Extracorporeal circulation experiment table and experiment method for thrombus formation of medical implant interventional body
A kind of extracorporeal circulation and experimental bench technology, which is applied in the direction of fluid dynamics test, testing of machine/structural components, instruments, etc. It can solve the problem of inability to effectively guide the optimization of anticoagulation and thrombosis suppression design, inability to simulate thrombosis, and thrombosis dependent on animal experiments. And other issues
Active Publication Date: 2021-10-15
TSINGHUA UNIV
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Problems solved by technology
However, due to the limitations of experimental time and test methods, the existing test benches cannot simulate the formation of thrombus in vivo medical implants in vitro experiments. The observation of thrombus can only rely on animal experiments, which cannot quickly, conveniently and effectively guide implants. Design optimization of anticoagulant and antithrombotic into medical devices
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[0042] Embodiments of the present invention are described in detail below, examples of which are shown in the drawings, wherein the same or similar reference numerals designate the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by referring to the figures are exemplary only for explaining the present invention and should not be construed as limiting the present invention.
[0043] Combine below figure 1 An extracorporeal circulation test bench 1000 for embolization of medical implants according to an embodiment of the present invention is described.
[0044] Such as figure 1 As shown, the extracorporeal circulation test bench 1000 for embolization of medical implants according to the embodiment of the first aspect of the present invention includes an experimental section module 1, a circulation loop module 2 and a temperature control module 3, wherein the experimental section module 1 includes a driving fo...
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The invention discloses an extracorporeal circulation experiment table and an experiment method for thrombus formation of a medical implant interventional body. The experiment table comprises an experiment section module, a circulation loop module and a temperature control module, wherein the experiment section module comprises a medical implant intervention body with a power pump and a transparent tube with biocompatibility, the medical implant intervention body is arranged in the transparent tube, and the transparent tube is provided with an inlet end and an outlet end; the circulation loop module and the experiment section module jointly form a circulation loop used for circulating flowing of experiment liquid. The circulation loop module is used for monitoring and controlling the pressure and flow of the experimental liquid flowing circularly in a circulation loop; and the temperature control module is used for controlling the temperature of the experimental liquid in the circulation loop. According to the experiment table, the environment in the human body can be well simulated, the growth condition of thrombus in the body can be simulated within controllable time, and a stable and reliable experimental platform is provided for the research on the anticoagulation and thrombus inhibition performance of implanted medical devices.
Description
technical field [0001] The invention relates to the technical field of experimental testing equipment for medical implants, in particular to an extracorporeal circulation test bench and an experimental method for embolization of medical implants. Background technique [0002] Cardiovascular disease seriously threatens human health and life. At present, medical implants are one of the most effective means of treating cardiovascular and cerebrovascular diseases. Common medical implants that are in direct contact with blood include artificial hearts, artificial heart valves, and artificial stents. All medical implants need to go through preclinical tests, including in vitro experiments on extracorporeal circulation test platforms, standard laboratory tests (such as biocompatibility tests of materials used, thermal noise tests, etc.) and animal experiments. Animal experiments are expensive and time-consuming, and there is a huge difference between standard experiments and actua...
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Login to View More IPC IPC(8): G01D21/00G01M10/00
CPCG01D21/00G01M10/00
Inventor 陈皓生李永健蒙奎霖郑晓冰
Owner TSINGHUA UNIV