High-oxygen-permeability corneal contact lens and preparation method thereof

A corneal contact lens and oxygen transmission rate technology, which are applied in the preparation of polysiloxane macromonomer cross-linking agent materials, the preparation of high oxygen transmission rate corneal contact lenses, and the surface hydrophilic modification of corneal contact lenses. , can solve the problems of low oxygen permeability, low water content of lenses, development and application limitations, etc., to achieve the effect of comfortable wearing and good wetting performance

Pending Publication Date: 2021-11-30
吉林爱惠瞳医用科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, lenses based on this type of material have low water content and are easy to adhere to the eyeball, affecting the safety and comfort of invisible wear
[0008] Based on the above analysis, the oxyg

Method used

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  • High-oxygen-permeability corneal contact lens and preparation method thereof
  • High-oxygen-permeability corneal contact lens and preparation method thereof
  • High-oxygen-permeability corneal contact lens and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0036] Example 1

[0037] This example discloses a hydrophilic segment modification, a double-bonded polydimethylsiloxane large monomer crosslinking agent, which includes the following steps:

[0038] 1. Add KF-6001 (7.5 g) into a 100 ml bump, insert mechanical stirring, cock coating vacuum, grouped with vacuum line, 55 ° C water bath, vacuum drying for 2 h.

[0039] 2. At the same time, KF-6002 (30g) is added to the single-mouth flask, the drying method is the same.

[0040]3300rpm under mechanical stirring, is added IPDI (1.67g), stirred at 55 ℃ until complete dissolution, with the injector suction micro 100ul of DBTDL (100ul) was added dropwise in the reactor (> 10min), the reaction 2h.

[0041] 4, using a syringe KF-6002 (24.8g) into the reactor, injector suction micro 100ul amount of DBTDL (100ul) was added dropwise in a reactor, reacted at 55 ℃ overnight.

[0042] 5, the pressure to atmospheric pressure balance 30min, weighing IEM (1.165g) by the amount of difference method,...

Example Embodiment

[0044] Example 2

[0045] In the present embodiment, on the basis of Example 1 discloses a method for preparing a silicone hydrogel material, comprising the steps of:

[0046] Amount of 41.7% in mass percentage in Example 1 polydimethylsiloxane macromer crosslinking agent, 22.6% by mass percentage of N'N- dimethylacrylamide (DMA), 15.9% of the mass percentage A yl acryloxy propyl tris (trimethylsiloxy) silane (Tris), 1.0% by mass percentage of Darocur 1173, was dissolved in n-propanol of 18.8% by mass percentage of diluent is magnetically stirred for 20 min, ultrasonic extinction soak for 10 minutes to the polymerization solution for use. With a pipette to draw the polymerization solution was added dropwise with 5ml 5 * 5 * 0.2cm groove Teflon mold, covered with a glass plate after dropwise over a 6 * 6 * 0.2cm on the mold, the whole is placed ultraviolet under light, a polymerization 40min. After the opened glass, good solid polymeric gel is washed off 10 ~ 20min with ethanol fro...

Example Embodiment

[0047] Example 3

[0048] In the present embodiment, on the basis of the embodiment 2 discloses a method for preparing a silicone hydrogel contact lens, comprising the steps of:

[0049] Amount of 41.7% in mass percentage in Example 1 polydimethylsiloxane macromer crosslinking agent, 22.6% by mass percentage of N'N- dimethylacrylamide (DMA), 15.9% of the mass percentage A yl acryloxy propyl tris (trimethylsiloxy) silane (Tris), 1.0% by mass percentage of Darocur 1173, was dissolved in n-propanol of 18.8% by mass percentage of diluent is magnetically stirred for 20 min, ultrasonic extinction soak for 10 minutes to the polymerization solution for use. 20μL suction pipette with the polymerization solution was added dropwise a polypropylene contact lens molds in a female mold, the male mold cover dropwise over in the mold, the whole is placed under UV light, polymerization 30min. After the reaction, the mold is opened, the lens is bonded to the surface of the mold, the mold was remove...

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Abstract

The invention relates to the technical field of corneal contact lenses, and particularly discloses a high-oxygen-permeability corneal contact lens which is made of a high-oxygen-permeability silicone hydrogel material. The high-oxygen-permeability corneal contact lens is prepared from the following components in percentage by mass through a photopolymerization reaction: 27.5 percent to 41.8 percent of a polydimethylsiloxane macromonomer cross-linking agent, 16.8 percent to 20.5 percent of a hydrophilic monomer, 15.9 percent to 22.6 percent of a micromolecular siloxane monomer, 1.0 percent to 2.5 percent of a photoinitiator and 17.5 percent to 25.0 percent of a diluent; the polydimethylsiloxane macromonomer cross-linking agent adopts a hydrophilic segment modified and double bond terminated polydimethylsiloxane macromonomer cross-linking agent. The defects in the prior art are overcome, the oxygen permeation value of the prepared corneal contact lens is 140-150, and the requirement for the most suitable oxygen permeation amount of a human body is met.

Description

technical field [0001] The invention relates to the technical field of contact lenses, in particular to a method for preparing a polysiloxane macromonomer crosslinking agent material, a method for preparing contact lenses with high oxygen transmission rate based on the material, and such contact lenses Surface hydrophilic modification technology. Background technique [0002] Contact lenses (also known as contact lenses) are lenses that are directly worn on the eyeball and are mainly used for vision correction. For some special types of work, people need to wear contact lenses to ensure eye safety. At the same time, due to people's pursuit of beauty, more young people choose to wear colored contact lenses (color contact lenses) to increase their beauty. At present, with the development of science and technology and people's additional requirements for the wearing comfort of contact lenses; therefore, the lens materials of contact lenses have also been continuously updated....

Claims

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Application Information

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IPC IPC(8): C08F290/06C08F222/38C08F230/08C08F2/48C08J7/056C08G77/388G02C7/04C08L51/08C09D133/02C09D187/00
CPCC08F290/068C08F2/48C08J7/056C08J7/042C08G77/388G02C7/049C08J2351/08C08J2433/02C08J2487/00C08F222/385C08F230/085
Inventor 王长江
Owner 吉林爱惠瞳医用科技有限公司
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