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Molecular diagnostic devices with digital detection capability and wireless connectivity

A technology for molecular diagnostics, testing equipment, applied in the direction of medical automation diagnostics, heating or cooling equipment, biochemical equipment and methods, etc., can solve problems such as lack of database connectivity

Pending Publication Date: 2021-12-10
VISBY MEDICAL INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Also, known tests lack connectivity to centralized databases used to track the spread of the disease

Method used

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  • Molecular diagnostic devices with digital detection capability and wireless connectivity
  • Molecular diagnostic devices with digital detection capability and wireless connectivity
  • Molecular diagnostic devices with digital detection capability and wireless connectivity

Examples

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Embodiment Construction

[0065] In some embodiments, the device is configured for disposable, portable, single use, inexpensive molecular diagnostic methods. The device may include one or more modules configured to perform high quality molecular diagnostic tests including, but not limited to, sample preparation, nucleic acid amplification (eg, via polymerase chain reaction, isothermal amplification, etc.), and detection. In some embodiments, sample preparation can be performed by isolating pathogens / entities and removing unwanted amplification (eg, PCR) inhibitors. The target entity can then be cleaved to release the target nucleic acid for amplification. A target nucleic acid (eg, a target polynucleotide sequence) in a target entity can be temperature cycled with a polymerase or amplified via isothermal incubation to generate a larger number of copies of the target nucleic acid sequence for detection.

[0066] In some embodiments, the devices described herein are self-contained devices that include ...

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Abstract

In some embodiments, a stand-alone molecular diagnostic test device includes a detection circuit that includes a light emitting device and a light receiving device (e.g., a photodiode) that are arranged to produce an electronic signal associated with a colorimetric output produced by the stand-alone molecular diagnostic test.

Description

[0001] Cross References to Related Applications [0002] This application claims U.S. Provisional Application Serial No. 62 / 839,724, filed April 28, 2019, entitled "Molecular Diagnostic Devices with Digital Detection Capability and Wireless Connectivity," and filed January 3, 2020, entitled "Devices and U.S. Provisional Application Serial No. 62 / 957,068 for Methods for Antibiotic Susceptibility Testing," each of which is incorporated herein by reference in its entirety. technical field [0003] Embodiments described herein relate to devices and methods for molecular diagnostic testing. More particularly, embodiments described herein relate to disposable, self-contained devices and methods for molecular diagnostic testing that include digital detection capabilities and wireless connectivity that can be enabled with electronic health records and / or are designed to improve medical Operational connections to other databases of results. Background technique [0004] There are m...

Claims

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Application Information

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IPC IPC(8): B01L3/00C12N15/10B01L7/00C12Q1/37
CPCC12Q1/6834C12Q1/6825G16B20/00G16B40/10G16B25/20B01L3/502715B01L2300/0663B01L7/52B01L2200/16G01N21/76G01N2021/6439G01N21/78C12Q2563/103C12Q2563/125C12Q2565/629C12Q2565/501G16C20/10G16H10/60G16B30/10G16H10/40G16H50/20G16H80/00B01L2200/0663B01L2300/025B01L2300/023B01L2300/04B01L2300/0809
Inventor V·布里奥尼斯T·亚伯拉罕B·西奥派克P·丹廷格K·卡约克B·D·克尼什B·马
Owner VISBY MEDICAL INC
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