Simultaneous detection and application of volatile pollutant exposure and effect markers in urine

A technology for simultaneous detection of volatile pollutants, applied in measurement devices, instruments, scientific instruments, etc., can solve the problems of different detection instruments and analysis methods, and achieve the effects of high cost, solvent saving, and large data errors
CN113777209BActive Publication Date: 2022-02-08SOUTH CHINA INST OF ENVIRONMENTAL SCI MEP
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Patents(China)
Current Assignee / Owner
SOUTH CHINA INST OF ENVIRONMENTAL SCI MEP
Publication Date
2022-02-08

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Abstract

The invention discloses a method and application for synchronous detection of volatile pollutant exposure and effect markers in urine. The method selects OH-PAHs, mVOCs and 8-OHdG that may be correlated in the same urine sample as targets Detected substances are extracted, detected and analyzed synchronously, which includes the following steps: sample pretreatment; sample enrichment and separation; OHdG is detected on the machine, and the corresponding analysis is used to obtain the content data of various target detection substances in urine, and the correlation between the three is analyzed. The invention applies the analysis of the relationship between the content data of the target substance to evaluate the human body exposure characteristics of two types of pollutants. The invention enables synchronous detection and analysis of various target detection substances through an optimization scheme, simplifies the detection steps, reduces the detection cost, and expands the application range of the health exposure risk assessment results.
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Description

technical field

[0001] The invention belongs to the fields of pollutant detection, health exposure risk assessment and medical technology, and specifically relates to the simultaneous detection and application of volatile pollutant exposure and effect markers in urine. Background technique

[0002] Polycyclic aromatic hydrocarbons (PAHs) are a class of semi-volatile organic pollutants (SVOCs) produced by incomplete combustion of organic matter such as coal, petroleum, and tobacco. Studies have shown that exposure to PAHs may cause irritation to the digestive tract and respiratory tract, and long-term exposure can also cause damage to the human circulatory system and nervous system, resulting in teratogenic, carcinogenic, and mutagenic hazards. Volatile organic compounds (VOCs) are ubiquitous pollutants in the atmosphere, and their sources are very extensive. Industrial production, motor vehicle exhaust, cigarette smoke, and high-temperature cooking foods all produce VOCs. L...

Claims

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