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Aqueous spray and preparation method thereof

A technology of water agent and moisturizer, which is applied in the direction of pharmaceutical formulations, cosmetic preparations, cosmetic preparations, etc., to achieve good air permeability and non-irritating effects on the skin

Pending Publication Date: 2022-06-17
彭氏(惠州)实业发展有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the current spray water agents on th

Method used

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  • Aqueous spray and preparation method thereof
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  • Aqueous spray and preparation method thereof

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[0044]应当理解，此处所描述的具体实施例仅仅用以解释本发明，并不用于限定本发明。

[0045]实施例1-4提供的喷雾水剂中所采用的组份配比如表1所示。

[0046]实施例1-4提供的喷雾水剂为无色或淡黄色透明低粘液体。

[0047]表1

[0048]

[0049]实施例1-4提供的喷雾水剂的制备方法均包括以下步骤：

[0050]步骤一，将去离子水加入水相锅内，同时在搅拌状态下进行升温至80℃并保持恒温状态，在搅拌状态下将祛皱功效剂、保湿剂、增稠剂加入水相锅内搅拌均匀；

[0051]步骤二，将稳定剂加入水相锅内，搅拌至溶解完全；

[0052]步骤三，将水相锅内的液体用400目过滤布过滤后抽至乳化锅内，升温至80℃℃后保持恒温状态30min，然后进行冷却降温；

[0053]步骤四，乳化锅内液体的温度不高于45℃后加入皮肤调理剂和防腐剂，将增溶剂和香精混合搅拌均匀后加入至乳化锅内，搅拌均匀后加入pH调节剂调节乳化锅内液体的pH值至6.0-7.0。

[0054]步骤五，乳化锅内液体的温度降温至室温后进行出料和检测，各项指标合格后灌装入瓶得到喷雾水剂。

[0055]随机选取受试者对实施例1提供的喷雾水剂的使用功效进行评估。

[0056]一、受试者要求：

[0057]1.年龄35-55岁健康女性；

[0058]2.肤色暗沉，无光泽，皮肤松弛下垂，失去弹性

[0059]3.皮肤粗糙干燥，皱纹明显

[0060]4.能很好配合试验者，在研究期间能保持生活的规律性；

[0061]5.能够阅读和理解知情，同意书所有内容，并自愿签署知情同意书；

[0062]6.试验期间不再参与其他任何研究中心的临床试验；

[0063]7.试验期间同意不使用任何对结果有影响的化妆品、药物和保健品。

[0064]二、受试者的排除标准：

[0065]1.测试部位有皮肤疾病或者瑕疵而可能影响试验结果判断者

[0066]2.高度过敏体质者；

[0067]3.妊娠、哺乳或在测试期间打算怀孕的女性；

[0068]4.有严重心、肝、肾功能损害及严重免疫功能低下者，或近一个月内使用免疫抑制剂者；

[0069]5.有精神疾病、严重内分泌疾病以及口服避孕药者；

[0070]6.30d内参加药物临床试验者或其它试验者，或近1周内系统使用对试验结果有影响的药物者；

[0071]7.2周内有口服和外用可能对试验结果有影响的美容产品者；

[0072]8.不能配合试验者。

[0073...

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Abstract

The invention relates to a spray aqueous solution which comprises deionized water and the following components in percentage by weight: 0.5-5% of a wrinkle-removing functional agent, 0.5-5% of a preservative, 0.5-5% of a preservative and the balance of water. 0.5 to 5% of a humectant; 0.01 to 5% of a skin conditioning agent; 0.001 to 0.1% of a thickening agent; 0.1%-0.3% of a preservative; 0.1 to 0.5% of a solubilizer; 0.01%-0.5% of a pH conditioning agent; 0.1 to 0.5 percent of a stabilizing agent; and 0.001 to 0.1 percent of essence. The invention also relates to a method for preparing the spray aqueous solution.

Description

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Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/04A61K8/34A61K8/60A61K8/64A61K8/81A61Q19/00A61Q19/08
CPCA61K8/8188A61K8/602A61K8/64A61K8/9789A61K8/345A61K8/60A61K8/046A61Q19/08A61Q19/00
Inventor 许晓煌
Owner 彭氏(惠州)实业发展有限公司