Cold compress gel as well as use method and application thereof
A gel and cold compress technology used in the field of medical supplies to reduce pigmentation, relieve pain, and relieve itchy skin
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Embodiment 1-3
[0025] Weigh hydroxypropylmethylcellulose, carbomer, sodium hyaluronate, glycerin, ceramide, WS-23, eucalyptus oil, glycyrrhetinic acid, sodium gualenate, turpentine according to the mass content of each component in Table 1 , poloxamer, collagen, polyethylene glycol, octenidine hydrochloride, polyhexamethylene biguanide hydrochloride and water, stir and mix evenly to obtain cold compress gel (the total mass is 10g).
[0026] Table 1
[0027]
[0028]
Embodiment 4
[0030] Adopt public opinion survey scoring method, select 45 volunteers (including 15 breastfeeding pregnant women, 15 children aged 10-13, 15 adults aged 25-50), arbitrarily divided into three groups, respectively prepared with embodiment 1-3 Apply the cold compress gel to the affected area (caused by mosquito bites) 3 times a day for a week. The total score of each effect is 10 points: 10 is the highest score, which means very good; 7 is good; 5 is acceptable; below 5 is not good. The results are shown in Table 2:
[0031] Table 2
[0032]
Embodiment 5
[0033] Embodiment 5 bactericidal performance test
[0034] 1. Experimental equipment
[0035] 1.1 Experimental strains: Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans.
[0036] 1.2 Experimental reagents: tryptone soy agar medium, Sabouraud dextrose agar medium, 0.9% sterile saline.
[0037] 1.3 Equipment and consumables: micropipette, disposable tip, test tube, vertical high-pressure steam sterilizer, biological clean safety cabinet, electric mixer, intelligent biochemical incubator, mold incubator.
[0038] 2. Experimental steps:
[0039] 2.1 Preparation of disinfectant, i.e. the cold compress gel in Example 1
[0040] 2.2 Bacterial suspension preparation:
[0041] table 3
[0042]
[0043] According to the requirements of the inoculum in Table 3, Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans were centrifuged to collect the thalli, and were diluted step by step with 0.9% sterile saline to make the number of bacteria per lm l a...
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