Biological membrane collagen beam orientation optical detection method and system based on weak coherent interference
An optical detection and biofilm technology, which is applied in the measurement of phase influence characteristics, color/spectral characteristics, etc., can solve the problems of inability to obtain the orientation distribution of collagen bundles and take a long time
Pending Publication Date: 2022-04-12
JIAXING RES INST ZHEJIANG UNIV +1
View PDF13 Cites 0 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Although this method is also non-destructive testing, it needs to continuously rotate the direction of the polarizer to obtain the average orientation of the collagen bundles, which takes a long time and cannot obtain the orientation distribution of collagen bundles at different depths in the biofilm.
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreImage
Smart Image Click on the blue labels to locate them in the text.
Smart ImageViewing Examples
Examples
Experimental program
Comparison scheme
Effect test
Embodiment Construction
[0042] Specific embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings, which form a part of this document. It should be noted that these descriptions and examples are illustrative only, and should not be construed as limiting the scope of the present invention. The protection scope of the present invention is defined by the appended claims, and any changes based on the claims of the present invention All are protection scope of the present invention.
[0043] In order to facilitate the understanding of the embodiments of the present invention, each operation is described as a plurality of discrete operations, however, the order of description does not represent the order in which the operations are performed.
[0044] In this description, the x-y-z three-dimensional coordinate representation based on the spatial direction is used for the sample measurement space. This description is provided merely to facilitate d...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More PUM
Login to View More Abstract
The invention discloses a weak coherence interference-based biological membrane collagen beam orientation optical detection method and a weak coherence interference-based biological membrane collagen beam orientation optical detection system. The method comprises the following steps: acquiring a biofilm interference spectrum by using an optical coherence imaging system, performing Fourier transform on the interference spectrum to obtain a depth domain intensity signal, calculating a biofilm surface coordinate based on the depth domain intensity signal, fitting a biofilm surface curve by using a polynomial, and performing coordinate transform on the biofilm according to the fitted curve to enable the surface of the biofilm to tend to be horizontal. And performing intensity signal projection of different depths on the leveled biological membrane, wherein an intensity signal projection drawing can display the collagen beam orientation characteristics of the biological membrane. According to the method, the depth-distinguishable (micrometer precision) biological membrane collagen beam orientation can be obtained through one-time imaging, and the edge of the cutting biological membrane can be rapidly evaluated to obtain high-quality artificial heart biological valve leaflets.
Description
technical field [0001] The invention relates to the detection of the orientation of collagen bundles of bioprosthetic tissues used for implants, and more particularly to an optical non-destructive detection method for the orientation of collagen bundles of biological membranes made of leaflets of artificial heart biological valves. Background technique [0002] A normal natural heart consists of the aortic, mitral, tricuspid and pulmonary valves, each of which has one-way leaflets that control the directional flow of blood through the heart. When the heart valve is diseased or damaged, in order for the heart to work normally, valve replacement surgery can be performed to replace the human body's own heart valve with an artificial heart biovalve. [0003] Artificial heart biological valves are made of biological tissue materials, such as using bovine pericardium tissue and pig pericardium tissue to make a single leaflet of artificial heart biological valves. A typical proced...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More Application Information
Patent Timeline
Login to View More Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/45G01N21/25
Inventor 李鹏姚霖
Owner JIAXING RES INST ZHEJIANG UNIV