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A high-precision liquid level detection system and method based on ripple image recognition

A liquid level detection and image recognition technology, applied in the field of biochemistry, can solve the problems of increasing equipment environment configuration requirements, limit of detectable liquid types, and low liquid level detection accuracy.

Active Publication Date: 2022-04-19
TSINGHUA UNIV
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  • Abstract
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  • Application Information

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Problems solved by technology

[0006] 1) The types of liquids that can be detected are limited, or additional experimental settings are required: most current detection technologies have requirements for the properties of the liquid to be tested, such as the resistance method that requires the liquid to conduct electricity; or the detection method is greatly affected by the properties of the liquid, such as the electromagnetic method Since the electromagnetic attenuation varies with the dielectric constant of the liquid, the measurement accuracy varies with the properties of the liquid, making it difficult to achieve universal measurement of common liquids in laboratories or industries
In addition, in order to realize the measurement, some techniques such as the capacitance method need to set an additional metal plate at the bottom of the container, which increases the equipment environment configuration requirements
[0007] 2) Low accuracy of liquid level detection: Most of the current existing technologies measure the liquid level at the μm level, and it is difficult to provide nm-level positioning accuracy to meet the requirements of micro-nano operation

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  • A high-precision liquid level detection system and method based on ripple image recognition

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Embodiment Construction

[0039] In order to illustrate the present invention more clearly, the present invention will be described in detail below in conjunction with the accompanying drawings and embodiments.

[0040] The invention provides a high-precision liquid level detection system based on corrugated image recognition, which is composed of a microscope, a micro-operation mobile platform, a holder, a micro-needle, a piezoelectric transducer and a driver, an image acquisition device, and a liquid to be tested. The schematic diagram of the system composition is as figure 1 As shown, the signal generator cascades the power amplifier to generate a sinusoidal voltage signal that can drive the periodic vibration of the PZT, and the microneedle generates stable periodic vibration under the fixation of the holder. At the same time, the micro-manipulation mobile platform controls the entire holder along the The direction perpendicular to the liquid surface touches the liquid surface, and the whole proce...

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Abstract

The invention discloses a high-precision liquid level detection system and method based on corrugated image recognition. A piezoelectric transducer (PZT) is used to make the end effector in the process of descending generate high-frequency vibrations. During the process, ripples are generated on the liquid surface, and image recognition technology is used to identify the generation of ripples at the moment of contact to realize the judgment of the point of contact between the needle tip of the end effector and the liquid surface. The key to realizing the contact positioning between the needle tip and the liquid surface is to generate identifiable ripples. As well as image recognition of ripples, the invention can be used in the field of fully automated micro-nano operating instruments that require accurate judgment of liquid levels, and has broad application prospects in occasions involving liquid sample processing such as drug distribution, food, beverage processing, and biochemical analysis.

Description

technical field [0001] The invention belongs to the technical field of biochemistry, and relates to liquid level detection instruments and methods for liquid samples, in particular to a high-precision liquid level detection system and method based on ripple image recognition. Background technique [0002] Traditional biochemical analysis instruments can quickly provide detection evidence for doctors and chemical testing personnel by detecting the liquid environment in the human body, such as blood, urine, and cell metabolism culture fluid, and play an important role in clinical diagnostic analysis and biochemical testing. In the biochemical monitoring and analysis system, it is necessary to extract the specific liquid to be tested and perform the operation of pipetting. A complete pipetting process includes operations such as extracting the pipette, liquid level detection, sucking the sample, transferring the pipette, and distributing the sample. The fully automated operatio...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01F23/00G06V20/20
CPCG01F23/003
Inventor 王文会梁非赵鹏
Owner TSINGHUA UNIV