866,540, filed June 25, 2019, the entire disclosures of which are herein Incorporated by reference. Background technique [0003] Applicants found in 2007 that application of nitrates (NO 3 - , also described herein as the nitrate anion) can enhance athletic performance, increase blood flow, and improve vasodilation. Since Applicant's discovery, the research community has discovered many benefits of these inorganic nitrates, such as improved exercise fatigue, increased time to failure, reduced oxygen consumption during exercise, reduced susceptibility to metabolic stress-related diseases Oxygen consumption, improved glucose metabolism disturbances, decreased body fat percentage (thus helping to reduce the likelihood of developing obesity and pre-obesity)...

AI Technical Summary

Problems solved by technology

This could draw the attention of regulators, raising safety concerns and prohibiting the marketing of nitrate products in appropriate doses

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